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公开(公告)号:US20170252490A1
公开(公告)日:2017-09-07
申请号:US15503758
申请日:2015-09-23
Applicant: Sofradim Production
Inventor: Nicolas Prost , Delphine Petit , Xavier Bourges
Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7%, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.
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公开(公告)号:US20250018092A1
公开(公告)日:2025-01-16
申请号:US18813240
申请日:2024-08-23
Applicant: SOFRADIM PRODUCTION
Inventor: Nicolas Prost , Delphine Petit , Xavier Bourges
IPC: A61L31/04 , A61F2/00 , A61L27/34 , A61L27/58 , A61L31/10 , A61L31/14 , B29C41/02 , B29C41/12 , B29C41/22 , B29C41/24 , C08J5/18 , C08J7/04 , C08L89/06
Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7%, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.
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公开(公告)号:US20210189616A1
公开(公告)日:2021-06-24
申请号:US17117083
申请日:2020-12-09
Applicant: SOFRADIM PRODUCTION
Inventor: Suzelei Montanari , Yves Bayon , Xavier Bourges , Delphine Petit
Abstract: The present invention relates to a prosthetic fabric (5) comprising an arrangement (2) of yarns that define at least first and second opposite faces (2a, 2b) for said fabric, said fabric comprising on at least said first face, one or more barbs (3) that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.
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公开(公告)号:US10549015B2
公开(公告)日:2020-02-04
申请号:US15503758
申请日:2015-09-23
Applicant: Sofradim Production
Inventor: Nicolas Prost , Delphine Petit , Xavier Bourges
IPC: A61L31/04 , A61L31/10 , A61F2/00 , A61L27/34 , A61L27/58 , A61L31/14 , C08J5/18 , C08J7/04 , B29C41/12 , B29C41/22 , B29C41/24 , B29C41/02
Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7 %, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.
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公开(公告)号:US12070534B2
公开(公告)日:2024-08-27
申请号:US16717112
申请日:2019-12-17
Applicant: Sofradim Production
Inventor: Nicolas Prost , Delphine Petit , Xavier Bourges
IPC: A61L31/04 , A61F2/00 , A61L27/34 , A61L27/58 , A61L31/10 , A61L31/14 , B29C41/02 , B29C41/12 , B29C41/22 , B29C41/24 , C08J5/18 , C08J7/04 , C08L89/06
CPC classification number: A61L31/044 , A61F2/0063 , A61F2/0077 , A61L27/34 , A61L27/58 , A61L31/10 , A61L31/148 , C08J5/18 , C08J7/0427 , C08L89/06 , A61F2002/009 , A61L2400/18 , A61L2420/08 , B29C41/02 , B29C41/12 , B29C41/22 , B29C41/24 , C08J2389/06 , C08J2489/06 , A61L31/10 , C08L89/06
Abstract: The present invention relates to a surgical anti-adhesion barrier film comprising an oxidized collagen and a polyphosphate compound and to a surgical implant comprising a prosthetic fabric and such a film.
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公开(公告)号:US20240279852A1
公开(公告)日:2024-08-22
申请号:US18651284
申请日:2024-04-30
Applicant: SOFRADIM PRODUCTION
Inventor: Suzelei Montanari , Yves Bayon , Xavier Bourges , Delphine Petit
CPC classification number: D04B21/12 , A61F2/0063 , A61L27/34 , A61L27/50 , A61L27/54 , A61L27/56 , A61F2/0077 , A61F2002/30322 , A61F2220/0016 , A61F2250/0026 , A61F2250/0031 , A61L2300/61 , D10B2403/0112 , D10B2501/0632 , D10B2509/08
Abstract: The present invention relates to a prosthetic fabric (5) comprising an arrangement (2) of yarns that define at least first and second opposite faces (2a, 2b) for said fabric, said fabric comprising on at least said first face, one or more barbs (3) that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.
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公开(公告)号:US11970798B2
公开(公告)日:2024-04-30
申请号:US17117083
申请日:2020-12-09
Applicant: SOFRADIM PRODUCTION
Inventor: Suzelei Montanari , Yves Bayon , Xavier Bourges , Delphine Petit
CPC classification number: D04B21/12 , A61F2/0063 , A61L27/34 , A61L27/50 , A61L27/54 , A61L27/56 , A61F2/0077 , A61F2002/30322 , A61F2220/0016 , A61F2250/0026 , A61F2250/0031 , A61L2300/61 , D10B2403/0112 , D10B2501/0632 , D10B2509/08 , A61L27/34 , C08L29/04
Abstract: The present invention relates to a prosthetic fabric (5) comprising an arrangement (2) of yarns that define at least first and second opposite faces (2a, 2b) for said fabric, said fabric comprising on at least said first face, one or more barbs (3) that protrude outwards relative to said first face, said fabric being covered, at least partly, on said second face with a microporous layer made of a bioresorbable material, said barbs being covered with a coating made of a water-soluble material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.
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