公开(公告)号：US3666628A

公开(公告)日：1972-05-30

申请号：US3666628D

申请日：1971-03-19

Applicant: STANDARD BRANDS INC

Inventor： DWORSCHACK ROBERT G ,  LAMM WILLIAM R

IPC: C12N1/20 ,  C12N1/38 ,  C12N9/92 ,  C12D13/10 ,  C12B1/20

CPC classification number: C12N9/92 ,  C12N1/20 ,  C12N1/38 ,  Y10S435/886

Abstract: UNDER SUBMERGED, AEROBIC CULTURE CONDITIONS, THE MYCELIA OF MANY MICROORGANISMS OF THE STREPTOMYCES GENUS HAVE A TENDENCY TO GROW IN THE FORM OF COMPACT SPHERICAL MASSES. WHEN SMALL AMOUNTS OF AQUEOUS DISPERSIBLE MATERIALS ARE PRESENT IN THE GROWTH MEDIUM, THE MYCELIA PRODUCED WILL BE OF THE FILAMENTOUS FORM. THE PRESENCE OF SUCH MYCELIA WILL RESULT IN RAPID GROWTH OF THE MICROORGANISMS AND IMPROVED ENZYME PRODUCTION. EXAMPLES OF DISPERSIBLE MATERIALS ARE AGAR, CARBOXYMETHYLCELLULOSE, AND DIATOMACEOUS EARTH.

公开(公告)号：US3654080A

公开(公告)日：1972-04-04

申请号：US3654080D

申请日：1970-01-05

Applicant: STANDARD BRANDS INC

Inventor： BENGTSON BARBARA L ,  LAMM WILLIAM R

IPC: C12N9/92 ,  C12B1/00 ,  C12C11/04 ,  C12D

CPC classification number: C12N9/92 ,  Y10S435/886

Abstract: THE DISCLOSURE IS DIRECTED TO A PROCESS OF ENZYMATICALLY CONVERTING A PORTION OF THE GLUCOSE IN A GLUCOSE-CONTAINING SOLUTION TO FRUCTOSE. VIABLE MICROORGANISM WHICH CONTAIN INTRACELLULAR GLUCOSE ISOMERASE ARE TREATED WITH A TOXIC AGENT OT DESTROY AT LEAST 95 PERCENT OF THE MICROORGANISMS. THE TREATED MICROORGANISM ARE CULTURED TO PROMOTE GROWTH, AND THE CELLULAR MATERIAL THEREFROM IS INCORPORATED INTO A GLUCOSE SOLUTION WHEREIN CONDITIONS ARE MAINTAINED TO CONVERT A PORTION OF THE GLUCOSE TO FRUCTOSE.