公开(公告)号：US09453253B2

公开(公告)日：2016-09-27

申请号：US14404134

申请日：2013-03-07

Applicant: STC.UNM ,  THE JOHNS HOPKINS UNIVERSITY

Inventor： Graham Timmins ,  Seong Choi ,  Zachary Sharp ,  Viorel Atudorei ,  Mamoudou Maiga ,  William Bishai

IPC: G01N33/60 ,  C12Q1/04 ,  G01N33/569 ,  C12Q1/28

CPC classification number: C12Q1/04 ,  C12Q1/28 ,  C12Q2304/48 ,  G01N33/5695 ,  G01N33/60 ,  G01N2333/35

Abstract: The present invention is directed to methods of diagnosing the presence or absence of a bacterial infection in a patient, in particular, a tuberculosis infection, by measuring exhaled, isotopically labeled nitrogen gas after administration of isotopically labeled isoniazid.

Abstract translation: 本发明涉及通过在施用同位素标记的异烟肼之后测量呼出的，同位素标记的氮气来诊断患者中细菌感染的存在或不存在，特别是结核病感染的方法。

公开(公告)号：US20150104819A1

公开(公告)日：2015-04-16

申请号：US14404134

申请日：2013-03-07

Applicant: STC.UNM ,  THE JOHNS HOPKINS UNIVERSITY

Inventor： Graham Timmins ,  Seong Choi ,  Zachary Sharp ,  Viorel Atudorei ,  Mamoudou Maiga ,  William Bishai

IPC: C12Q1/04 ,  C12Q1/28

CPC classification number: C12Q1/04 ,  C12Q1/28 ,  C12Q2304/48 ,  G01N33/5695 ,  G01N33/60 ,  G01N2333/35

Abstract: The present invention is directed to methods of diagnosing the presence or absence of a bacterial infection in a patient, in particular, a tuberculosis infection, by measuring exhaled, isotopically labeled nitrogen gas after administration of isotopic ally labeled isoniazid.

Abstract translation: 本发明涉及通过在施用同位素标记的异烟肼之后测量呼出的同位素标记的氮气来诊断患者中细菌感染的存在或不存在，特别是结核病感染的方法。