Abstract:
Provided is a method of generating a toxicity prediction model for a microorganism, a method of predicting the toxicity of a chemical substance to a microorganism using the toxicity prediction model, and a method of assigning priorities to biosynthetic pathways for a target material using the toxicity prediction method.
Abstract:
Use of a metabolic network model for analyzing metabolic characteristics of microorganisms for producing a metabolic product, such as 3HP enabling estimation of productivity and cell growth speed of microorganisms, optimizing new metabolic pathway, and providing transformed microorganisms that may produce a specific metabolic product with high efficiency.