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公开(公告)号:US20060183186A1
公开(公告)日:2006-08-17
申请号:US10499698
申请日:2002-12-20
申请人: Sang Koh , Qing Liu , Hyun-Ho Chung , Wen Zeng , Bogman Lee , Subrahmanyam Yeramilli , Si Song
发明人: Sang Koh , Qing Liu , Hyun-Ho Chung , Wen Zeng , Bogman Lee , Subrahmanyam Yeramilli , Si Song
IPC分类号: C12P21/06
CPC分类号: G01N33/57446 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158
摘要: The present invention results from the examination of tissue from stomach tumors to identify genes that are differentially expressed between cancerous and normal tissue. The invention includes diagnostic, monitoring, drug design and therapeutic methods using these genes, as well as solid supports comprising oligonucleotide arrays that are complementary to or hybridize to the differentially expressed genes.
摘要翻译: 本发明是由来自胃肿瘤的组织的检查来鉴定在癌组织和正常组织之间差异表达的基因。 本发明包括使用这些基因的诊断,监测,药物设计和治疗方法,以及包含与差异表达基因互补或杂交的寡核苷酸阵列的固体支持物。
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公开(公告)号:US20080050719A1
公开(公告)日:2008-02-28
申请号:US10499695
申请日:2002-12-20
申请人: Sang Seok Koh , Qing Liu , Hyun-Ho Chung , Weu Zeng , Bogman Lee , Subrahmanyam Yeramilli , Si Young Song
发明人: Sang Seok Koh , Qing Liu , Hyun-Ho Chung , Weu Zeng , Bogman Lee , Subrahmanyam Yeramilli , Si Young Song
CPC分类号: C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , Y02A90/26
摘要: The present invention results from the examination of tissue from hepatic carcinomas to identify genes differentially expressed between cancerous liver tissue and diseased but non-cancerous liver tissue. The invention includes diagnostic, screening, drug design and therapeutic methods using these genes, as well as solid supports comprising oligonucleotide arrays that are complementary to or hybridize to the differentially expressed genes.
摘要翻译: 本发明是通过检查来自肝癌的组织来鉴定癌肝组织与患病非癌肝组织之间差异表达的基因。 本发明包括使用这些基因的诊断,筛选,药物设计和治疗方法,以及包含与差异表达基因互补或杂交的寡核苷酸阵列的固体支持物。
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公开(公告)号:US07718787B2
公开(公告)日:2010-05-18
申请号:US10530837
申请日:2003-10-16
申请人: Soojin Lee , Sang Seok Koh , Bogman Lee , Hyun-Ho Chung , Seung-Ho Choo , Doo Seok Yang
发明人: Soojin Lee , Sang Seok Koh , Bogman Lee , Hyun-Ho Chung , Seung-Ho Choo , Doo Seok Yang
CPC分类号: C07K14/4748 , A61K38/00 , C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要: The invention relates generally to the changes in gene expression in human tissues from cancer patients. The invention relates specifically to human gene families which are differentially expressed in cancer tissues of breast, colon, esophagus, kidney, liver, lung, lymph node, ovary, pancreas, prostate, rectum, and/or stomach compared to corresponding normal tissues.
摘要翻译: 本发明一般涉及来自癌症患者的人体组织中基因表达的变化。 本发明具体涉及与相应的正常组织相比在乳腺,结肠,食管,肾,肝,肺,淋巴结,卵巢,胰腺,前列腺,直肠和/或胃的癌组织中差异表达的人类基因家族。
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公开(公告)号:US20060168670A1
公开(公告)日:2006-07-27
申请号:US10530837
申请日:2003-10-16
申请人: Soojin Lee , Sang-Seok Koh , Bogman Lee , Hyun-Ho Chung , Seung-Ho Choo , Doo Yang
发明人: Soojin Lee , Sang-Seok Koh , Bogman Lee , Hyun-Ho Chung , Seung-Ho Choo , Doo Yang
IPC分类号: A01K67/027 , C12Q1/68 , C07K14/82 , C07H21/04
CPC分类号: C07K14/4748 , A61K38/00 , C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要: The invention relates generally to the changes in gene expression in human tissues from cancer patients. The invention relates specifically to human gene families which are differentially expressed in cancer tissues of breast, colon, esophagus, kidney, liver, lung, lymph node, ovary, pancreas, prostate, rectum, and/or stomach compared to corresponding normal tissues.
摘要翻译: 本发明一般涉及来自癌症患者的人体组织中基因表达的变化。 本发明具体涉及与相应的正常组织相比在乳腺,结肠,食管,肾,肝,肺,淋巴结,卵巢,胰腺,前列腺,直肠和/或胃的癌组织中差异表达的人类基因家族。
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