-
公开(公告)号：US10076397B2
公开(公告)日：2018-09-18
申请号：US14377883
申请日：2013-03-22
Applicant: Sofradim Production
Inventor： Sebastien Francois , Sebastien Ladet
CPC classification number: A61F2/0063 , A61F2002/0072 , A61F2240/005 , A61F2250/0087 , A61F2250/0091 , A61F2250/0097 , G01B5/00
Abstract: The invention relates to a device (1) and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet (2) of transparent material, the said sheet comprising: —a plurality of graphical representations (3a, 3b, 4a, 4b, 5a, 5b, 5c, 5d) concentrically embodying the respective outlines of various shapes and sizes of prosthesis, —a plurality of first holes (6a, 6b, 6c, 6d, 6e, 7a, 7b, 7c, 7d, 7e) arranged along the transverse line passing through the center of the said sheet, and—a plurality of second holes (8a, 8b, 8c, 8d, 8e, 8f, 8g, 9a, 9b, 9c, 9d, 9e, 9f, 9g) arranged along the longitudinal line passing through the center (C) of the said sheet.
-
公开(公告)号：US20170290956A1
公开(公告)日：2017-10-12
申请号：US15511661
申请日：2015-09-25
Applicant: Sofradim Production
Inventor： Robert Vestberg , Sebastien Ladet , Mylene Desorme , Camille Noorman
CPC classification number: A61L31/042 , A61L27/20 , A61L27/56 , A61L27/58 , A61L31/14 , A61L31/146 , A61L31/148 , A61L2400/04 , C08B37/0003 , C08L5/08
Abstract: The present invention relates to a method for preparing a chitosan matrix having good mechanical properties comprising the steps of a) preparing a solution of chitosan, b) pouring the solution of a) into a mould in order to form a layer, c) lyophilizing the layer of b) in order to obtain a matrix of chitosan, d) sterilizing the matrix obtained in c) by water vapor treatment. The invention also relates to the matrices obtained and to surgical implants comprising such matrices. The invention further relates to a method for increasing the suture retention strength of a chitosan matrix obtained by lyophilization of a chitosan solution, and to a method for for decreasing the solubilization rate in hydrochloric acid of a chitosan matrix obtained by lyophilization of a chitosan solution, comprising the step of sterilizing said matrix by a water vapor treatment.
-
公开(公告)号：US20150080918A1
公开(公告)日：2015-03-19
申请号：US14397212
申请日：2013-06-28
Applicant: Sofradim Production
Inventor： Julie Lecuivre , Sebastien Ladet
IPC: A61F2/00
CPC classification number: A61F2/0063 , A61F2210/0076 , A61F2220/0016 , A61F2250/005 , D04B21/12 , D10B2509/08
Abstract: The present invention relates to a prosthesis (200) comprising:—at least one layer of a flexible mesh (1) delimited by a peripheral outer edge (1a), said mesh having a first colour, and—at least one layer (2) of porous material fixed to said mesh substantially along the perimeter of said peripheral outer edge, said layer of porous material being recessed at its central part (4), said layer of porous material having a second colour, different from said first colour.
Abstract translation: 本发明涉及一种假体（200），包括：至少一层柔性网（1），其由周边外缘（1a）限定，所述网具有第一颜色和至少一层（2） 多孔材料基本上沿着所述周边外边缘的周边固定到所述网状物上，所述多孔材料层在其中心部分（4）处凹入，所述多孔材料层具有不同于所述第一颜色的第二颜色。
-
公开(公告)号：US09801705B2
公开(公告)日：2017-10-31
申请号：US14397212
申请日：2013-06-28
Applicant: Sofradim Production
Inventor： Julie Lecuivre , Sebastien Ladet
CPC classification number: A61F2/0063 , A61F2210/0076 , A61F2220/0016 , A61F2250/005 , D04B21/12 , D10B2509/08
Abstract: The present invention relates to a prosthesis (200) comprising:—at least one layer of a flexible mesh (1) delimited by a peripheral outer edge (1a), said mesh having a first color, and—at least one layer (2) of porous material fixed to said mesh substantially along the perimeter of said peripheral outer edge, said layer of porous material being recessed at its central part (4), said layer of porous material having a second color, different from said first color.
-
公开(公告)号：US09527929B2
公开(公告)日：2016-12-27
申请号：US14596672
申请日：2015-01-14
Applicant: Sofradim Production
Inventor： Sebastien Francois , Sebastien Ladet , Muriel Guerin
CPC classification number: C08B37/003 , C07H1/08
Abstract: The present invention relates to a method for the preparation of chitosan of a degree of acetylation DAr, from chitosan β having a degree of acetylation DAi lower than DAr, comprising at least one step of purification and at least one step of acetylation of said chitosan β, said purification step comprising at least one step of solubilization of said chitosan β in an acidic aqueous medium and at least one step of precipitation of said thus solubilized chitosan, wherein said acetylation step is carried out in a solution on said solubilized chitosan before said precipitation step.
Abstract translation: 具有高乙酰化度的壳聚糖的制备方法本发明涉及由具有乙酰化度DA的壳聚糖f3制备乙酰化度DA r的壳聚糖的方法; 包括至少一个纯化步骤和所述壳聚糖2的至少一个乙酰化步骤，所述纯化步骤包括将所述壳聚糖f 3溶解在酸性水性介质中的至少一个步骤和至少一个沉淀步骤 的所述溶解的壳聚糖，其中所述乙酰化步骤在所述沉淀步骤之前在所述溶解的壳聚糖上的溶液中进行，所述沉淀步骤包括病毒失活步骤。
-
Patent Agency Ranking
公开(公告)号：US20150210780A1
公开(公告)日：2015-07-30
申请号：US14596672
申请日：2015-01-14
Applicant: Sofradim Production
Inventor： Sebastien Francois , Sebastien Ladet , Muriel Guerin
IPC: C08B37/08
CPC classification number: C08B37/003 , C07H1/08
Abstract: The present invention relates to a method for the preparation of chitosan of a degree of acetylation DAr, from chitosan β having a degree of acetylation DAi lower than DAr, comprising at least one step of purification and at least one step of acetylation of said chitosan β, said purification step comprising at least one step of solubilization of said chitosan β in an acidic aqueous medium and at least one step of precipitation of said thus solubilized chitosan, wherein said acetylation step is carried out in a solution on said solubilized chitosan before said precipitation step.
Abstract translation: 本发明涉及一种从壳聚糖和bgr制备乙酰化度DAr的壳聚糖的方法。 具有低于DAr的乙酰化度DAi，其包含至少一个纯化步骤和所述壳聚糖和bgr的至少一个乙酰化步骤;所述纯化步骤包括至少一个步骤：使所述壳聚糖和bgr的溶解; 在酸性水性介质中和所述溶解的壳聚糖沉淀的至少一个步骤，其中所述乙酰化步骤在所述沉淀步骤之前在所述溶解的壳聚糖的溶液中进行。
-
公开(公告)号：US20140128497A1
公开(公告)日：2014-05-08
申请号：US14154338
申请日：2014-01-14
Applicant: SOFRADIM PRODUCTION
Inventor： Sebastien Ladet , Philippe Gravagna
IPC: A61L24/00
CPC classification number: A61L24/0031 , A61K9/06 , A61L24/046 , C08L101/02
Abstract: A bioadherent substrate includes a medical gel or medical gel precursor having a plurality of reactive members of a specific binding pair attached on or adapted to be attached to a surface of the medical gel, said reactive members being capable of forming covalent bonds with a plurality of complementary reactive members of the specific binding pair via a reaction selected from a Huisgen cycloaddition reaction, a Diels-Alder reaction and a thiol-ene reaction. A method for adhering a medical gel to biological tissue includes providing a medical gel or a medical gel precursor having a plurality of reactive members of a specific binding pair attached on or adapted to be attached to a surface of the medical gel and providing tissue with a plurality of complementary reactive members of the specific binding pair, wherein upon contact of the reactive members on the medical gel with the complimentary reactive members on the tissue, covalent bonds are formed between the reactive members and the complementary reactive members, thus adhering the medical gel to the tissue.
Abstract translation: 生物粘附底物包括医学凝胶或医用凝胶前体，其具有连接在或适于附着在医用凝胶表面上的特定结合对的多个反应性成员，所述反应性成员能够与多个 通过选自Huisgen环加成反应，Diels-Alder反应和硫醇 - 烯反应的反应的特异性结合对的互补反应性成员。 将医用凝胶粘附到生物组织上的方法包括提供具有多个特异性结合对的反应性成员的医用凝胶或医用凝胶前体，所述多个反应性成员附着于或适于附着在医用凝胶的表面上， 多个特异性结合对的互补反应性成员，其中当在医用凝胶上的反应性成员与组织上的互补反应性成员接触时，在反应性部件和互补的反应性部件之间形成共价键，从而粘附医用凝胶 到组织。
-
公开(公告)号：US10945823B2
公开(公告)日：2021-03-16
申请号：US16128547
申请日：2018-09-12
Applicant: Sofradim Production
Inventor： Sebastien Francois , Sebastien Ladet
Abstract: The invention relates to a device (1) and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet (2) of transparent material, the said sheet comprising: —a plurality of graphical representations (3a, 3b, 4a, 4b, 5a, 5b, 5c, 5d) concentrically embodying the respective outlines of various shapes and sizes of prosthesis, —a plurality of first holes (6a, 6b, 6c, 6d, 6e, 7a, 7b, 7c, 7d, 7e) arranged along the transverse line passing through the centre of the said sheet, and —a plurality of second holes (8a, 8b, 8c, 8d, 8e, 8f, 8g, 9a, 9b, 9c, 9d, 9e, 9f, 9g) arranged along the longitudinal line passing through the centre (C) of the said sheet.
-
公开(公告)号：US20190008624A1
公开(公告)日：2019-01-10
申请号：US16128547
申请日：2018-09-12
Applicant: Sofradim Production
Inventor： Sebastien Francois , Sebastien Ladet
Abstract: The invention relates to a device (1) and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet (2) of transparent material, the said sheet comprising: —a plurality of graphical representations (3a, 3b, 4a, 4b, 5a, 5b, 5c, 5d) concentrically embodying the respective outlines of various shapes and sizes of prosthesis, —a plurality of first holes (6a, 6b, 6c, 6d, 6e, 7a, 7b, 7c, 7d, 7e) arranged along the transverse line passing through the centre of the said sheet, and —a plurality of second holes (8a, 8b, 8c, 8d, 8e, 8f, 8g, 9a, 9b, 9c, 9d, 9e, 9f, 9g) arranged along the longitudinal line passing through the centre (C) of the said sheet.
-
公开(公告)号：US20150050417A1
公开(公告)日：2015-02-19
申请号：US14528071
申请日：2014-10-30
Applicant: Sofradim Production
Inventor： Sebastien Ladet , Philippe Gravagna
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L17/005 , A61L17/145 , A61L31/16 , A61L2300/252 , A61L2300/256 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/43 , A61L2300/606 , A61L2400/18 , A61L2420/02
Abstract: Implantable non-bioabsorbable medical devices have an amphiphilic coating for reducing the inflammatory response to the device after implantation.
Abstract translation: 植入式非生物可吸收医疗器械具有两性涂层，用于在植入后减少对器件的炎症反应。
-
-
-
-
-
-
-
-
-
Search Results
14
records
(took 0.03 seconds)
