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    Contrast agent imaging with destruction pulses in diagnostic medical ultrasound
    1.
    发明授权
    Contrast agent imaging with destruction pulses in diagnostic medical ultrasound 有权
    在诊断医学超声中具有破坏脉冲的造影剂成像

    公开(公告)号：US06340348B1

    公开(公告)日：2002-01-22

    申请号：US09348246

    申请日：1999-07-02

    申请人： Sriram Krishnan ,  Gregory L. Holley ,  Edward A. Gardner ,  Samuel H. Maslak

    发明人： Sriram Krishnan ,  Gregory L. Holley ,  Edward A. Gardner ,  Samuel H. Maslak

    IPC分类号： A61B800

    CPC分类号： A61B8/481 ,  A61B8/543 ,  A61B17/22004 ,  A61B2017/22008

    摘要： The invention is directed to improvements in diagnostic medical ultrasound contrast agent imaging. In a preferred embodiment, high pulse repetition frequency (HPRF) destruction pulses are fired at a rate higher than necessary for receiving returning echoes. Pulse parameters can also be changed between the plurality of contrast agent-destroying pulses. Other preferred embodiments of the invention are directed to simultaneous transmission of multiple beams of destruction pulses. Destruction frames that consist of a plurality of destruction pulses can be triggered and swept over the entire region of tissue being imaged and at a variety of focal depths from the transmitter. The destruction frames are fired at some time triggered from a timer or some fixed part of a physiological signal, such as an ECG signal. Other preferred embodiments of the invention are directed to continuous low power imaging pulses alternating with destruction pulses triggered at a fixed point of a physiological signal, and a comparison of the received signals from imaging pulses fired before and after the destruction pulses. Alternatively, destruction pulses are triggered at a fixed point on a physiological signal different from the fixed point of a physiological signal used to trigger imaging pulses. In another embodiment, triggered destruction frames are used to enable a comparison of imaging frames in order to determine physiological functions, such as perfusion of blood in cardiac tissue. Finally, in another embodiment, destruction pulses are combined with subharmonic imaging.

    摘要翻译： 本发明涉及诊断医学超声造影剂成像的改进。 在优选实施例中，高脉冲重复频率（HPRF）破坏脉冲以高于接收返回回波所需的速率被发射。 也可以在多个造影剂破坏脉冲之间改变脉冲参数。 本发明的其它优选实施例涉及同时传输多束破坏脉冲。 由多个破坏脉冲组成的破坏帧可以被触发并扫过被成像的组织的整个区域并且在来自发射器的各种焦深处扫过。 在由定时器或生理信号的某些固定部分（例如ECG信号）触发的某个时间触发破坏帧。 本发明的其它优选实施例涉及与生理信号的固定点触发的破坏脉冲交替的连续低功率成像脉冲，以及在破坏脉冲之前和之后激发的成像脉冲的接收信号的比较。 或者，在与用于触发成像脉冲的生理信号的固定点不同的生理信号上的固定点触发销毁脉冲。 在另一个实施例中，触发的破坏帧用于使成像帧的比较能够确定生理功能，例如心脏组织中血液的灌注。 最后，在另一个实施例中，销毁脉冲与次谐波成像组合。

    Multiple ultrasound image registration system, method and transducer
    2.
    发明授权
    Multiple ultrasound image registration system, method and transducer 失效
    多重超声图像配准系统，方法和传感器

    公开(公告)号：US06360027B1

    公开(公告)日：2002-03-19

    申请号：US09669818

    申请日：2000-09-26

    申请人： John A. Hossack ,  John W. Sliwa, Jr. ,  Samuel H. Maslak ,  Edward A. Gardner ,  Gregory L. Holley ,  David J. Napolitano

    发明人： John A. Hossack ,  John W. Sliwa, Jr. ,  Samuel H. Maslak ,  Edward A. Gardner ,  Gregory L. Holley ,  David J. Napolitano

    IPC分类号： G06K900

    CPC分类号： A61B8/145 ,  A61B8/483 ,  G01S7/52034 ,  G01S7/52065 ,  G01S7/52071 ,  G01S7/52085 ,  G01S15/66 ,  G01S15/87 ,  G01S15/8934 ,  G01S15/8979 ,  G01S15/8993 ,  G06T7/246

    摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

    摘要翻译： 超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。 跟踪阵列横向于图像数据阵列。 来自图像数据阵列的图像用于重构目标的三维表示。 基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。 当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。 使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。 类似的技术估计图像平面内的运动以产生扩展的视场。

    Gated ultrasound imaging apparatus and method
    6.
    发明授权
    Gated ultrasound imaging apparatus and method 有权
    门式超声成像设备及方法

    公开(公告)号：US06626831B2

    公开(公告)日：2003-09-30

    申请号：US09767189

    申请日：2001-01-22

    申请人： Gregory L. Holley ,  Richard M. Bennett ,  Edward A. Gardner ,  Samuel H. Maslak

    发明人： Gregory L. Holley ,  Richard M. Bennett ,  Edward A. Gardner ,  Samuel H. Maslak

    IPC分类号： A61B800

    CPC分类号： A61B8/481 ,  A61B5/0456 ,  A61B8/543 ,  G01S7/52025 ,  G01S7/52038 ,  G01S7/52074 ,  G01S7/52085 ,  G01S7/52087 ,  G01S15/895

    摘要： An ultrasound imaging system is programmed to acquire first ultrasonic image frames intermittently. These first frames, typically triggered frames synchronized with a selected portion of an ECG cycle, are optimized for high image quality of a contrast agent included in the tissue. The imaging system automatically acquires second ultrasonic image frames between at least some of the first frames. The second image frames are typically locator frames which are optimized for reduced degradation of the contrast agent. More of the second frames are acquired per unit time than first frames, and both the first and second frames are displayed, either superimposed over one another or in side-by-side relationship. In this way the user is provided with substantially continuous transducer locating information, yet contrast agent destruction between acquisitions of the first, triggered frames is reduced or eliminated.

    摘要翻译： 超声成像系统被编程为间歇地获取第一超声图像帧。 这些第一帧，通常是与ECG周期的选定部分同步的触发帧，被优化用于组织中包括的造影剂的高图像质量。 成像系统在至少一些第一帧之间自动获取第二超声图像帧。 第二图像帧通常是定位器帧，其被优化用于造影剂的降低降低。 与第一帧相比，每单位时间获取更多的第二帧，并且显示第一和第二帧，或者彼此叠加或并排关系。 以这种方式，向用户提供基本上连续的换能器定位信息，但是减少或消除了第一触发帧的获取之间的造影剂破坏。

    Multiple ultrasound image registration system, method and transducer
    8.
    发明授权
    Multiple ultrasound image registration system, method and transducer 有权
    多重超声图像配准系统，方法和传感器

    公开(公告)号：US06201900B1

    公开(公告)日：2001-03-13

    申请号：US09340542

    申请日：1999-06-28

    申请人： John A. Hossack ,  John W. Sliwa, Jr. ,  Samuel H. Maslak ,  Edward A. Gardner ,  Gregory L. Holley ,  David J. Napolitano

    发明人： John A. Hossack ,  John W. Sliwa, Jr. ,  Samuel H. Maslak ,  Edward A. Gardner ,  Gregory L. Holley ,  David J. Napolitano

    IPC分类号： G06K900

    CPC分类号： A61B8/145 ,  A61B8/483 ,  G01S7/52034 ,  G01S7/52065 ,  G01S7/52071 ,  G01S7/52085 ,  G01S15/66 ,  G01S15/87 ,  G01S15/8934 ,  G01S15/8979 ,  G01S15/8993 ,  G06T7/246

    摘要： An ultrasonic imaging system includes an ultrasonic transducer having an image data array and a tracking array at each end of the image data array. The tracking arrays are oriented transversely to the image data array. Images from the image data array are used to reconstruct a three-dimensional representation of the target. The relative movement between respective frames of the image data is automatically estimated by a motion estimator, based on frames of data from the tracking arrays. As the transducer is rotated about the azimuthal axis of the image data array, features of the target remain within the image planes of the tracking arrays. Movements of these features in the image planes of the tracking arrays are used to estimate motion as required for the three-dimensional reconstruction. Similar techniques estimate motion within the plane of an image to create an extended field of view.

    摘要翻译： 超声波成像系统包括在图像数据阵列的每一端具有图像数据阵列和跟踪阵列的超声波换能器。 跟踪阵列横向于图像数据阵列。 来自图像数据阵列的图像用于重建目标的三维表示。 基于来自跟踪阵列的数据的帧，运动估计器自动地估计图像数据的各个帧之间的相对移动。 当传感器围绕图像数据阵列的方位角旋转时，目标的特征保持在跟踪阵列的图像平面内。 使用跟踪阵列的图像平面中的这些特征的运动来估计针对三维重建所需的运动。 类似的技术估计图像平面内的运动以产生扩展的视场。