公开(公告)号：US09778106B2

公开(公告)日：2017-10-03

申请号：US14794316

申请日：2015-07-08

Applicant: TECAN Trading AG

Inventor： Lutz Niggl ,  Andreas Erlbacher ,  Frank Münchow

IPC: G01J3/18 ,  G01J3/06 ,  G01J3/42 ,  G01N35/02 ,  G01N21/25 ,  G01N21/31 ,  G01J3/12

CPC classification number: G01J3/18 ,  G01J3/06 ,  G01J3/42 ,  G01J2003/1204 ,  G01J2003/1213 ,  G01J2003/1217 ,  G01N21/253 ,  G01N21/31 ,  G01N35/028 ,  G01N2021/3174 ,  G01N2201/084

Abstract: A spectrometer (1) comprises a light source (2), a monochromator (3) with at least one diffraction grating (4), a monochromator housing (5), an order sorting filter (7), a microplate receptacle (12) and a controller (6). The order sorting filter (7) of the spectrometer (1) comprises a substrate (23), a first optical thin film (24) and a second optical thin film (25), wherein, in a spatially partly overlapping and interference-free manner, the first optical thin film (24) is arranged on a first surface (26) and the second optical thin film (25) is arranged on a second surface (27) of the substrate (23). A spectrometer (1) equipped with a respective order sorting filter is used in a scanning method for detecting the absorption spectrum of samples examined in wells (14) of microplates (13).

公开(公告)号：US11442260B2

公开(公告)日：2022-09-13

申请号：US16041922

申请日：2018-07-23

Applicant: TECAN TRADING AG

Inventor： Andreas Erlbacher ,  Markus Schürf ,  Josef Grassl ,  Alexander Kaser

IPC: G02B21/00 ,  G02B7/36 ,  G02B7/32 ,  G02B21/24 ,  G02B21/06 ,  G02B21/36

Abstract: A system 100 and method are provided for imaging a sample in a sample holder. For providing autofocus, a 2D pattern is projected onto the sample holder 050 via an astigmatic optical element 120. Image data 172 of the sample is acquired by an image sensor 140 via magnification optics 150. A difference in sharpness of the two-dimensional pattern in the image data is measured along a first axis and a second axis. Based on the difference, a magnitude and direction of defocus of the camera subsystem is determined with respect to the sample holder. This enables the sample holder, and thereby the sample, to be brought into focus in a fast and reliable manner.