公开(公告)号：US11559804B2

公开(公告)日：2023-01-24

申请号：US16173102

申请日：2018-10-29

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Yoichi Makino ,  Akihiro Hoshino ,  Tomoko Kunitomi ,  Keisuke Goto ,  Yosuke Horiuchi

IPC: G01N21/64 ,  B01L3/00 ,  B01L7/00

Abstract: An analysis apparatus including a stage, an analysis device placed on the stage and including receiving sections which accommodate a sample and a reagent for biochemical reaction, and are communicated with one another through a flow path having an inlet and an outlet, a liquid introduction section which is connected to the inlet and supplies into the flow path the sample, the reagent, and an sealing liquid for sealing each of the receiving sections, and a waste liquid storage section which is connected to the outlet and stores as waste liquid an excess of the sample and the reagent and a part of the sealing liquid supplied to the flow path, an optical system which includes an objective lens, emits excitation light to the receiving sections and allows observation of fluorescence generated in the receiving sections by the excitation light, and a control unit that controls such that the sealing liquid and the excess of the sample and the reagent form an interface in the waste liquid storage section, and that the interface is formed at a distance not less than a fluorescence-obtainable distance from a bottom of the receiving sections.

公开(公告)号：US11898194B2

公开(公告)日：2024-02-13

申请号：US16872855

申请日：2020-05-12

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Takumi Hirase ,  Yoichi Makino ,  Yosuke Horiuchi

IPC: C12Q1/68 ,  C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N33/536

CPC classification number: C12Q1/6806 ,  B01L3/5027 ,  C12Q1/686 ,  G01N33/536 ,  B01L2200/0689 ,  B01L2300/0829

Abstract: A method for detecting a target molecule, including supplying a liquid dispersion of a structural substance including a target molecule into a well array such that the structural substance is introduced into wells of the well array, supplying a sealing solution into the well array such that a layer of the sealing solution is formed on the liquid dispersion in the wells, and that the liquid dispersion is sealed in the wells, extracting the target molecule from the structural substance, and detecting the target molecule.