专利检索 ap:("Takehiko Yamane" OR "Takuji Hashizume" OR "Katsuji Yamashita" OR "Kazunori Hosoe" OR "Fumiyuki Kuze" OR "Kiyoshi Watanabe") AND inv:"Takuji Hashizume" 第 1 页

1.

发明授权
3'-hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same 失效
标题翻译： 3'-羟基苯并恶嗪利福霉素衍生物，其制备方法和含有该抗体的抗菌剂

公开(公告)号：US4983602A

公开(公告)日：1991-01-08

申请号：US407995

申请日：1989-09-14

申请人： Takehiko Yamane , Takuji Hashizume , Katsuji Yamashita , Kazunori Hosoe , Fumiyuki Kuze , Kiyoshi Watanabe

发明人： Takehiko Yamane , Takuji Hashizume , Katsuji Yamashita , Kazunori Hosoe , Fumiyuki Kuze , Kiyoshi Watanabe

IPC分类号： C07D498/18

CPC分类号： C07D498/18

摘要： A rifamycin derivative having the formula (I): ##STR1## wherein A is a group having the formula: ##STR2## in which R.sup.1 is an alkyl group having 4 or 5 carbon atoms or an alkenyl group having 3 to 5 carbon atoms, or a group having the formula: in which n is 3 or 4; or a pharmaceutically acceptable salt thereof. The rifamycin derivative (I) exhibits a strong antibacterial activity against Gram-positive bacteria and acid-fast bacteria, and also exhibits a strong antibacterial activity against tubercle bacilli.

2.

发明授权
Substituted benzoxazinorifamycin derivative and antibacterial agent containing the same 失效
标题翻译：取代的苯并恶嗪利霉素衍生物和含有它们的抗菌剂

公开(公告)号：US4965261A

公开(公告)日：1990-10-23

申请号：US324499

申请日：1989-03-16

申请人： Fumihiko Kanoo , Takehiko Yamane , Hideo Kondo , Takuji Hashizume , Katsuji Yamashita , Kazunori Hosoe , Fumiyuki Kuze , Kiyoshi Watanabe

发明人： Fumihiko Kanoo , Takehiko Yamane , Hideo Kondo , Takuji Hashizume , Katsuji Yamashita , Kazunori Hosoe , Fumiyuki Kuze , Kiyoshi Watanabe

IPC分类号： C07D498/18

CPC分类号： C07D498/18

摘要： A rifamycin derivative having the formula (I): ##STR1## wherein R.sup.1 is hydrogen atom, methyl group or ethyl group, R.sup.2 is an alkyl group having 1 to 4 carbon atoms, and A is a group having the formula: ##STR2## in which n is an integer of 3 to 5, or group having the formula: ##STR3## in which R.sup.3 is a alkyl group having 1 to 5 carbon atoms; or a salt thereof. The rifamycin derivative (I) exhibits a strong antibacterial activity against Gram-positive bacteria and acid-fast bacteria, and also exhibits a strong antibacterial activity against tubercle bacilli.

3.

发明授权
Benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same 失效
标题翻译：苯并恶嗪利霉素衍生物，其制备方法和含有它们的抗菌剂

公开(公告)号：US4690919A

公开(公告)日：1987-09-01

申请号：US826398

申请日：1986-02-05

申请人： Takehiko Yamane , Takuji Hashizume , Katsuji Yamashita , Kiyoshi Watanabe

发明人： Takehiko Yamane , Takuji Hashizume , Katsuji Yamashita , Kiyoshi Watanabe

IPC分类号： C07D498/18 , C07D519/00 , A61K31/535

CPC分类号： C07D498/18 , C07D519/00

摘要： A novel rifamycin derivative having the general formula (I): ##STR1## or salts thereof, a process for preparing the same and antibacterial agents containing the same as an effective component.The rifamycin derivative of the present invention having the general formula (I) shows a strong antibacterial activity against the Gram-positive bacteria and the acid-fast bacteria.

摘要翻译： 具有通式（I）的新型利福霉素衍生物或其盐，其制备方法和含有该有效成分的抗菌剂。具有通式（I）的本发明的利福霉素衍生物显示出对革兰氏阳性菌和耐酸细菌的强抗菌活性。