公开(公告)号：US20240043400A1

公开(公告)日：2024-02-08

申请号：US18265156

申请日：2021-12-01

Applicant: UCB Biopharma SRL

Inventor： Ali Ates ,  Pierre Burssens ,  Adrian Hall ,  Laurent Provins ,  David Skolc ,  Anne Valade

IPC: C07D401/06 ,  C07D217/04 ,  C07D471/04 ,  C07D401/10

CPC classification number: C07D401/06 ,  C07D217/04 ,  C07D471/04 ,  C07D401/10

Abstract: The present invention relates to octahydroisoquinolinyl derivatives according to formula (I), which are Positive Allosteric Modulators of D1 and accordingly of benefit as pharmaceutical agents for the treatment of diseases in which D1 receptors play a role.