公开(公告)号：US20200369675A1

公开(公告)日：2020-11-26

申请号：US16767896

申请日：2018-11-27

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Anne Valade ,  Celine Vermeiren ,  Martyn Wood ,  Ralph Macquire

IPC: C07D491/048 ,  C07B59/00 ,  A61K51/04

Abstract: The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.

公开(公告)号：US20240043400A1

公开(公告)日：2024-02-08

申请号：US18265156

申请日：2021-12-01

Applicant: UCB Biopharma SRL

Inventor： Ali Ates ,  Pierre Burssens ,  Adrian Hall ,  Laurent Provins ,  David Skolc ,  Anne Valade

IPC: C07D401/06 ,  C07D217/04 ,  C07D471/04 ,  C07D401/10

CPC classification number: C07D401/06 ,  C07D217/04 ,  C07D471/04 ,  C07D401/10

Abstract: The present invention relates to octahydroisoquinolinyl derivatives according to formula (I), which are Positive Allosteric Modulators of D1 and accordingly of benefit as pharmaceutical agents for the treatment of diseases in which D1 receptors play a role.

公开(公告)号：US20220251064A1

公开(公告)日：2022-08-11

申请号：US17621871

申请日：2020-06-29

Applicant: UCB Biopharma SRL

Inventor： Anne Valade

IPC: C07D401/06

Abstract: The present invention relates to compounds according to formula (I), which are a positive allosteric modulators of D1 and accordingly of benefit as pharmaceutical agents for the treatment of diseases in which D1 receptors play a role.

公开(公告)号：US20220162221A1

公开(公告)日：2022-05-26

申请号：US17534711

申请日：2021-11-24

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Anne Valade ,  Celine Vermeiren ,  Martyn Wood ,  Ralph Maquire

IPC: C07D491/048 ,  A61K51/04 ,  C07B59/00

Abstract: The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.

公开(公告)号：US20240343737A1

公开(公告)日：2024-10-17

申请号：US18632964

申请日：2024-04-11

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Anne Valade ,  Celine Vermeiren ,  Martyn Wood ,  Ralph Macquire

IPC: C07D491/048 ,  A61K51/04 ,  C07B59/00

CPC classification number: C07D491/048 ,  A61K51/0459 ,  C07B59/002 ,  C07B2200/05

Abstract: The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.