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1.发明申请Apparatuses for thermal management of actuated probes, such as catheter distal ends 审中-公开用于致动探针（例如导管远端）的热管理的装置公开(公告)号：US20070167826A1
公开(公告)日：2007-07-19
申请号：US11330378
申请日：2006-01-11
IPC分类号： A61B8/14
CPC分类号： A61B8/4461 , A61B5/0084 , A61B8/12 , A61B8/445 , A61B8/546
摘要： Alternative embodiments are provided, for use individually or in combination, for thermal management of catheter distal ends and other types of probes such as may be used in catheter and other instruments' diagnostic and interventional devices. In an exemplary embodiment, a catheter distal end (1000) comprises an ultrasound imaging assembly (1003) that comprises an actuator (1004), a drive shaft (1006), a section (1008) of an interconnect (1010), and a transducer assembly (1009). A circulation fin (1018) optionally may be affixed to the bottom (1016) of transducer assembly (1009), and extends into a defined space (1017) to enhance circulation of acoustic transmission medium that is in the defined space (1017). This disperses heat from the actuator (1004) and the transducer assembly (1009). A similar fin (1018) may also, or alternatively, be positioned on the section (1008) of interconnect (1010). Other thermal management approaches also are disclosed.
摘要翻译： 提供替代实施例，用于单独地或组合地用于导管远端的热管理和其它类型的探针，例如可以用于导管和其他器械的诊断和介入装置中。 在示例性实施例中，导管远端（1000）包括超声成像组件（1003），其包括致动器（1004），驱动轴（1006），互连（1010）的部分（1008）和换能器 装配（1009）。 循环翅片（1018）可任选地附接到换能器组件（1009）的底部（1016），并且延伸到限定的空间（1017）中以增强在限定空间（1017）中的声学传播介质的循环。 这样分散来自致动器（1004）和换能器组件（1009）的热量。 类似的翅片（1018）也可以或替代地定位在互连（1010）的部分（1008）上。 还公开了其他热管理方法。
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公开(公告)号：US20070073135A1
公开(公告)日：2007-03-29
申请号：US11276258
申请日：2006-02-21
IPC分类号： A61B5/05
CPC分类号： G01S15/899 , A61B5/042 , A61B8/08 , A61B8/0883 , A61B8/12 , A61B8/4254 , A61B8/445 , A61B8/4472 , A61B8/4483 , A61B8/4488 , A61B8/463 , A61B8/483 , A61B8/485 , A61B17/2202 , A61B17/2256 , A61B2090/3782 , A61N7/022 , G01S15/8918 , G01S15/8925 , G01S15/895
摘要： A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. In addition, the system includes a medical imaging system operationally coupled to the catheter and having a display area and a user interface area, wherein the medical imaging system is configured to facilitate defining a therapy pathway to facilitate delivering therapy to the one or more regions of interest.
摘要翻译： 提出了一种用于对一个或多个感兴趣区域进行成像和提供治疗的系统。 该系统包括成像和治疗导管，其构造成对解剖区域进行成像，以便于评估在解剖区域内的一个或多个区域中的治疗需要，并将解决方案区域内的一个或多个感兴趣区域递送治疗。 此外，该系统包括可操作地耦合到导管并具有显示区域和用户界面区域的医学成像系统，其中医学成像系统被配置为有助于限定治疗路径，以促进将治疗递送到一个或多个区域 利益。
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公开(公告)号：US20070129633A1
公开(公告)日：2007-06-07
申请号：US11276259
申请日：2006-02-21
IPC分类号： A61B8/00
CPC分类号： A61N7/022 , A61B8/06 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/483 , A61B8/485 , A61B2017/00243 , A61B2090/3782 , A61N2007/0078 , A61N2007/0082
摘要： A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. The catheter includes a therapy device having a plurality of independently controllable therapy elements. The independence of the therapy elements is exploited when multiple regions are to receive therapy simultaneously or at a given catheter position within a subject.
摘要翻译： 提出了一种用于对一个或多个感兴趣区域进行成像和提供治疗的系统。 该系统包括成像和治疗导管，其构造成对解剖区域进行成像，以便于评估在解剖区域内的一个或多个区域中的治疗需要，并将解决方案区域内的一个或多个感兴趣区域递送治疗。 导管包括具有多个可独立控制的治疗元件的治疗装置。 当多个区域同时接收治疗或在受试者内的给定导管位置时，治疗元件的独立性被利用。
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公开(公告)号：US20080139893A1
公开(公告)日：2008-06-12
申请号：US11608294
申请日：2006-12-08
IPC分类号： A61B5/00
CPC分类号： A61B7/04 , A61B2562/0204 , A61B2562/046
摘要： An apparatus and system for sensing body sounds of a subject is described. The apparatus includes a flexible sheet for conformally contacting at least a portion of a subject's body surface proximate a body region generating body sounds. The apparatus also includes a plurality of acoustic sensors formed in the sheet for sensing body sounds from the subject and generating respective signals indicative of the sensed body sounds.
摘要翻译： 描述了用于感测被摄体的身体声音的装置和系统。 该装置包括柔性片，用于在接近生物身体声音的身体区域之间保形接触被摄体的身体表面的至少一部分。 该装置还包括形成在片材中的多个声学传感器，用于感测来自被摄体的身体声音，并产生指示感测到的身体声音的各个信号。
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公开(公告)号：US20090076390A1
公开(公告)日：2009-03-19
申请号：US12327171
申请日：2008-12-03
CPC分类号： A61N7/022 , A61B8/06 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/483 , A61B8/485 , A61B2017/00243 , A61B2090/3782 , A61N2007/0078 , A61N2007/0082
摘要： A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. In addition, the system includes a medical imaging system operationally coupled to the catheter and having a display area and a user interface area, wherein the medical imaging system is configured to facilitate defining a therapy pathway to facilitate delivering therapy to the one or more regions of interest.
摘要翻译： 提出了一种用于对一个或多个感兴趣区域进行成像和提供治疗的系统。 该系统包括成像和治疗导管，其构造成对解剖区域进行成像，以便于评估在解剖区域内的一个或多个区域中的治疗需要，并将解决方案区域内的一个或多个感兴趣区域递送治疗。 此外，该系统包括可操作地耦合到导管并具有显示区域和用户界面区域的医学成像系统，其中医学成像系统被配置为有助于限定治疗路径，以促进将治疗递送到一个或多个区域 利益。
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公开(公告)号：US07766833B2
公开(公告)日：2010-08-03
申请号：US11276259
申请日：2006-02-21
CPC分类号： A61N7/022 , A61B8/06 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/483 , A61B8/485 , A61B2017/00243 , A61B2090/3782 , A61N2007/0078 , A61N2007/0082
摘要： A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. The catheter includes a therapy device having a plurality of independently controllable therapy elements. The independence of the therapy elements is exploited when multiple regions are to receive therapy simultaneously or at a given catheter position within a subject.
摘要翻译： 提出了一种用于对一个或多个感兴趣区域进行成像和提供治疗的系统。 该系统包括成像和治疗导管，其构造成对解剖区域进行成像，以便于评估在解剖区域内的一个或多个区域中的治疗需要，并将解决方案区域内的一个或多个感兴趣区域递送治疗。 导管包括具有多个可独立控制的治疗元件的治疗装置。 当多个区域同时接收治疗或在受试者内的给定导管位置时，治疗元件的独立性被利用。
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7.发明申请Apparatus for catheter tips, including mechanically scanning ultrasound probe catheter tip 审中-公开用于导管尖端的装置，包括机械扫描超声探头导管尖端公开(公告)号：US20070167825A1
公开(公告)日：2007-07-19
申请号：US11330377
申请日：2006-01-11
申请人： Warren Lee , Douglas Wildes , George Sogoian , Charles Baumgartner , Weston Griffin , Mark Langer
发明人： Warren Lee , Douglas Wildes , George Sogoian , Charles Baumgartner , Weston Griffin , Mark Langer
IPC分类号： A61B8/14
CPC分类号： A61B8/4461 , A61B8/12 , A61B8/4411 , A61B8/445
摘要： A catheter tip (50, 170) is provided that is adapted for mating attachment to a catheter body (90, 300). In an embodiment, the catheter tip (50,170) comprises a transducer array (32, 60, 110, 210) in electrical communication with an interconnect (120, 220) and in a mechanical driven relationship with an actuator (80), also in the catheter tip (50, 170), via a drive shaft (38, 82). Oscillating back and forth motion of the transducer array (32, 60, 110, 210) provides ultrasonic imaging functionality that may include real time three-dimensional imaging. Other embodiments of the catheter tip (50, 170) and methods of fabrication also are provided.
摘要翻译： 提供导管尖端（50,170），其适于与导管主体（90,300）配合。 在一个实施例中，导管尖端（50,170）包括与互连（120,220）电连通并且与致动器（80）机械驱动关系的换能器阵列（32,60,110,210），也在 导管尖端（50,170），经由驱动轴（38,82）。 振荡器阵列（32,60,110,210）的来回摆动提供可包括实时三维成像的超声成像功能。 还提供了导管尖端（50,170）的其它实施例和制造方法。
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公开(公告)号：US20070157732A1
公开(公告)日：2007-07-12
申请号：US11327779
申请日：2006-01-06
CPC分类号： G10K11/002 , A61B8/12 , A61B8/445 , B06B1/0629 , G10K11/34
摘要： A composite structure of a z-axis interconnect is presented. The composite structure includes a plurality of layers of backing material alternatingly arranged between a plurality of interconnect layers, where the plurality of interconnect layers is configured to facilitate coupling the composite structure of the z-axis interconnect to a transducer array, where the composite structure of z-axis interconnect is configured for use in an invasive probe.
摘要翻译： 介绍了z轴互连的复合结构。 复合结构包括交替布置在多个互连层之间的多层背衬材料，其中多个互连层被配置为便于将z轴互连的复合结构耦合到换能器阵列，其中复合结构 z轴互连配置用于侵入性探针。
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9.发明申请Apparatuses Comprising Catheter Tips, Including Mechanically Scanning Ultrasound Probe Catheter Tip 有权包括导管提示，包括机械扫描超声探头导管尖端的装置公开(公告)号：US20070167813A1
公开(公告)日：2007-07-19
申请号：US11624344
申请日：2007-01-18
申请人： Warren Lee , Weston Griffin , Douglas Wildes
发明人： Warren Lee , Weston Griffin , Douglas Wildes
IPC分类号： A61B8/14
CPC分类号： A61B8/4461 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B8/483
摘要： A catheter tip (50, 170, 750) is provided that is adapted for mating attachment to a catheter body (90, 300, 790). In an embodiment, the catheter tip (50, 170, 750) comprises a transducer array (32, 60, 110, 210, 710) in electrical communication with an interconnect (120, 220, 720) and in a mechanical driven relationship with an actuator (80, 730), also in the catheter tip (50, 170, 750), via a drive shaft (38, 82, 732). The transducer array (710) is encapsulated in a potting material body 711 providing a desired ultrasound acoustical transmission, A defined annular space 761 exists between an outer capsule 752 of the catheter tip 750 and the potting material body 711. Oscillating back and forth motion of the transducer array (32, 60, 110, 210, 710) provides ultrasonic imaging functionality that may include real time three-dimensional imaging. Other embodiments of the catheter tip (50, 170, 750) and methods of fabrication also are provided.
摘要翻译： 提供了适于与导管主体（90,300,790）配合的导管尖端（50,170,750）。 在一个实施例中，导管尖端（50,170,750）包括与互连（120,220,720）电连通并且与机械驱动关系的换能器阵列（32,60,110,210,710） 致动器（80,730），也通过驱动轴（38,82,732）在导管尖端（50,170,750）中。 换能器阵列（710）被封装在灌封材料主体711中，提供期望的超声波传播。在导管末端750的外部胶囊752和灌封材料主体711之间存在限定的环形空间761。 振荡器阵列（32,60,110,210,710）的前后运动提供可包括实时三维成像的超声成像功能。 还提供了导管尖端（50,170,750）的其它实施例和制造方法。
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10.发明申请Method of manufacture of catheter tips, including mechanically scanning ultrasound probe catheter tip, and apparatus made by the method 审中-公开导管尖端的制造方法，包括机械扫描超声探头导管尖端，以及由该方法制成的装置公开(公告)号：US20070167824A1
公开(公告)日：2007-07-19
申请号：US11329815
申请日：2006-01-11
申请人： Warren Lee , Douglas Wildes , George Sogoian , Charles Baumgartner , Weston Griffin , Mark Langer
发明人： Warren Lee , Douglas Wildes , George Sogoian , Charles Baumgartner , Weston Griffin , Mark Langer
IPC分类号： A61B8/14
CPC分类号： A61B8/4461 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B17/2202 , A61B18/1492 , A61M25/001 , A61M25/0069 , A61M25/008 , A61M25/0082 , G10K11/352
摘要： A method to fabricate a catheter tip that encapsulates a mechanically actuated ultrasound transducer assembly is provided. In a representative procedure, the steps include providing an ultrasound transducer assembly (100) adapted for use with a catheter (300), the ultrasound transducer assembly (100) comprising a proximal end (102) and a distal end (104), a drive linkage (132) to an actuator (130), and a transducer array (110), the transducer array (110) electrically connected to an interconnect (120) adapted for passage to or through a body of the catheter (300), connecting the actuator (130), adapted for use with the ultrasound transducer assembly (100), to the drive linkage (132); and inserting the ultrasound transducer assembly (100) and the actuator (132) into a polymer or a plastic type or reinforced polymer sheath (140) comprising an acoustically transparent section, a closed end (142) at its distal end and an open end (144) at its proximal end, wherein the polymer sheath (140) provides a defined rigidity.
摘要翻译： 提供了一种制造封装机械致动的超声换能器组件的导管尖端的方法。 在代表性的程序中，步骤包括提供适于与导管（300）一起使用的超声换能器组件（100），超声换能器组件（100）包括近端（102）和远端（104），驱动器 连接（132）到致动器（130），以及换能器阵列（110），所述换能器阵列（110）电连接到适于通向导管（300）的主体或通过导管（300）的主体的互连（120） 致动器（130），适于与超声换能器组件（100）一起使用于驱动连杆机构（132）; 以及将所述超声换能器组件（100）和所述致动器（132）插入聚合物或塑料型或增强的聚合物护套（140）中，所述聚合物护套包括声透明部分，在其远端处的封闭端（142）和开口端 144）在其近端处，其中所述聚合物护套（140）提供限定的刚性。
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