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公开(公告)号：US20240360239A1
公开(公告)日：2024-10-31
申请号：US18644984
申请日：2024-04-24
发明人： Hergen SPITS , Paula Maria Wilhelmina VAN HELDEN , Remko SCHOTTE , Wouter POS , Christien FATMAWATI , Danïel Michiel GO , Koen WAGNER , Julien Christian VILLAUDY
IPC分类号： C07K16/28 , A61K39/00 , A61P35/00 , C07K14/705 , G01N33/574
CPC分类号： C07K16/2896 , A61P35/00 , C07K14/70596 , C07K16/2818 , G01N33/57492 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/34 , C07K2317/54 , C07K2317/73 , C07K2317/732 , C07K2317/734 , G01N2333/70596
摘要： The present invention provides novel binding compounds and therapeutic applications thereof.
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公开(公告)号：US20230235018A1
公开(公告)日：2023-07-27
申请号：US18050272
申请日：2022-10-27
发明人： Hergen SPITS , Marijn Aletta GILLISSEN , Martijn KEDDE , Mette Deborah HAZENBERG , Paula Maria Wilhelmina VAN HELDEN , Wouter POS
IPC分类号： C07K14/705 , C07K14/435 , C07K16/28 , G01N33/574
CPC分类号： C07K14/70596 , C07K14/435 , C07K16/2896 , G01N33/57426 , A61K38/00
摘要： The present invention provides novel compounds comprising an antigen of AML cells, and uses thereof.
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公开(公告)号：US12084681B2
公开(公告)日：2024-09-10
申请号：US16575518
申请日：2019-09-19
CPC分类号： C12N5/0635 , C07K16/00 , C07K16/1018 , C12N15/86 , C12P21/005 , C07K2317/14 , C12N2510/00 , C12N2510/02 , C12N2510/04 , C12N2740/13045 , C12N2810/6054
摘要： The present invention provides means and methods for producing improved ex vivo B cell cultures with a short doubling time.
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公开(公告)号：US11999793B2
公开(公告)日：2024-06-04
申请号：US17476650
申请日：2021-09-16
发明人： Hergen Spits , Paula Maria Wilhelmina Van Helden , Remko Schotte , Wouter Pos , Christien Fatmawati , Danïel Michiel Go , Koen Wagner , Julien Christian Villaudy
IPC分类号： C07K16/28 , A61P35/00 , C07K14/705 , G01N33/574 , A61K39/00
CPC分类号： C07K16/2896 , A61P35/00 , C07K14/70596 , C07K16/2818 , G01N33/57492 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/34 , C07K2317/54 , C07K2317/73 , C07K2317/732 , C07K2317/734 , G01N2333/70596
摘要： The present invention provides novel binding compounds and therapeutic applications thereof.
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5.发明公开公开(公告)号：US20230242667A1
公开(公告)日：2023-08-03
申请号：US18172417
申请日：2023-02-22
发明人： Hergen SPITS , Tim BEAUMONT , Marijn Aletta GILLISSEN , Adrianus Quirinus BAKKER , Mette Deborah HAZENBERG , Martijn KEDDE
CPC分类号： C07K16/3061 , C07K16/06 , A61K47/6851 , C07K16/40 , C12P21/005 , G01N33/57492 , C07K2317/21 , C07K2317/33 , C07K2317/73 , C07K2317/565 , C07K2317/732 , C07K2317/734 , G01N2333/705
摘要： The invention provides human AML-specific binding compounds that are able to bind a cell surface component of AML cells. Therapeutic uses of binding compounds against AML are also provided.
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公开(公告)号：US11629200B2
公开(公告)日：2023-04-18
申请号：US16733376
申请日：2020-01-03
发明人： Hergen Spits , Tim Beaumont , Marijn Aletta Gillissen , Adrianus Quirinus Bakker , Mette Deborah Hazenberg , Martijn Kedde
摘要： The invention provides human AML-specific binding compounds that are able to bind a cell surface component of AML cells. Therapeutic uses of binding compounds against AML are also provided.
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公开(公告)号：US11524989B2
公开(公告)日：2022-12-13
申请号：US15737924
申请日：2016-06-24
发明人： Hergen Spits , Marijn Aletta Gillissen , Martijn Kedde , Mette Deborah Hazenberg , Paula Maria Wilhelmina van Helden , Wouter Pos
IPC分类号： C07K14/435 , C07K14/705 , C07K16/28 , G01N33/574 , A61K38/00
摘要： The present invention provides novel compounds comprising an antigen of AML cells, and uses thereof.
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公开(公告)号：US20240317880A1
公开(公告)日：2024-09-26
申请号：US17789940
申请日：2021-01-08
发明人： Tim BEAUMONT , Sabrina Julia Louisa MERAT , Mark Jeroen KWAKKENBOS , Martijn KEDDE , Hergen SPITS
IPC分类号： C07K16/28 , A61K39/00 , A61K47/68 , C07K16/22 , C12N5/0783
CPC分类号： C07K16/2896 , A61K47/6803 , C07K16/22 , C07K16/2809 , C12N5/0636 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/77 , C07K2317/92
摘要： The present invention relates to epithelial cadherin-specific antibodies, as well as uses thereof in the diagnosis and treatment of diseases such as cancer.
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