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Patent Agency Ranking
公开(公告)号：US20150111890A1
公开(公告)日：2015-04-23
申请号：US14395628
申请日：2013-04-19
Applicant: AbbVie Inc.
Inventor： Lisa A. Hasvold , Dachun Liu , Chang Hoon Park , John K. Pratt , George S. Sheppard , Le Wang
IPC: C07D409/12 , A61K31/4035 , C07D403/04 , A61K31/404 , C07D405/04 , A61K31/416 , C07D405/10 , A61K31/5377 , C07D401/12 , A61K31/4439 , A61K31/4709 , C07D403/12 , C07D209/44 , A61K31/4184
CPC classification number: C07D409/12 , A61K31/4035 , A61K31/404 , A61K31/416 , A61K31/4184 , A61K31/427 , A61K31/4439 , A61K31/4709 , A61K31/5377 , A61K45/06 , C07D209/44 , C07D209/48 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D405/12 , C07D409/10 , C07D417/12
Abstract: The present invention provides for compounds of formula (I) wherein A, Y, J, R1, R2, and R3 have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof,that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, diabetes, obesity, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中A，Y，J，R 1，R 2和R 3具有说明书中定义的任何值及其药学上可接受的盐，其可用作治疗 疾病和病症，包括炎性疾病，糖尿病，肥胖症，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
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公开(公告)号：US08980879B2
公开(公告)日：2015-03-17
申请号：US14203651
申请日：2014-03-11
Applicant: AbbVie Inc.
Inventor： Dachun Liu , John Pratt , Le Wang , Lisa A. Hasvold , Andrew Bogdan
IPC: C07D471/04 , C07D487/04 , A61K31/407 , A61K31/437 , A61K31/5025 , A61K31/519 , A61K31/18 , C07D471/16 , C07D471/12 , C07D471/22
CPC classification number: A61K31/55 , C07D471/12 , C07D471/16 , C07D471/22 , Y02A50/463
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R1，R2，R6，Y1，Y2，A1，A2，A3和A4具有说明书中定义的任何值及其药学上可接受的盐，其可用作 治疗疾病和病症的药剂，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
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公开(公告)号：US20140275026A1
公开(公告)日：2014-09-18
申请号：US14206028
申请日：2014-03-12
Applicant: AbbVie Inc.
Inventor： Le Wang , John Pratt , Lisa A. Hasvold , Dachun Liu , Yujia Dai , Steven D. Fidanze , James H. Holms , Robert A. Mantei , Keith F. McDaniel , George S. Sheppard , William J. McClellan
IPC: C07D471/04
CPC classification number: C07D471/04 , C07D519/00
Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, and R5 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
Abstract translation: 本发明提供式（I）化合物，其中R 1，R 2，R 3，R 4和R 5具有说明书中定义的任何值及其药学上可接受的盐，其可用作治疗疾病和病症的试剂 ，包括炎性疾病，癌症和艾滋病。 还提供了包含一种或多种式（I）化合物的药物组合物。
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94.发明申请公开(公告)号：US20140113910A1
公开(公告)日：2014-04-24
申请号：US14038409
申请日：2013-09-26
Inventor： Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa A. Hasvold , Laura Hexamer , Aaron R. Kunzer , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt , Robert A. Mantei , Todd M. Hansen
IPC: C07D471/04 , A61K31/496
CPC classification number: C07D401/12 , A61K31/496 , C07D209/82 , C07D401/14 , C07D403/12 , C07D471/04 , C07D519/00 , Y02A50/463
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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95.发明申请公开(公告)号：US20140057890A1
公开(公告)日：2014-02-27
申请号：US14058164
申请日：2013-10-18
Applicant: AbbVie Inc.
Inventor： Milan Bruncko , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura A. Hexamer , Aaron R. Kunzer , Robert A. Mantei , William J. McClellan , Chang H. Park , Cheol-Min Park , Andrew M. Petros , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt
IPC: A61K31/5377 , A61K31/496 , C07D413/06 , C07D401/06 , A61K45/06 , A61K31/407 , C07D403/06 , A61K31/501 , C07D241/04 , A61K31/495 , C07D405/06 , C07D487/04
CPC classification number: C07D401/12 , A61K31/407 , A61K31/495 , A61K31/496 , A61K31/501 , A61K31/5377 , A61K45/06 , C07D209/08 , C07D209/32 , C07D211/58 , C07D211/96 , C07D213/64 , C07D215/20 , C07D217/16 , C07D231/56 , C07D235/26 , C07D241/04 , C07D249/04 , C07D295/125 , C07D295/14 , C07D295/155 , C07D309/04 , C07D309/14 , C07D401/06 , C07D403/06 , C07D405/06 , C07D405/12 , C07D405/14 , C07D413/06 , C07D417/12 , C07D471/04 , C07D487/04
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.
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