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公开(公告)号:US07417116B2
公开(公告)日:2008-08-26
申请号:US10219062
申请日:2002-08-12
申请人: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
发明人: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
CPC分类号: C07K14/705 , C07K14/47 , G01N33/574
摘要: The present invention is directed to novel PRO7155 polypeptides and chimeric polypeptide molecules comprising PRO7155 polypeptides fused to heterologous polypeptide sequences.
摘要翻译: 本发明涉及新颖的PRO7155多肽和包含与异源多肽序列融合的PRO7155多肽的嵌合多肽分子。
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公开(公告)号:US07429641B2
公开(公告)日:2008-09-30
申请号:US10218956
申请日:2002-08-12
申请人: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
发明人: Kevin P. Baker , Luc Desnoyers , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean-Philippe F. Stephan , Colin K. Watanabe , William I. Wood
CPC分类号: C07K14/705 , C07K14/47 , G01N33/574
摘要: The present invention is directed to novel PRO9830 polypeptides chimeric polypeptide molecules comprising PRO9830 polypeptides fused to heterologous polypeptide sequences.
摘要翻译: 本发明涉及包含与异源多肽序列融合的PRO9830多肽的新型PRO9830多肽嵌合多肽分子。
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公开(公告)号:US07087738B2
公开(公告)日:2006-08-08
申请号:US09907942
申请日:2001-07-17
申请人: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
发明人: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
CPC分类号: C07K14/705 , C07K14/47
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US06965011B2
公开(公告)日:2005-11-15
申请号:US09905449
申请日:2001-07-13
申请人: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
发明人: David Botstein , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
IPC分类号: C07K14/435 , C07K14/47 , C07K14/705 , C07K19/00
CPC分类号: C07K14/705 , C07K14/47
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07368558B2
公开(公告)日:2008-05-06
申请号:US10899671
申请日:2004-07-27
申请人: David Botstein , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
发明人: David Botstein , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Margaret Ann Roy , William I. Wood
CPC分类号: C07K14/47 , C07K14/705
摘要: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译: 本发明涉及分泌和跨膜多肽以及编码这些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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96.
公开(公告)号:US06929947B2
公开(公告)日:2005-08-16
申请号:US09944944
申请日:2001-08-31
申请人: David Botstein , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Margaret Ann Roy , William I. Wood
发明人: David Botstein , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Margaret Ann Roy , William I. Wood
CPC分类号: C07K14/47 , A61K38/1709
摘要: The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译: 本发明涉及编码抑制肿瘤细胞中肿瘤生长的分泌多肽的核酸。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号:US07294695B2
公开(公告)日:2007-11-13
申请号:US10243189
申请日:2002-09-12
申请人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
IPC分类号: C07K14/00
CPC分类号: C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号:US07452975B2
公开(公告)日:2008-11-18
申请号:US10243167
申请日:2002-09-12
申请人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
CPC分类号: C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号:US07297770B2
公开(公告)日:2007-11-20
申请号:US10243364
申请日:2002-09-12
申请人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
IPC分类号: C07K14/00
CPC分类号: C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods, for producing the polypeptides of the present invention.
摘要翻译: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含这些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明多肽的嵌合多肽分子,与本发明多肽结合的抗体以及用于产生本发明多肽的方法 本发明。
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公开(公告)号:US07294696B2
公开(公告)日:2007-11-13
申请号:US10243345
申请日:2002-09-12
申请人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
发明人: Kevin P. Baker , Dan L. Eaton , Ellen Filvaroff , Audrey Goddard , J. Christopher Grimaldi , Austin L. Gurney , Victoria Smith , Jean Philippe Stephan , Colin K. Watanabe , William I. Wood , Zemin Zhang , Sherman Fong
IPC分类号: C07K14/00
CPC分类号: C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞,包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子,与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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