公开(公告)号：US08132695B2

公开(公告)日：2012-03-13

申请号：US11938144

申请日：2007-11-09

Applicant: Daniel Py ,  Beniot Adamo

Inventor： Daniel Py ,  Beniot Adamo

IPC: B65D37/00

CPC classification number: B65D83/0033 ,  A61F9/0008 ,  B05B11/0027 ,  B05B11/007 ,  B05B11/0097 ,  B05B11/3032 ,  B05B15/50 ,  B65D47/18

Abstract: A dispenser has a body with a variable-volume storage chamber for storing substance, and a dispensing portion defining a dosage chamber in fluid communication with the storage chamber. A first valve includes a valve seat and a flexible valve cover seated thereon defining a normally-closed fluid-tight seam therebetween. The valve cover relative to moves from the valve seat to allow substance through the seam and out of the dispenser. A second valve allows substance from the storage chamber into the dosage chamber and substantially prevents flow from the dosage chamber into the storage chamber. An actuator is manually movable between (i) a first non-actuated position, and (ii) a second actuated position extending into the dosage chamber for compressing a dose of substance therein, dispensing substance through the first valve. The elasticity of the actuator causes it to return to the first non-actuated position upon manually releasing the actuator.

Abstract translation: 分配器具有主体，其具有用于存储物质的可变容积的储存室，以及限定与储存室流体连通的剂量室的分配部分。 第一阀包括阀座和位于其上的柔性阀盖，限定了它们之间的常闭流体密封接缝。 阀盖相对于从阀座移动以允许物质通过接缝并从分配器中排出。 第二阀允许物质从储存室进入剂量室，并且基本上防止从剂量室流入储存室。 致动器可以在（i）第一非致动位置和（ii）延伸到剂量室中的第二致动位置之间手动地移动，用于在其中压缩一定剂量的物质，通过第一阀分配物质。 当手动释放致动器时，致动器的弹性使其返回到第一非致动位置。

公开(公告)号：US20120042971A1

公开(公告)日：2012-02-23

申请号：US13213969

申请日：2011-08-19

Applicant: Daniel Py

Inventor： Daniel Py

IPC: F16L37/00 ,  B23P19/00

CPC classification number: F16L37/36 ,  A61M39/10 ,  A61M2039/1027 ,  F16L2201/44 ,  Y10T29/49826 ,  Y10T137/87925 ,  Y10T137/9029

Abstract: A connector for transferring a fluid includes a first connector and a second connector. Each connector includes a first outer portion including a first obstructive portion and defining a first fluid passageway for receiving a fluid therein. Each connector further includes a first central nozzle coupled to the first outer portion. The central nozzle includes a first engagement member. The first central nozzle is movable between a first position and a second position with rotation of the first outer portion. In the first position, the first obstructive portion and the first engagement portion substantially overlap to impede fluid flow through the first fluid passageway. In the second position, at least one of the first engagement member and the first obstructive member is displaced to allow fluid flow through the first fluid passageway.

Abstract translation: 用于传送流体的连接器包括第一连接器和第二连接器。 每个连接器包括第一外部部分，其包括第一阻塞部分并且限定用于在其中接收流体的第一流体通道。 每个连接器还包括联接到第一外部部分的第一中心喷嘴。 中心喷嘴包括第一接合构件。 第一中心喷嘴可以在第一外部部分旋转的同时在第一位置和第二位置之间移动。 在第一位置，第一阻塞部分和第一接合部分基本上重叠以阻止流体流过第一流体通道。 在第二位置，第一接合构件和第一阻塞构件中的至少一个被移位以允许流体流过第一流体通道。

公开(公告)号：USD650701S1

公开(公告)日：2011-12-20

申请号：US29367442

申请日：2010-08-09

Applicant: Daniel Py ,  Nathaniel Houle ,  Eric E. Hartman ,  Miles J. Flamenbaum

Designer： Daniel Py ,  Nathaniel Houle ,  Eric E. Hartman ,  Miles J. Flamenbaum

公开(公告)号：US20110253250A1

公开(公告)日：2011-10-20

申请号：US13169586

申请日：2011-06-27

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B3/04

CPC classification number: F26B5/06

Abstract: Device and method for lyophilizing a substance within the device and storing therein the lyophilized substance. The device defines a chamber for receiving therein the substance to be lyophilized, a penetrable and resealable portion of the device is penetrable or pierceable by a needle for filling the device with the substance, and a resulting hole therein is resealable by transmitting radiation from a radiation source thereon. A filter is connectable in fluid communication between an interior and exterior of the chamber for permitting fluid to flow therethrough in a direction from the interior to the exterior of the chamber, and for substantially preventing contaminants from flowing therethrough in a direction from the exterior to the interior of the chamber.

Abstract translation: 用于冻结装置内的物质并在其中储存冻干物质的装置和方法。 该装置限定用于在其中容纳待冷冻干燥的物质的腔室，该装置的可穿透和可重新密封的部分可被针穿透或穿刺，用于填充该物质的装置，并且其中产生的孔可通过从辐射辐射 来源。 过滤器可连接在室的内部和外部之间的流体连通中，以允许流体从腔室的内部到外部的方向流过其中，并且用于基本上防止污染物沿着从外部到外部的方向流过 室内

公开(公告)号：US20110240158A1

公开(公告)日：2011-10-06

申请号：US13080537

申请日：2011-04-05

Applicant: Daniel Py

Inventor： Daniel Py

IPC: E03B1/00 ,  B23P19/00

CPC classification number: F16L41/02 ,  A61M39/18 ,  A61M39/26 ,  A61M2039/267 ,  Y10T29/49826 ,  Y10T137/0318 ,  Y10T137/87925 ,  Y10T137/87949 ,  Y10T137/87957

Abstract: An aseptic fluid connector having a first connector including a first fluid passageway for receiving a fluid therein; a first port in fluid communication with the first fluid passageway for passage of the fluid therethrough; and a first deflecting member. The first deflecting member includes a first engaging portion radially spaced relative to the first port, and a first valve movable between a closed position and an open position with movement of the first engaging portion between a non-deflected position and a deflected position, respectively. In the non-deflected position, the first valve is located in the closed position forming a fluid-tight seal between the first valve and first port and preventing the passage of fluid therethrough, and in the deflected position, the first valve is located in the open position allowing the aseptic passage of fluid through the first port.

Abstract translation: 一种无菌流体连接器，其具有包括用于在其中接收流体的第一流体通道的第一连接器; 与第一流体通道流体连通以使流体通过其中的第一端口; 和第一偏转构件。 第一偏转构件包括相对于第一端口径向间隔开的第一接合部分，以及在关闭位置和打开位置之间可移动的第一阀，其中第一接合部分分别在非偏转位置和偏转位置之间移动。 在非偏转位置，第一阀位于关闭位置，在第一阀和第一端口之间形成流体密封并防止流体通过，并且在偏转位置，第一阀位于 打开位置允许流体通过第一端口的无菌通道。

公开(公告)号：USD644322S1

公开(公告)日：2011-08-30

申请号：US29379390

申请日：2010-11-18

Applicant: Daniel Py ,  Norbert M. Assion ,  Stephanie Ferreira

Designer： Daniel Py ,  Norbert M. Assion ,  Stephanie Ferreira

公开(公告)号：US08007193B2

公开(公告)日：2011-08-30

申请号：US12710516

申请日：2010-02-23

Applicant: Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

Inventor： Daniel Py ,  Julian Chan ,  David Fellows ,  Eric E. Hartman ,  Bing He

IPC: A46B11/02

CPC classification number: B65D83/0094 ,  A45D34/04 ,  A45D2200/055 ,  A45D2200/056 ,  A61M35/003 ,  B05B11/00416 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3033 ,  B05B11/3094 ,  B65B1/04 ,  B65D83/0033 ,  G01F11/025 ,  G01F11/08

Abstract: A dispenser for dispensing a substance, such as a pharmaceutical, ophthalmic, dermatological, cosmeceutical, cosmetic or other product, has a body with a variable-volume storage chamber for storing the product. A dispensing portion of the dispenser is connected with the body and has a compression chamber in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the compression chamber. A one-way valve of the dispenser includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser.

Abstract translation: 用于分配诸如药物，眼科，皮肤病学，药妆，化妆品或其他产品的物质的分配器具有用于存储产品的具有可变容积的储存室的主体。 分配器的分配部分与主体连接并且具有与储存室流体连通的用于从其接收物质的压缩室以及与压缩室流体连通的出口孔。 分配器的单向阀包括轴向延伸的阀座和位于阀座上的轴向延伸的柔性阀盖，并且在其间限定一个常闭的轴向延伸的接缝，形成在阀盖之间的流体密封 和阀座。 柔性阀盖可相对于阀座移动，并且接缝可与出口孔流体连通以允许物质通过接缝并从分配器中通过。

公开(公告)号：US07886937B2

公开(公告)日：2011-02-15

申请号：US12685359

申请日：2010-01-11

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65D88/54

CPC classification number: G01F11/021 ,  B05B11/3001 ,  B05B11/3015 ,  B05B11/3032 ,  B05B11/3047 ,  B05B11/3074 ,  B65D47/2031 ,  B65D83/00 ,  B65D83/0033 ,  B65D83/0072 ,  G01F11/02

Abstract: A dispenser has a housing, and a variable-volume storage chamber formed within the housing and defining a substantially fluid-tight seal between the chamber and exterior of the housing for storing a substance to be dispensed. A piston is mounted within the housing, and a one-way valve is mounted within the housing and coupled in fluid communication with the variable-volume storage chamber. A compression chamber is coupled in fluid communication between the piston and one-way valve, and at least one of the piston and valve is manually depressible relative to the other between (i) a first position in which the piston is located at least partially outside of the compression chamber for permitting substance to flow from the variable-volume storage chamber into the compression chamber, and (ii) a second position in which the piston is located at least partially within the compression chamber for pressurizing substance within the compression chamber above a valve opening pressure and, in turn, dispensing substance through the one-way valve and out of the dispenser.

Abstract translation: 分配器具有壳体和形成在壳体内的可变容积的储存室，并且在壳体的室和外部之间限定基本上流体密封的密封，用于存储待分配的物质。 活塞安装在壳体内，并且单向阀安装在壳体内并且与可变容积存储室流体连通地联接。 压缩室在活塞和单向阀之间流体连通地联接，并且活塞和阀门中的至少一个在第一位置之间相对于另一个手动地相对地被压下，其中活塞位于至少部分外部 的压缩室，用于允许物质从可变容积的储存室流入压缩室，以及（ii）第二位置，其中活塞至少部分地位于压缩室内，用于将压缩室内的物质加压在压缩室的上方 打开阀门的压力，并通过单向阀分配物质并从分配器中分出物质。

公开(公告)号：US07874129B2

公开(公告)日：2011-01-25

申请号：US12371601

申请日：2009-02-14

Applicant: Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

Inventor： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  M. Jeffrey Willey

IPC: B65B3/02 ,  B65B5/02

CPC classification number: B65B3/022

Abstract: Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

Abstract translation: 用于模制和填充具有本体的装置的装置，该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件，包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。 模具包括在无菌室内的多个模具腔，其形状形成封闭件和主体，以及基本上无菌的表面，其围绕并邻近模具腔的周边延伸。 包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分，其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。 柔性屏障耦合到模具和工具，以基本上防止污染物从模制机器和工具通过。

公开(公告)号：US20100331808A1

公开(公告)日：2010-12-30

申请号：US12874744

申请日：2010-09-02

Applicant: Daniel Py ,  Norbert M. Assion ,  Julian V. Chan

Inventor： Daniel Py ,  Norbert M. Assion ,  Julian V. Chan

IPC: A61M5/31 ,  G01F11/12 ,  B67D3/00

CPC classification number: B65D51/002 ,  A45D34/04 ,  A45D2200/055 ,  A61J1/1406 ,  A61J7/0053 ,  B05B11/02 ,  B67D99/00 ,  G01F11/027

Abstract: A dispenser is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials that may react upon exposure to air, such as glue. Means are provided in the dispenser to effect controlled delivery of a pre-determined amount of the substance contained in the dispenser. A one-way valve is provided to hermetically seal the portion of the dispenser containing the substance to be dispensed.

Abstract translation: 提供分配器用于向人或动物（例如药物，药物，化妆品和食品）递送受控量的计量量的任何不同物质，或者输送在暴露于空气中可能反应的材料，例如胶 。 在分配器中提供装置以实现预定量的包含在分配器中的物质的受控输送。 提供单向阀以气密地密封包含待分配物质的分配器的部分。