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    Multiple Dose Delivery Device with Manually Depressible Actuator and One-Way Valve for Storing and Dispensing Substances, and Related Method
    1.
    发明申请
    Multiple Dose Delivery Device with Manually Depressible Actuator and One-Way Valve for Storing and Dispensing Substances, and Related Method 审中-公开
    具有手动抑制致动器和存储和分配物质的单向阀的多剂量输送装置及相关方法

    公开(公告)号：US20130037574A1

    公开(公告)日：2013-02-14

    申请号：US13419352

    申请日：2012-03-13

    Applicant: Daniel Py ,  Beniot Adamo

    Inventor： Daniel Py ,  Beniot Adamo

    IPC: B65D37/00 ,  B65B3/04

    CPC classification number: B65D83/0033 ,  A61F9/0008 ,  B05B11/0027 ,  B05B11/007 ,  B05B11/0097 ,  B05B11/3032 ,  B05B15/50 ,  B65D47/18

    Abstract: A dispenser has a body with a variable-volume storage chamber for storing substance, and a dispensing portion defining a dosage chamber in fluid communication with the storage chamber. A first valve includes a valve seat and a flexible valve cover seated thereon defining a normally-closed fluid-tight seam therebetween. The valve cover relative to moves from the valve seat to allow substance through the seam and out of the dispenser. A second valve allows substance from the storage chamber into the dosage chamber and substantially prevents flow from the dosage chamber into the storage chamber. An actuator is manually movable between (i) a first non-actuated position, and (ii) a second actuated position extending into the dosage chamber for compressing a dose of substance therein, dispensing substance through the first valve. The elasticity of the actuator causes it to return to the first non-actuated position upon manually releasing the actuator.

    Abstract translation: 分配器具有主体，其具有用于存储物质的可变容积的储存室，以及限定与储存室流体连通的剂量室的分配部分。 第一阀包括阀座和位于其上的柔性阀盖，限定了它们之间的常闭流体密封接缝。 阀盖相对于从阀座移动以允许物质通过接缝并从分配器中排出。 第二阀允许物质从储存室进入剂量室，并且基本上防止从剂量室流入储存室。 致动器可以在（i）第一非致动位置和（ii）延伸到剂量室中的第二致动位置之间手动地移动，用于在其中压缩一定剂量的物质，通过第一阀分配物质。 当手动释放致动器时，致动器的弹性使其返回到第一非致动位置。

    Multiple dose delivery device with manually depressible actuator and one-way valve for storing and dispensing substances, and related method
    2.
    发明授权
    Multiple dose delivery device with manually depressible actuator and one-way valve for storing and dispensing substances, and related method 有权
    具有手动按压致动器和用于存储和分配物质的单向阀的多剂量输送装置及相关方法

    公开(公告)号：US08132695B2

    公开(公告)日：2012-03-13

    申请号：US11938144

    申请日：2007-11-09

    Applicant: Daniel Py ,  Beniot Adamo

    Inventor： Daniel Py ,  Beniot Adamo

    IPC: B65D37/00

    CPC classification number: B65D83/0033 ,  A61F9/0008 ,  B05B11/0027 ,  B05B11/007 ,  B05B11/0097 ,  B05B11/3032 ,  B05B15/50 ,  B65D47/18

    Abstract: A dispenser has a body with a variable-volume storage chamber for storing substance, and a dispensing portion defining a dosage chamber in fluid communication with the storage chamber. A first valve includes a valve seat and a flexible valve cover seated thereon defining a normally-closed fluid-tight seam therebetween. The valve cover relative to moves from the valve seat to allow substance through the seam and out of the dispenser. A second valve allows substance from the storage chamber into the dosage chamber and substantially prevents flow from the dosage chamber into the storage chamber. An actuator is manually movable between (i) a first non-actuated position, and (ii) a second actuated position extending into the dosage chamber for compressing a dose of substance therein, dispensing substance through the first valve. The elasticity of the actuator causes it to return to the first non-actuated position upon manually releasing the actuator.

    Abstract translation: 分配器具有主体，其具有用于存储物质的可变容积的储存室，以及限定与储存室流体连通的剂量室的分配部分。 第一阀包括阀座和位于其上的柔性阀盖，限定了它们之间的常闭流体密封接缝。 阀盖相对于从阀座移动以允许物质通过接缝并从分配器中排出。 第二阀允许物质从储存室进入剂量室，并且基本上防止从剂量室流入储存室。 致动器可以在（i）第一非致动位置和（ii）延伸到剂量室中的第二致动位置之间手动地移动，用于在其中压缩一定剂量的物质，通过第一阀分配物质。 当手动释放致动器时，致动器的弹性使其返回到第一非致动位置。

    Single use connectors
    3.
    发明授权
    Single use connectors 有权

    公开(公告)号：US10426701B2

    公开(公告)日：2019-10-01

    申请号：US15410762

    申请日：2017-01-19

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61J1/20 ,  A61M5/162 ,  A61M39/10 ,  A61M39/18 ,  A61M39/26

    Abstract: Connector assembly including a piercing member having a flow port therein attached to a first piece, with the piercing member slidingly receivable within a second piece, wherein the piercing member and the second pierce are movable relative to each other between a first position where the second pieces closes the flow port and a second position where the flow port is open. The first piece contains a locking mechanism that lockingly engages with a device when connected thereto, preventing subsequent disconnection of first piece and the device. Upon initial connection of the first piece to the device, the second piece is moved from the first position to the second position.

    Device with closure, one-way valve, and storage chamber and related method
    4.
    发明授权
    Device with closure, one-way valve, and storage chamber and related method 有权

    公开(公告)号：US09737435B2

    公开(公告)日：2017-08-22

    申请号：US13745721

    申请日：2013-01-18

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61F9/00 ,  B23P15/00 ,  B05B11/00 ,  B65D83/00

    CPC classification number: A61F9/0008 ,  B05B11/0056 ,  B05B11/0062 ,  B05B11/0067 ,  B05B11/007 ,  B05B11/0097 ,  B23P15/001 ,  B65D83/0022 ,  Y10T29/49412

    Abstract: A device has a first part with a valve seat and storage chamber, and a second part with a flexible valve cover and actuator. The storage chamber may be formed from a pre-form blow-molded into a flexible pouch defining a variable-volume storage chamber. The flexible valve cover and valve seat form a normally closed valve seam therebetween. The valve cover is movable in response to fluid at an inlet to the seam exceeding a valve opening pressure of the one-way valve between (i) a normally closed position with valve cover and valve seat in contact with each other and defining the normally closed seam, and (ii) a second position with at least a portion of the valve cover spaced away from the valve seat to allow the fluid to pass through the seam. The one-way valve may have anti-spritz features for using the device to dispense a substance, such as to the eye. The device may contain prostaglandins without the device material absorbing the prostaglandins material and/or without the material being adsorbed into the drug.

    Closure for a device with a base and a support
    7.
    发明授权
    Closure for a device with a base and a support 有权
    关闭设备与基地和支持

    公开(公告)号：US09211983B2

    公开(公告)日：2015-12-15

    申请号：US13847277

    申请日：2013-03-19

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65D35/56 ,  B65D47/24 ,  B65D23/02 ,  B65D47/32 ,  B05B11/00 ,  B29C47/00 ,  B29C47/06 ,  B29C49/04 ,  B29L9/00 ,  B29L31/00

    CPC classification number: B65D47/24 ,  B05B11/3028 ,  B29C47/0021 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/065 ,  B29C47/068 ,  B29C49/04 ,  B29L2009/00 ,  B29L2031/7158 ,  B65D23/02 ,  B65D47/205 ,  B65D47/32

    Abstract: A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.

    Abstract translation: 一种装置包括包含第一聚合物的第一部分和与第一部分相比具有相对柔性的第二部分，并且包括基本上不能与第一聚合物结合的第二聚合物。 该装置的腔室相对于环境气氛可气密地密封，并且由（i）第二部分的内部和/或（ii）形成在第一和第二部分之间的空间限定。 该装置的第三部分包括可与第一和第二聚合物结合的第三聚合物，并将第一和第二部分彼此固定地固定。

    ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE
    8.
    发明申请
    ONE-WAY VALVE AND APPARATUS AND METHOD OF USING THE VALVE 有权
    单向阀和装置以及使用阀的方法

    公开(公告)号：US20140246462A1

    公开(公告)日：2014-09-04

    申请号：US14101981

    申请日：2013-12-10

    Applicant: Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

    Inventor： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

    IPC: B65D37/00

    CPC classification number: B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

    Abstract: A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

    Abstract translation: 提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。 柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。 组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。 组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

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