公开(公告)号：US20220349009A1

公开(公告)日：2022-11-03

申请号：US17727128

申请日：2022-04-22

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Corporation

Inventor： William R. Taylor ,  Tracy C. Yab ,  Douglas W. Mahoney ,  John B. Kisiel ,  David A. Ahlquist ,  Hatim T. Allawi ,  Graham P. Lidgard ,  Maria Giakoumopoulos

IPC: C12Q1/6883 ,  C12Q1/6806

Abstract: Provided herein is technology for screening for esophageal disorders, including but not limited to, Barrett's esophagus (BE). In particular, provided herein are methods, compositions, and related uses for detecting the presence or absence of esophageal disorders from a biological sample.

公开(公告)号：US20210348239A1

公开(公告)日：2021-11-11

申请号：US17378267

申请日：2021-07-16

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Graham P. Lidgard ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

公开(公告)号：US20210262042A1

公开(公告)日：2021-08-26

申请号：US17314099

申请日：2021-05-07

Applicant: Exact Sciences Development Company, LLC ,  Mayo Foundation for Medical Education and Research

Inventor： Hatim Allawi ,  Graham P. Lidgard ,  Maria Giakoumopoulos ,  David A. Ahlquist ,  William R. Taylor ,  Douglas Mahoney

IPC: C12Q1/6886 ,  C12Q1/6806

Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.

公开(公告)号：US11078539B2

公开(公告)日：2021-08-03

申请号：US15301227

申请日：2015-03-26

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  Douglas W. Mahoney ,  Graham P. Lidgard ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

公开(公告)号：US11028447B2

公开(公告)日：2021-06-08

申请号：US16460647

申请日：2019-07-02

Applicant: Exact Sciences Development Company, LLC ,  Mayo Foundation for Medical Education and Research

Inventor： Hatim Allawi ,  Graham P. Lidgard ,  Maria Giakoumopoulos ,  David A. Ahlquist ,  William R. Taylor ,  Douglas Mahoney

IPC: C12Q1/6886 ,  C12Q1/6806

Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.

公开(公告)号：US20210130911A1

公开(公告)日：2021-05-06

申请号：US17144806

申请日：2021-01-08

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： David A. Ahlquist ,  William R. Taylor ,  John B. Kisiel ,  Tracy C. Yab ,  Douglas W. Mahoney ,  Brian A. Dukek ,  Matthew T. Gettman ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.

公开(公告)号：US20210130907A1

公开(公告)日：2021-05-06

申请号：US17085542

申请日：2020-10-30

Applicant: Mayo Foundation for Medical Education and Research ,  Exact Sciences Development Company, LLC

Inventor： William R. Taylor ,  John B. Kisiel ,  Douglas W. Mahoney ,  David A. Ahlquist ,  Hatim T. Allawi ,  Michael W. Kaiser

IPC: C12Q1/6886 ,  C12N15/117 ,  C12Q1/6869 ,  G01N33/50

Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).

公开(公告)号：US20200283853A1

公开(公告)日：2020-09-10

申请号：US15930267

申请日：2020-05-12

Applicant: Mayo Foundation for Medical Education and Research ,  EXACT SCIENCES DEVELOPMENT COMPANY, LLC

Inventor： David A. Ahlquist ,  John B. Kisiel ,  William R. Taylor ,  Tracy C. Yab ,  Douglas W. Mahoney ,  Graham P. Lidgard ,  Hatim T. Allawi

IPC: C12Q1/6886

Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.

公开(公告)号：US10590489B2

公开(公告)日：2020-03-17

申请号：US15724890

申请日：2017-10-04

Applicant: Mayo Foundation for Medical Education and Research

Inventor： William R. Taylor ,  Jonathan J. Harrington ,  Patrick S. Quint ,  Hongzhi Zou ,  Harold R. Bergen, III ,  David I. Smith ,  David A. Ahlquist

IPC: C12Q1/37 ,  C12Q1/6886 ,  C12Q1/40 ,  G01N33/574

Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.

公开(公告)号：US10385406B2

公开(公告)日：2019-08-20

申请号：US15471337

申请日：2017-03-28

Applicant: EXACT SCIENCES DEVELOPMENT COMPANY, LLC ,  Mayo Foundation for Medical Education and Research

Inventor： Hatim Allawi ,  Graham P. Lidgard ,  Maria Giakoumopoulos ,  David A. Ahlquist ,  William R. Taylor ,  Douglas Mahoney

IPC: C12Q1/6886 ,  C12Q1/6806 ,  A61K31/713

Abstract: Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.