公开(公告)号：US07158219B2

公开(公告)日：2007-01-02

申请号：US10942693

申请日：2004-09-16

Applicant: Zhiyong Li ,  Shih-Yuan Wang

Inventor： Zhiyong Li ,  Shih-Yuan Wang

IPC: G01N1/00 ,  G01J3/44

CPC classification number: G01N21/658 ,  B82Y30/00

Abstract: A SERS-active structure is disclosed that includes a substrate and at least one nanowire disposed on the substrate. The at least one nanowire includes a core including a first material and a coating including a SERS-active material. A SERS system is also disclosed that includes a SERS-active structure. Also disclosed are methods for forming a SERS-active structure and methods for performing SERS with SERS-active structures.

Abstract translation: 公开了一种SERS-活性结构，其包括衬底和设置在衬底上的至少一个纳米线。 所述至少一个纳米线包括包含第一材料和包含SERS-活性材料的涂层的芯。 还公开了包括SERS活性结构的SERS系统。 还公开了形成SERS活性结构的方法和用SERS活性结构进行SERS的方法。

公开(公告)号：US20060164635A1

公开(公告)日：2006-07-27

申请号：US11044421

申请日：2005-01-27

Applicant: M. Saif Islam ,  Shih-Yuan Wang ,  Wei Wu ,  Zhiyong Li ,  R. Stanley Williams

Inventor： M. Saif Islam ,  Shih-Yuan Wang ,  Wei Wu ,  Zhiyong Li ,  R. Stanley Williams

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658 ,  G01N2201/0873

Abstract: Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device for performing Raman spectroscopy comprises a substrate and a laser source disposed on the substrate. The laser source may be configured for emanating a laser radiation, which may irradiate an analyte disposed on a Raman enhancement structure. The Raman enhancement structure may be disposed in a waveguide. The molecular analysis device also includes a wavelength demultiplexer and radiation sensors disposed on the substrate and configured for receiving a Raman scattered radiation, which may be generated by the irradiation of the analyte and Raman enhancement structure.

公开(公告)号：US07050659B1

公开(公告)日：2006-05-23

申请号：US11096670

申请日：2005-03-31

Applicant: R. Stanley Williams ,  Raymond G. Beausoleil ,  Wei Wu ,  Zhiyong Li ,  Philip J. Kuekes

Inventor： R. Stanley Williams ,  Raymond G. Beausoleil ,  Wei Wu ,  Zhiyong Li ,  Philip J. Kuekes

IPC: G02F1/295

CPC classification number: G02F1/3511 ,  G02F1/0541 ,  G02F1/29 ,  G02F1/365 ,  G02F2202/13 ,  G02F2202/32

Abstract: Controlling the propagation of electromagnetic radiation is described. A photonic bandgap medium is placed in the path of the electromagnetic radiation, the photonic bandgap medium comprising a photorefractive material. Control radiation is projected onto a surface of the photonic bandgap medium. The control radiation spatially varies a refractive index of the photorefractive material to control propagation of the electromagnetic radiation through the photonic bandgap medium.

Abstract translation: 描述控制电磁辐射的传播。 光子带隙介质放置在电磁辐射的路径中，光子带隙介质包括光折射材料。 控制辐射投影到光子带隙介质的表面上。 控制辐射在空间上改变光折射材料的折射率，以控制通过光子带隙介质的电磁辐射的传播。

公开(公告)号：US20060077382A1

公开(公告)日：2006-04-13

申请号：US10964523

申请日：2004-10-13

Applicant: Shih-Yuan Wang ,  Zhiyong Li ,  M. Islam

Inventor： Shih-Yuan Wang ,  Zhiyong Li ,  M. Islam

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: Devices, systems, and methods using Surface Enhanced Raman Spectroscopy (SERS) are disclosed. A device for generating Raman scattered radiation comprises a laser source and a SERS-active structure. The laser source may be configured for emanating radiation from an emanating surface or by forming a depression in the laser source, which creates a region of increased evanescent field from the laser source. SERS systems and methods include a device for generating Raman scattered radiation with a detector configured to receive the Raman scattered radiation.

Abstract translation: 公开了使用表面增强拉曼光谱（SERS）的器件，系统和方法。 用于产生拉曼散射辐射的装置包括激光源和SERS-活性结构。 激光源可以被配置用于从发射表面发射辐射，或者通过在激光源中形成凹陷，其产生从激光源增加的渐逝场的区域。 SERS系统和方法包括用配置成接收拉曼散射辐射的检测器产生拉曼散射辐射的装置。

公开(公告)号：US20060055922A1

公开(公告)日：2006-03-16

申请号：US10942482

申请日：2004-09-16

Applicant: Zhiyong Li ,  Shih-Yuan Wang

Inventor： Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: SERS-active structures including features having nanoscale dimensions are disclosed, including methods for forming such SERS-active structures and methods for forming a plurality of such SERS-active structures. Methods for performing SERS using SERS-active structures also are disclosed.

Abstract translation: 公开了包括具有纳米级尺寸的特征的SERS活性结构，包括形成这种SERS-活性结构的方法和形成多个这样的SERS-活性结构的方法。 还公开了使用SERS活性结构来执行SERS的方法。

公开(公告)号：US09442071B2

公开(公告)日：2016-09-13

申请号：US14394287

申请日：2012-04-24

Applicant: Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

Inventor： Steven Barcelo ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Ansoon Kim

IPC: G01J3/44 ,  G01B11/16 ,  G01N21/00 ,  G01N33/566 ,  G01N30/96 ,  G01N21/65 ,  B82Y15/00

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01N2201/06113 ,  Y10S977/954

Abstract: An apparatus for performing a sensing application includes a reservoir to contain a solution, a dispenser to dispense the solution from the reservoir, and a substrate having a plurality of nano-fingers positioned to receive the dispensed solution, in which the plurality of nano-fingers are flexible, such that the plurality of nano-fingers are configurable with respect to each other. The apparatus also includes an illumination source to illuminate the received solution, an analyte introduced around the plurality of nano-fingers, and the plurality of nano-fingers, in which light is to be emitted from the analyte in response to being illuminated. The apparatus further includes a detector to detect the light emitted from the analyte.

Abstract translation: 用于执行感测应用的装置包括容纳溶液的储存器，用于从储存器分配溶液的分配器以及具有多个纳米手指的基板，该多个纳米手指定位成接收分配的溶液，其中多个纳米手指 是柔性的，使得多个纳米手指可相对于彼此配置。 所述装置还包括照亮所接收的溶液的照明源，围绕所述多个纳米手指引入的分析物和所述多个纳米手指，其中光将响应于被照亮从分析物发射。 该装置还包括检测器，用于检测从分析物发射的光。

公开(公告)号：US09176467B2

公开(公告)日：2015-11-03

申请号：US13548981

申请日：2012-07-13

Applicant: Weidong Gu ,  Geming Ding ,  Yonghong Li ,  Zhiyong Li ,  Jianxin Cao ,  Xiong Li ,  Xiaobing Liu

Inventor： Weidong Gu ,  Geming Ding ,  Yonghong Li ,  Zhiyong Li ,  Jianxin Cao ,  Xiong Li ,  Xiaobing Liu

IPC: G03G21/00 ,  G03G21/18

CPC classification number: G03G21/1857 ,  G03G21/186

Abstract: The invention relates to a process cartridge, which comprises a process cartridge housing, a photosensitive member, a driving force receiving opening, a retractable mechanism and a control mechanism, wherein the photosensitive member is arranged inside the process cartridge housing; the driving force receiving opening is connected with the photosensitive member and provides a driving force for the photosensitive member; the retractable mechanism allows the driving force receiving opening to extend or retract in the axial direction of the photosensitive member; and the control mechanism controls the extension and retraction of the retractable mechanism.

Abstract translation: 本发明涉及一种处理盒，其包括处理盒壳体，感光构件，驱动力接收开口，可伸缩机构和控制机构，其中感光构件布置在处理盒壳体内; 驱动力接收开口与感光构件连接，并为感光构件提供驱动力; 可伸缩机构允许驱动力接收开口在感光构件的轴向方向上延伸或缩回; 并且控制机构控制伸缩机构的伸缩。

公开(公告)号：US09084807B2

公开(公告)日：2015-07-21

申请号：US13816105

申请日：2011-08-04

Applicant: Chunshan Tang ,  Ning Xie ,  Xiaoling Yang ,  Wuqing Lv ,  Zhiyong Li ,  Jingying Ye ,  Difa Liu ,  Fan Cheng

Inventor： Chunshan Tang ,  Ning Xie ,  Xiaoling Yang ,  Wuqing Lv ,  Zhiyong Li ,  Jingying Ye ,  Difa Liu ,  Fan Cheng

IPC: A61K31/7048 ,  A61K9/00 ,  A61K31/352 ,  A61K45/06 ,  A61K47/18 ,  A61K36/185

CPC classification number: A61K31/7048 ,  A61K9/00 ,  A61K9/0095 ,  A61K31/352 ,  A61K36/185 ,  A61K45/06 ,  A61K47/18 ,  A61K2236/30 ,  A61K2300/00

Abstract: Disclosed is a composition comprising ligustroflavone, rhoifolin and hyperin, which is prepared according to rational weight ratio: 40% to 80% ligustroflavone, 5% to 45% rhoifolin and 1% to 40% hyperin. The composition can be used as a neuraminidase inhibitor for preventing and treating influenza, and can be formulated into pharmaceutically acceptable dosage forms.

Abstract translation: 公开了一种组合物，其包含根据合理的重量比：40％至80％的连翘黄酮，5％至45％的罗霍林和1％至40％的高辛酸制备的顺黄酮，罗霍林和羟乙酸。 该组合物可以用作预防和治疗流感的神经氨酸酶抑制剂，并且可以配制成药学上可接受的剂型。

公开(公告)号：US09080980B2

公开(公告)日：2015-07-14

申请号：US14233957

申请日：2011-07-27

Applicant: Alexandre M Bratkovski ,  Zhiyong Li

Inventor： Alexandre M Bratkovski ,  Zhiyong Li

IPC: G01J3/44 ,  G01N21/65 ,  G01N21/01

CPC classification number: G01N21/658 ,  G01N21/01

Abstract: A surface enhanced Raman spectroscopy (SERS) apparatus employs a nanorod in an indentation in a surface of a substrate. The SERS apparatus includes the nanorod having a tip at a free end opposite to an end of the nanorod that is supported by the substrate indentation. The indentation has a tapered profile and supports the nanorod at a bottom of the indentation. The free end of the nanorod extends away from the indentation bottom. The SERS apparatus further includes a Raman-active material at a surface of one or both of the nanorod and the indentation. The indentation and the nanorod facilitate one or both of production and detection of a Raman scattering signal emitted by an analyte in a vicinity of the nanorod and indentation.

Abstract translation: 表面增强拉曼光谱（SERS）装置在衬底的表面中采用在压痕中的纳米棒。 SERS装置包括在由衬底压痕支撑的纳米棒的端部相对的自由端处具有尖端的纳米棒。 压痕具有锥形轮廓并且支撑在压痕底部的纳米棒。 纳米棒的自由端延伸远离压痕底部。 SERS装置还包括在纳米棒和凹陷中的一个或两个的表面处的拉曼活性材料。 压痕和纳米棒促进由纳米棒和压痕附近的分析物发射的拉曼散射信号的生成和检测中的一个或两个。

公开(公告)号：US20150103340A1

公开(公告)日：2015-04-16

申请号：US14405334

申请日：2012-07-29

Applicant: Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Shih-Yuan Wang ,  Huei Pei Kuo ,  Steven Barcelo ,  Zhang-Lin Zhou

Inventor： Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Shih-Yuan Wang ,  Huei Pei Kuo ,  Steven Barcelo ,  Zhang-Lin Zhou

IPC: G01N21/65

CPC classification number: G01N21/658 ,  B82Y15/00 ,  G01J3/4412 ,  G01N2021/651 ,  G01N2201/06113 ,  Y10S977/902

Abstract: A scattering spectroscopy nanosensor includes a nanoscale-patterned sensing substrate to produce an optical scattering response signal indicative of a presence of an analyte when interrogated by an optical stimulus. The scattering spectroscopy nanosensor further includes a protective covering to cover and protect the nanoscale-patterned sensing substrate. The protective covering is to be selectably removed by exposure to an optical beam incident on the protective covering. The protective covering is to prevent the analyte from interacting with the nanoscale-patterned sensing substrate prior to being removed.

Abstract translation: 散射光谱纳米传感器包括纳米级图案化的感测衬底，以产生指示当通过光学刺激询问的分析物存在时的光学散射响应信号。 散射光谱纳米传感器还包括覆盖并保护纳米级图案化感测基板的保护覆盖层。 通过暴露在入射到保护罩上的光束可选地去除保护罩。 保护性覆盖物是在去除之前防止分析物与纳米级图案化的感测基板相互作用。