公开(公告)号：US20140091798A1

公开(公告)日：2014-04-03

申请号：US14123186

申请日：2012-02-23

申请人： MEGAFINE PHARMA (P) LTD.

发明人： Arjun Arunachalam

IPC分类号： G01R33/54

CPC分类号： G01R33/54 ,  G01R33/4824 ,  G01R33/4833 ,  G01R33/4836 ,  G01R33/5611 ,  G01R33/56308

摘要： A system and method for rapid acquisition of MRI data at multiple points in time in an. MRI scan using tailored excitation modules, said method comprising the steps of: obtaining tailored signal excitation modules by using RF excitation pulses in combination with one or more magnetic field gradients; acquiring an aliased k-space dataset at a point in time using a pulse sequence that employs said obtained tailored signal excitation modules, which tag and overlap distinct k-space points; repeating steps (a) and (b) for acquiring aliased k-space datasets at multiple time points in a scan while tagging the overlapped, k-space points as a function of time to obtain an accelerated k-t dataset; undoing k-space aliasing m the acquired k-space datasets by Fourier transforming them along the time axis followed by a filtering process to separate the overlapped points; and performing a Fourier transformation along one or more axes, of the un-aliased k-space datasets to generate image frames for the different time points at which data was acquired.

摘要翻译： 一种用于在多个时间点快速获取MRI数据的系统和方法。 所述方法包括以下步骤：通过使用RF激励脉冲与一个或多个磁场梯度组合来获得定制的信号激励模块; 使用采用所获得的定制信号激励模块的脉冲序列在某个时间点获取混叠的k空间数据集，该标记和重叠不同的k空间点; 重复步骤（a）和（b），用于在扫描中的多个时间点获取混叠的k空间数据集，同时标记重叠的k空间点作为时间的函数，以获得加速的k-t数据集; 通过对所获取的k空间数据集进行k空间混叠，沿着时间轴对其进行傅立叶变换，然后进行滤波处理以分离重叠点; 以及沿着所述未锯齿的k空间数据集的一个或多个轴执行傅里叶变换，以生成用于获取数据的不同时间点的图像帧。

公开(公告)号：US20130293231A1

公开(公告)日：2013-11-07

申请号：US13978930

申请日：2012-01-11

申请人： Kosuke Hirai

发明人： Kosuke Hirai

IPC分类号： G01R33/48

CPC分类号： G01R33/4828 ,  A61B5/055 ,  G01R33/4836 ,  G01R33/5602 ,  G01R33/5613 ,  G01R33/5635

摘要： In order to acquire an image with enhanced contrast between a fluid portion and a stationary portion without extending the aging time even when an IR pulse is used as an RF pre-pulse, the RF pre-pulse is applied to a region upstream of an imaging region so as to excite longitudinal magnetization of the fluid portion in a negative direction, an echo signal is measured from the imaging region, and an image with enhanced contrast of the fluid portion with respect to the stationary portion is acquired on the basis of phase information of an image reconstructed by using the echo signal.

摘要翻译： 为了获得具有增强的流体部分和静止部分之间的对比度的图像，即使当使用IR脉冲作为RF预脉冲时，也不延长老化时间，RF预脉冲被施加到成像的上游区域 区域，以便沿着负方向激发流体部分的纵向磁化，从成像区域测量回波信号，并且基于相位信息获取流体部分相对于静止部分的对比度增强的图像 通过使用回波信号重建的图像。

公开(公告)号：US20130249549A1

公开(公告)日：2013-09-26

申请号：US13847680

申请日：2013-03-20

申请人： Josef Pfeuffer ,  Rainer Schneider

发明人： Josef Pfeuffer ,  Rainer Schneider

IPC分类号： G01R33/54 ,  G01R33/28

CPC分类号： G01R33/543 ,  G01R33/28 ,  G01R33/4833 ,  G01R33/4836 ,  G01R33/5612

摘要： In method and a control sequence determination device to determine a magnetic resonance system control sequence that includes at least one radio-frequency pulse train to be emitted by a magnetic resonance system, a target magnetization (m) is initially detected, and an energy distribution function in k-space is determined on the basis of the target magnetization. A k-space trajectory is then determined under consideration of the energy distribution function in k-space, for which the radio-frequency pulse train is then determined in an RF pulse optimization method. The method is suitable for operation of a magnetic resonance system, and a magnetic resonance system includes such a control sequence determination device.

摘要翻译： 在方法和控制序列确定装置中，确定包括由磁共振系统发射的至少一个射频脉冲串的磁共振系统控制序列，最初检测目标磁化（m），并且能量分布函数 基于目标磁化确定k空间。 然后考虑k空间中的能量分布函数来确定k空间轨迹，然后在RF脉冲优化方法中确定射频脉冲序列。 该方法适用于磁共振系统的操作，并且磁共振系统包括这样的控制顺序确定装置。

公开(公告)号：US20120212223A1

公开(公告)日：2012-08-23

申请号：US13504590

申请日：2010-11-11

申请人： Takashi Nishihara ,  Hiroyuki Itagaki

发明人： Takashi Nishihara ,  Hiroyuki Itagaki

IPC分类号： G01R33/48

CPC分类号： G01R33/4828 ,  A61B5/055 ,  A61B5/4312 ,  A61B5/7257 ,  G01R33/4836

摘要： An MRI apparatus and a two-dimensional excitation adjustment method capable of performing appropriately two-dimensional excitation of a region, in which materials with different resonance frequencies are present, according to imaging conditions are provided. In order to do so, when performing the two-dimensional excitation of a two-dimensional excitation region of an object formed by a first material with a first resonance frequency and a second material with a second resonance frequency, an irradiation frequency of a high-frequency magnetic field for the two-dimensional excitation is set on the basis of the imaging conditions related to the two-dimensional excitation and the first and second resonance frequencies so that desired regions of the first and second materials are excited in a two-dimensional manner.

摘要翻译： 提供了能够根据成像条件对存在不同谐振频率的材料进行适当二维激励的MRI装置和二维激励调整方法。 为了这样做，当由具有第一共振频率的第一材料形成的物体的二维激发区域和具有第二共振频率的第二材料进行二维激发区域的二维激发时， 基于与二维激励和第一和第二共振频率相关的成像条件来设定用于二维激励的高频磁场，使得第一和第二材料的期望区域以二维方式被激发 。

公开(公告)号：US08237439B2

公开(公告)日：2012-08-07

申请号：US12540411

申请日：2009-08-13

申请人： Seung-Kyun Lee

发明人： Seung-Kyun Lee

IPC分类号： G01V3/00

CPC分类号： G01R33/4836 ,  G01R33/4833

摘要： A magnetic resonance imaging apparatus having a static magnetic field source, a plurality of radio frequency magnetic field sources and a plurality of gradient magnetic field sources for generating a gradient magnetic field is provided. The static magnetic field source generates a static magnetic field for aligning a spin vector of an object in a direction of the magnetic field and plurality of radio frequency magnetic field sources generate a radio frequency magnetic field for rotating the spin vector by an angle. The apparatus further includes a processor for generating a plurality of radio frequency excitation pulses for the plurality of radio frequency magnetic field sources and a plurality of gradient excitation pulses for the plurality of gradient magnetic field sources. The second half of each of the plurality of radio frequency excitation pulses comprises a time-reversed first half of a respective one of the plurality of radio frequency excitation pulses and the second half of each of the plurality of gradient excitation comprises a time-reversed and sign-reversed first half of a respective one of the plurality of gradient excitation pulses. The average value of each of the plurality of gradient excitation pulses is zero.

摘要翻译： 提供一种具有静态磁场源，多个射频磁场源和用于产生梯度磁场的多个梯度磁场源的磁共振成像装置。 静磁场源产生用于使物体在磁场方向上的自旋向量对准的静磁场，并且多个射频磁场源产生用于使旋转矢量旋转角度的射频磁场。 该装置还包括用于产生多个射频磁场源的多个射频激励脉冲和多个梯度磁场源的多个梯度激励脉冲的处理器。 多个射频激励脉冲中的每一个的后半部分包括多个射频激励脉冲中的相应一个的时间反转的前半部分，并且多个梯度激励中的每一个的后半部分包括时间反转和 符号反转多个梯度激励脉冲中的相应一个梯形激励脉冲的前半部分。 多个梯度激励脉冲的平均值为零。

公开(公告)号：US20120176132A1

公开(公告)日：2012-07-12

申请号：US13496916

申请日：2010-09-16

申请人： Takashi Nishihara ,  Hiroyuki Itagaki ,  Tomohiro Goto

发明人： Takashi Nishihara ,  Hiroyuki Itagaki ,  Tomohiro Goto

IPC分类号： G01R33/48

CPC分类号： A61B5/055 ,  A61B5/489 ,  G01R33/243 ,  G01R33/3875 ,  G01R33/446 ,  G01R33/4836

摘要： A high-quality image is obtained using a two-dimensional selective excitation method even if the static magnetic field is not uniform. Therefore, non-uniformity of a static magnetic field of a region to be focused in particular in a selective excitation region excited by 2DRF is measured, and a result of the measurement is reflected in an imaging sequence using the 2DRF. For example, a resonance frequency of magnetization obtained from the measurement result is set as an irradiation frequency of the 2DRF. In addition, a shim gradient magnetic field is applied so as to correct the non-uniformity of the magnetization obtained from the measurement result. These are applied only in the imaging sequence using the 2DRF, and an irradiation frequency and a shim gradient magnetic field set in a conventional method are used in other imaging sequences.

摘要翻译： 即使静态磁场不均匀，也可以使用二维选择激励法获得高质量的图像。 因此，特别是要被2DRF激发的选择性激发区域中的区域的静态磁场的不均匀性被测量，并且测量结果被反映在使用2DRF的成像序列中。 例如，将从测定结果得到的磁化的共振频率设定为2DRF的照射频率。 此外，施加垫片梯度磁场，以校正从测量结果获得的磁化的不均匀性。 这些仅在使用2DRF的成像序列中应用，并且在其他成像序列中使用常规方法中设置的照射频率和匀场梯度磁场。

公开(公告)号：US20120025825A1

公开(公告)日：2012-02-02

申请号：US13196135

申请日：2011-08-02

申请人： David Andrew Porter

发明人： David Andrew Porter

IPC分类号： G01R33/48 ,  G01R33/36

CPC分类号： G01R33/5617 ,  G01R33/4836 ,  G01R33/56341 ,  G01R33/565

摘要： In a method and magnetic resonance (MR) apparatus to acquire spin echo-based MR signals of an examination subject with a multi-spin echo sequence with multiple refocusing pulses after a single excitation pulse in an MR system that has a multichannel RF transmission and reception module: detect a spatial, two-dimensional phase distribution in the examination subject is detected by acquiring navigator signals, a phase and amplitude distribution for the individual transmission channels of the RF transmission and reception module is calculated to generate a magnetic field B1 for one of the RF refocusing pulses to generate the spin echo-based MR signal under consideration of the spatial phase distribution of the navigator signals, and this RF refocusing pulse is radiated via the multichannel RF transmission and reception module with the calculated phase and amplitude distributions of the individual transmission channels.

摘要翻译： 在具有多通道RF发射和接收的MR系统中的单个激励脉冲之后，利用具有多个重聚焦脉冲的多自旋回波序列获取检查对象的基于自旋回波的MR信号的方法和磁共振（MR）装置中 模块：通过获取导航信号检测检查对象中的空间二维相位分布，计算RF发送和接收模块的各个传输信道的相位和幅度分布，以产生一个磁场B1 RF再聚焦脉冲，以在考虑导航信号的空间相位分布的情况下产生基于自旋回波的MR信号，并且该RF重聚焦脉冲经由多通道RF发射和接收模块以所计算的个体的相位和幅度分布被辐射 传输通道。

公开(公告)号：US08085046B2

公开(公告)日：2011-12-27

申请号：US12550074

申请日：2009-08-28

申请人： Adam C Zelinski ,  Lawrence L Wald ,  Elfar Adalsteinsson ,  Vivek K Goyal ,  Vijay Alagappan

发明人： Adam C Zelinski ,  Lawrence L Wald ,  Elfar Adalsteinsson ,  Vivek K Goyal ,  Vijay Alagappan

IPC分类号： G01V3/00

CPC分类号： G01R33/5611 ,  G01R33/3664 ,  G01R33/4833 ,  G01R33/4836 ,  G01R33/5612

摘要： A method for target-dependent, sparsity-enforced selection for choosing a substantially optimal connection of radiofrequency (“RF”) transmitters to the elements of the RF coil array is provided. In particular, a method is provided that selects the linear combinations of the “N” spatial mode profiles of a transmission RF coil array, such that the k-space trajectory and pulse duration acceleration capabilities of the array are advantageously utilized. A sparsity-enforcement method that determines a subset of the available spatial modes for a parallel transmission RF coil array is employed to this end. In this manner, the utilization of the encoding power of a highly-parallel N-mode coil array in a system with only “P” available excitation channels is enabled.

摘要翻译： 提供了用于选择用于选择射频（RF））发射机到RF线圈阵列的元件的基本上最佳连接的目标依赖，稀疏执行选择的方法。 具体地，提供了一种选择发射RF线圈阵列的“N”个空间模式分布的线性组合的方法，使得有利地利用阵列的k空间轨迹和脉冲持续时间加速能力。 为此，采用了稀疏执行方法来确定并行传输RF线圈阵列的可用空间模式的子集。 以这种方式，能够在仅具有“P”可用激励信道的系统中利用高并行N模式线圈阵列的编码功率。

公开(公告)号：US20110267052A1

公开(公告)日：2011-11-03

申请号：US13141089

申请日：2009-11-23

申请人： Thomas S. Cull ,  William McLemore

发明人： Thomas S. Cull ,  William McLemore

IPC分类号： G01R33/44

CPC分类号： G01R33/4608 ,  G01N24/088 ,  G01R33/3614 ,  G01R33/4633 ,  G01R33/4836

摘要： A magnetic resonance apparatus (10) includes a magnet (18) that generates a static magnetic field, e.g., 7T, a resonance excitation system (26, 30, 32) induces resonance in an observed nuclear species such as 13C or 31P. A decoupling delay generator (48) introduces pauses between adjacent pulses of a decoupling pulse train configured to decouple a coupled species such as 1H. An RF amplifier (32, 44) whose energy shortage capacity would be exceeded by the pulse train without the pauses amplifies the pulse train with the pauses. The pauses are sufficiently short that decoupling and Nuclear Overhauser Effect enhancement are not adversely affected, but long enough to provide recovery time to the RF amplifier, e.g., 0.2 msec.

摘要翻译： 磁共振装置（10）包括产生静态磁场（例如7T）的磁体（18），共振激发系统（26,30,32）在观察到的核物质如13C或31P中引起共振。 解耦延迟发生器（48）引入解耦脉冲串的相邻脉冲之间的暂停，其被配置为使耦合的物质例如1H去耦。 一个RF放大器（32,44），其能量短缺容量将被脉冲串超过，而不会暂停，脉冲串将随着暂停放大。 暂停时间足够短，使得去耦和核超越效应增强不会受到不利影响，但长度足以为RF放大器提供恢复时间，例如0.2毫秒。

公开(公告)号：US07915892B2

公开(公告)日：2011-03-29

申请号：US12112499

申请日：2008-04-30

申请人： Kazuya Okamoto

发明人： Kazuya Okamoto

IPC分类号： G01V3/00

CPC分类号： G01R33/34046 ,  G01R33/3415 ,  G01R33/3664 ,  G01R33/4833 ,  G01R33/4836 ,  G01R33/5612

摘要： A magnetic resonance imaging apparatus that applies a gradient magnetic field and a radio-frequency magnetic field to a subject in a static magnetic field to image the subject based on magnetic resonance signals emitted from the subject, includes a unit which generates K transmission radio-frequency pulse signals required to produce the radio-frequency magnetic field, an allocation unit which allocates the K transmission radio-frequency pulse signals to K in M transmission signal paths, a connection unit to which at most M radio-frequency coils are attachable and which selectively connects the M transmission signal paths and M reception signal paths to the radio-frequency coils, a selection unit which selects N in magnetic resonance signals which are respectively received by the at most M radio-frequency coils and transmitted through the at most M reception signal paths, and a unit which performs reception processing for each of the selected N magnetic resonance signals.

摘要翻译： 一种磁共振成像装置，其将基于从被检体发出的磁共振信号对静态磁场施加梯度磁场和射频磁场，对被摄体进行成像，包括：生成K个发射频率的单位 产生射频磁场所需的脉冲信号，在M个发送信号路径中将K个发送射频脉冲信号分配给K的分配单元，至多可连接M个射频线圈的连接单元， 将M个发送信号路径和M个接收信号路径连接到射频线圈;选择单元，其选择分别由最多M个射频线圈接收并通过最多M个接收信号发送的磁共振信号中的N个 路径，以及对所选择的N个磁共振信号进行接收处理的单元。