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    Sterile filling machine having needle filling station within e-beam chamber
    121.
    发明申请
    Sterile filling machine having needle filling station within e-beam chamber 有权
    无菌灌装机在电子束室内具有针加注站

    公开(公告)号：US20070079896A1

    公开(公告)日：2007-04-12

    申请号：US11527775

    申请日：2006-09-25

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65B1/04

    CPC classification number: B65B3/04 ,  A61L2/08 ,  A61L2/087 ,  A61L2/24 ,  A61L2202/14 ,  B65B3/003 ,  B65B7/16 ,  B65B7/161 ,  B65B55/025 ,  B65B55/08 ,  B65B55/16

    Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a heat resealable stopper and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the stopper and chamber for sterilizing the container. The previously sterilized containers are then transported through an e-beam chamber, wherein an electron beam is directed onto a penetrable surface of the stopper to sterilize the penetrable surface. A needle is mounted within the e-beam chamber and moved into engagement with the stopper to pierce the sterilized penetrable surface of the stopper and inject the substance through the needle and into the chamber of the container. The needle is then withdrawn from the stopper and the filled container is transported outside of the e-beam chamber. Laser energy is then transmitted onto the penetrated surface of the stopper to fuse the stopper material and hermetically re-seal the stopper.

    Abstract translation: 提供了一种无菌灌装机及相关方法，用于无菌填充具有物质的容器。 容器包括可热再封塞的塞子和用于在其中容纳物质的腔室。 密封的空容器经受能够穿过塞子和室的辐射，以对容器进行灭菌。 先前灭菌的容器然后通过电子束室传送，其中电子束被引导到塞子的可穿透表面上以对可穿透表面进行消毒。 针安装在电子束室内并与止动器接合，以刺穿塞子的消毒的可渗透表面并将物质通过针头注入容器的腔室。 然后将针从止动器中取出，并将填充的容器运送到电子束室外部。 然后将激光能量传递到塞子的穿透表面上，以使塞子材料熔化并密封地重新密封塞子。

    Container and valve assembly for storing and dispensing substances, and related method
    123.
    发明申请
    Container and valve assembly for storing and dispensing substances, and related method 有权

    公开(公告)号：US20060131340A1

    公开(公告)日：2006-06-22

    申请号：US11301659

    申请日：2005-12-12

    Applicant: Daniel Py ,  Julian Chan

    Inventor： Daniel Py ,  Julian Chan

    IPC: B65D37/00

    CPC classification number: B65D35/46 ,  B65D47/205 ,  B65D47/2056 ,  B65D47/2081

    Abstract: A container and valve assembly for storing and dispensing substances including edible substances. The container is a tubular body that defines a storage chamber for storing the substance and a head portion for supports the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seem between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.

    Dispenser and apparatus and method for filling a dispenser
    128.
    发明授权
    Dispenser and apparatus and method for filling a dispenser 有权

    公开(公告)号：US06997219B2

    公开(公告)日：2006-02-14

    申请号：US10843902

    申请日：2004-05-12

    Applicant: Daniel Py ,  Julian V. Chan

    Inventor： Daniel Py ,  Julian V. Chan

    IPC: B65B1/04

    CPC classification number: B65D83/62 ,  A61J1/00 ,  A61J1/1443 ,  B65B3/30 ,  B65B31/044 ,  B65D83/425

    Abstract: A dispenser for holding multiple doses of fluids or other substances, and for dispensing the substances, has a vial, a flexible bladder received within the vial, and a variable volume storage chamber formed between the bladder and vial. A filling valve is coupled in fluid communication with the storage chamber and defines (1) a normally closed, fluid-tight position hermetically sealing the storage chamber from the ambient atmosphere, and (2) an open position allowing the passage of fluid through the valve both to evacuate the storage chamber and to introduce fluid through the valve to fill the storage chamber. A pump is coupled in fluid communication with the storage chamber for pumping fluids out of the storage chamber. A dispensing valve is coupled in fluid communication with the pump and defines (1) a normally closed, fluid-tight position preventing the passage of fluid out of the dispenser, and (2) an open position for dispensing pumped fluid therethrough. The sealed, empty dispenser is sterilized, such as by applying gamma radiation thereto. Then, the sterilized, sealed, empty dispenser is filled with fluid by engaging the filling valve with an evacuating/dispensing member to evacuate the storage chamber, and by introducing fluid from the filling member through the open filling valve and into the storage chamber. The filling member is withdrawn from the valve, and a spring moves the valve to a closed position to hermetically seal the fluid within the dispenser.

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