公开(公告)号：US12083254B2

公开(公告)日：2024-09-10

申请号：US17483816

申请日：2021-09-24

申请人： JGC JAPAN CORPORATION

发明人： Takeshi Kobayashi ,  Takeshi Kojima

IPC分类号： A61L2/26 ,  A61L2/08 ,  A61L9/14 ,  B01D53/86 ,  B01D53/88

CPC分类号： A61L9/14 ,  A61L2/082 ,  A61L2/087 ,  A61L2/26 ,  B01D53/8675 ,  B01D53/885 ,  A61L2202/11 ,  A61L2202/122 ,  A61L2202/13 ,  A61L2202/23 ,  B01D2257/106

摘要： A shielding structure of an object sterilized by radiation. The object is a housing that accommodates an accommodated object therein and is formed of a shielding material that shields the radiation and secondary radiation that has a higher transparency than the radiation and is secondarily generated by the radiation, an exterior of the housing is sterilized by the radiation, and the radiation and the secondary radiation do not penetrate through the accommodated object.

公开(公告)号：US12070742B2

公开(公告)日：2024-08-27

申请号：US16646602

申请日：2018-09-14

申请人： VETTER PHARMA-FERTIGUNG GMBH & CO. KG

发明人： Stefan Mossig

IPC分类号： B01L1/04 ,  A61L2/07 ,  A61L2/08 ,  B01L9/06 ,  B08B15/02 ,  B25J19/00 ,  B25J21/00 ,  F24F3/167

CPC分类号： B01L1/04 ,  A61L2/07 ,  A61L2/087 ,  B01L9/06 ,  B08B15/026 ,  B25J19/0075 ,  B25J21/005 ,  F24F3/167 ,  A61L2202/181 ,  B01L2300/123

摘要： The invention relates to a portable clean room for filling at least one medicine container, located in the clean room with at least one active substance, wherein: the clean room is enclosed in an airtight manner by an at least partially flexible shell, the shell has at least one active substance connection region which can be opened, and a manipulation device and at least one medicine container are located in the clean room. According to the invention, the shell has at least one actuation connection region, wherein the manipulation device has at least one filling device which can be coupled to the active substance connection region for introducing at least one active substance into the at least one medicine container arranged in the clean room, and the manipulation device can be actuated by means of an actuation device via the actuation connection region of the shell, and is designed to displace the filling device—relative to the at least one medicine container—and/or to actuate the filling device.

公开(公告)号：US20240261452A1

公开(公告)日：2024-08-08

申请号：US18557149

申请日：2023-01-18

申请人： AIREX CO., LTD.

发明人： Koji KAWASAKI ,  Daisuke KAKUDA ,  Yoshitaka OGATA ,  Jun MASUDOME ,  Haruka FUTAMURA ,  Tsukasa KITANO ,  Zhiqiang GUO

IPC分类号： A61L2/26 ,  A61L2/08 ,  A61L2/22 ,  B65B51/20 ,  B65B55/02 ,  B65B55/08 ,  B65B55/24 ,  B65D65/38 ,  B65D77/20

CPC分类号： A61L2/26 ,  A61L2/087 ,  A61L2/22 ,  B65B51/20 ,  B65B55/027 ,  B65B55/08 ,  B65B55/24 ,  B65D65/38 ,  B65D77/2024 ,  A61L2202/11 ,  A61L2202/122 ,  A61L2202/123 ,  A61L2202/13 ,  A61L2202/15 ,  A61L2202/182 ,  A61L2202/23 ,  B65D2565/388

摘要： A continuous decontamination-and-sterilization device possessing high efficiency, reliability, and safety of operation to treat external surfaces of a package that is conveyed to a sterile working chamber. A decontamination chamber decontaminates (with a decontamination agent) bottom and lateral external surfaces of the package conveyed by a first conveyance, with an upper surface seal portion of the package being sealed. An aeration chamber removes residue of decontamination agent from an external surface of the package while the package is conveyed by a second conveyance means. A sterilization chamber sterilizes the upper surface seal portion of the package by irradiating electron beams as the package is conveyed by a third conveyance means, with the bottom or lateral external surface of the package being supported. The first conveyance means includes a sealing means by an adsorbing function to adsorb and capture the upper surface seal portion so as to seal the same and convey the package, with the bottom and lateral external surface portions of the package being open.

公开(公告)号：US20240066159A1

公开(公告)日：2024-02-29

申请号：US18503086

申请日：2023-11-06

申请人： GRIFOLS ENGINEERING, S.A.

发明人： JORDI BOIRA BONHORA ,  DANIEL FLETA COIT ,  CARLOS ROURA SALIETTI

IPC分类号： A61L2/08 ,  A61L2/00 ,  B65B3/00 ,  B65B43/00 ,  B65B51/00 ,  B65B55/08

CPC分类号： A61L2/087 ,  A61L2/007 ,  B65B3/003 ,  B65B43/00 ,  B65B51/00 ,  B65B55/08 ,  A61L2202/181 ,  A61L2202/22 ,  A61L2202/23

摘要： A method is for sterilization of flexible bags containing human plasma protein solution with electron beam. The method includes emitting at least one electron beam with energy between 400 and 500 keV. After approximately 10 nsec to 1.5 sec, a second electron beam pulse is emitted with an energy of at least 4 MeV.

公开(公告)号：US20240058484A1

公开(公告)日：2024-02-22

申请号：US18269650

申请日：2021-12-14

申请人： Columbia Insurance Company

发明人： Richard Geurtsen

IPC分类号： A61L2/04 ,  A61L2/08 ,  A61L2/10 ,  A61L2/12 ,  A61L2/18 ,  C09D5/14

CPC分类号： A61L2/04 ,  A61L2/081 ,  A61L2/085 ,  A61L2/10 ,  A61L2/087 ,  A61L2/12 ,  A61L2/18 ,  C09D5/14

摘要： Disclosed herein are methods for pasteurizing or sterilizing architectural coating compositions using high pressure processing (HPP) with or without heat, radiation or other energy sources without additionally polymerizing the compositions, and storing same.

公开(公告)号：US20230405351A1

公开(公告)日：2023-12-21

申请号：US18332643

申请日：2023-06-09

申请人： Alucent Biomedical Inc.

发明人： James D. ISAACSON ,  RB Eugene HAYES ,  Dylan James BLAIR

IPC分类号： A61N5/06 ,  A61L2/08

CPC分类号： A61N5/062 ,  A61N5/0601 ,  A61L2202/24 ,  A61N2005/0602 ,  A61L2/087

摘要： An apparatus includes a catheter including light fibers extending from a proximal section to a distal section. The apparatus may include an emission section positioned on the distal section that is coated with an NVS agent. The material of the emission section may be different from the other sections of the catheter. The apparatus can be sterilized using E-beam sterilization.

公开(公告)号：US11766322B2

公开(公告)日：2023-09-26

申请号：US17509272

申请日：2021-10-25

申请人： Medtronic Vascular, Inc.

发明人： Niall Duffy ,  Stephen Montgomery

IPC分类号： A61F2/00 ,  A61F2/24 ,  A61L2/18 ,  A61L2/20 ,  A61L2/08 ,  A61L2/16

CPC分类号： A61F2/0095 ,  A61L2/087 ,  A61L2/16 ,  A61L2/206 ,  A61F2/2427 ,  A61L2202/21

摘要： Aspects of the disclosure relate to “wet” transcatheter prosthetic heart valve or other implant packaging and assemblies in which a prosthetic heart valve or other implant is loaded into a first portion of a delivery device and positioned within a container in which sterilizing fluid is retained to sterilize inside of the container as well as provide moisture to prevent the implant from drying out. The disclosure also relates to methods of sterilizing the disclosed assemblies. Some disclosed methods include at least two sterilizing steps and adjustment of a shaft seal or formation of multiple seals maintaining sterilizing fluid within the container so that areas underneath the shaft seal(s) can also be sterilized.

公开(公告)号：US11680164B2

公开(公告)日：2023-06-20

申请号：US17048571

申请日：2019-04-12

申请人： COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG

发明人： Derk Erich Wandner ,  Pierre Moulinie ,  Ralf Hufen

IPC分类号： A61L2/08 ,  C08L69/00 ,  C08L71/02 ,  C08K5/372 ,  A61L29/06 ,  A61L29/14

CPC分类号： C08L69/00 ,  A61L2/087 ,  A61L29/06 ,  A61L29/14 ,  C08K5/372 ,  C08L71/02 ,  A61L2202/181 ,  A61L2202/24 ,  C08L2201/08 ,  C08L69/00 ,  C08L71/02 ,  C08K5/372

摘要： The invention relates to a thermoplastic composition comprising A) aromatic polycarbonate, B) 0.1 to 5 wt.-% one or more polyether polyols and C) 0.01 to 0.30 wt.-% 3,3′-thiodipropionic acid. The invention also relates to medical technology products or parts of medical technology products consisting of such compositions as well as to a process for sterilization of such moulded parts by means of irradiation. The polycarbonate compositions according to the invention show significantly less yellowing after irradiation than known compositions and still have good mechanical properties.

公开(公告)号：US11667505B2

公开(公告)日：2023-06-06

申请号：US16611313

申请日：2018-05-08

申请人： Dai Nippon Printing Co., Ltd.

发明人： Atsushi Hayakawa

IPC分类号： A61L2/00 ,  B01J19/08 ,  B67C7/00 ,  A61L2/06 ,  A61L2/08 ,  A61L2/10 ,  A61L2/20 ,  A61L2/26 ,  B29C49/46 ,  B67C3/22 ,  B29L31/00

CPC分类号： B67C7/0073 ,  A61L2/06 ,  A61L2/087 ,  A61L2/10 ,  A61L2/208 ,  A61L2/26 ,  B29C49/46 ,  B67C3/22 ,  A61L2202/122 ,  A61L2202/17 ,  A61L2202/182 ,  A61L2202/23 ,  B29C2049/4635 ,  B29C2049/4664 ,  B29L2031/7158 ,  B67C2003/227 ,  B67C2003/228

摘要： An aseptic filling machine capable of performing molding and filling at the same time that has a compact facility size, requires a reduced initial investment, requires a reduced running cost because of its simplified process, and ensures an aseptic condition with reliability, and an aseptic filling method therefor. An aseptic filling machine includes a pre-heating sterilizing portion that sterilizes a preform, a heating portion that heats the sterilized preform, a molding and filling portion that fills the heated preform with a sterilized content under high pressure, thereby molding the preform into a bottle and at the same time filling the preform with the content, and a sealing portion that seals the bottle filled with the content. Before the aseptic filling machine starts operating, each portion is sterilized. During operation of the aseptic filling machine, aseptic air is supplied to each portion to maintain the aseptic condition.

公开(公告)号：US20190125906A1

公开(公告)日：2019-05-02

申请号：US16233403

申请日：2018-12-27

申请人： LIFE TECHNOLOGIES CORPORATION

发明人： Michael E. Goodwin ,  Nephi D. Jones ,  Bradley H. Buchanan

IPC分类号： A61L2/08 ,  A61L2/00 ,  A61L2/26

CPC分类号： A61L2/087 ,  A61L2/007 ,  A61L2/26

摘要： A container includes a first wall and an opposing second wall that extend between a first end and an opposing second end, a first fluid flow path being bounded between the first wall and the second wall. An inlet is formed at the first end and communicates with the first fluid flow path. An outlet is formed at the second end and communicates with the first fluid flow path. The first wall includes a primary wall portion having a first opening extending therethrough in alignment with the first fluid flow path. A secondary wall portion extends over the first opening and is secured to the primary wall portion so as to seal the first opening closed, the secondary wall portion being comprised of a film having a thickness that is less than a thickness of the primary wall portion.