ASSAYS FOR DETECTION OF PHENYLALANINE AMMONIA-LYASE AND ANTIBODIES TO PHENYLALANINE AMMONIA-LYASE
    132.
    发明申请
    ASSAYS FOR DETECTION OF PHENYLALANINE AMMONIA-LYASE AND ANTIBODIES TO PHENYLALANINE AMMONIA-LYASE 审中-公开
    检测苯丙氨酸氨基酸和苯丙氨酸氨基酸的抗体的测定

    公开(公告)号:US20110201022A1

    公开(公告)日:2011-08-18

    申请号:US13056606

    申请日:2009-07-30

    CPC classification number: G01N33/6854 G01N33/573 G01N2333/988

    Abstract: Provided herein are methods of detecting the presence of a pegylated enzyme, an enzyme-specific antibody (e.g., a neutralizing antibody or of a particular isotype), or a polyethylene glycol (PEG)-specific antibody in a sample, such as a bodily fluid or tissue of a patient. In certain embodiments, the enzyme is phenylalanine ammonia-lyase (PAL), such as Anabaena variabilis (Av) PAL administered to the patient as part of an enzyme substitution therapy for diseases or disorders, such as phenylketonuria (PKU), or cancer therapy.

    Abstract translation: 本文提供了检测样品中的聚乙二醇化酶,酶特异性抗体(例如中和抗体或特定同种型)或聚乙二醇(PEG)特异性抗体的存在的方法,例如体液 或组织。 在某些实施方案中,酶是苯丙氨酸氨裂解酶(PAL),例如作为用于诸如苯丙酮尿症(PKU)或癌症治疗的疾病或病症的酶替代疗法的一部分而施用于患者的变异鱼腥藻(Av)PAL。

    MAGNETIC RECORDING HEAD, HEAD GIMBAL ASSEMBLY, AND DISK DRIVE UNIT WITH THE SAME
    133.
    发明申请
    MAGNETIC RECORDING HEAD, HEAD GIMBAL ASSEMBLY, AND DISK DRIVE UNIT WITH THE SAME 有权
    磁性录音头,耳机总成及磁盘驱动单元

    公开(公告)号:US20110194209A1

    公开(公告)日:2011-08-11

    申请号:US12662503

    申请日:2010-04-20

    CPC classification number: G11B5/4853 Y10T428/1171 Y10T428/1193

    Abstract: A magnetic recording head includes a trailing surface and a plurality of bonding pads arranged on the trailing surface and in a row adapted for both bonding and testing. Each of the bonding pads has at least one side portion being coated with electrically conductive solder nonwettable coat to prevent short circuit between the adjacent bonding pads. The invention also discloses a head gimbal assembly with the magnetic recording head and a disk drive unit having such head gimbal assembly.

    Abstract translation: 磁记录头包括后表面和布置在后表面上并且适于粘合和测试的行中的多个接合焊盘。 每个接合焊盘具有涂覆有导电焊料不可润湿涂层的至少一个侧部,以防止相邻接合焊盘之间的短路。 本发明还公开了一种具有磁记录头的磁头万向架组件和具有这种磁头万向架组件的磁盘驱动单元。

    Transparent conductive nano-composites
    134.
    发明授权
    Transparent conductive nano-composites 有权
    透明导电纳米复合材料

    公开(公告)号:US07923922B2

    公开(公告)日:2011-04-12

    申请号:US11965651

    申请日:2007-12-27

    Abstract: The present invention, in one embodiment, provides a method of forming an organic electric device that includes providing a plurality of carbon nanostructures; and dispersing the plurality of carbon nanostructures in a polymeric matrix to provide a polymeric composite, wherein when the plurality of carbon nanostructures are present at a first concentration an interface of the plurality of carbon nanostructures and the polymeric matrix is characterized by charge transport when an external energy is applied, and when the plurality of carbon nanostructures are present at a second concentration the interface of the plurality of carbon nanostructures and the polymeric matrix are characterized by exciton dissociation when an external energy is applied, wherein the first concentration is less than the second concentration.

    Abstract translation: 本发明在一个实施方案中提供了一种形成有机电子器件的方法,该方法包括提供多个碳纳米结构; 以及将所述多个碳纳米结构分散在聚合物基质中以提供聚合物复合物,其中当所述多个碳纳米结构以第一浓度存在时,所述多个碳纳米结构和所述聚合物基体的界面的特征在于当外部 施加能量,并且当多个碳纳米结构以第二浓度存在时,当施加外部能量时,多个碳纳米结构和聚合物基体的界面的特征在于激子解离,其中第一浓度小于第二浓度 浓度。

    PULSE WIDTH MODULATION FREQUENCY CONVERSION
    135.
    发明申请
    PULSE WIDTH MODULATION FREQUENCY CONVERSION 有权
    脉冲宽度调制频率转换

    公开(公告)号:US20110032008A1

    公开(公告)日:2011-02-10

    申请号:US12537443

    申请日:2009-08-07

    CPC classification number: H03K7/08

    Abstract: A pulse width modulation (PWM) frequency converter converts an input PWM signal to an output PWM signal having a different frequency while maintaining a substantially equal duty ratio. The PWM frequency converter samples the input PWM signal for a PWM cycle using a sampling clock. A filter module filters the resulting set of one or more PWM parameters to compensate for noise introduced by potential clock mismatch, clock jitter, ambient variations, and other non-deterministic issues, thereby generating filtered PWM parameters. The sampling employed by the filter module compares a difference between the one or more current PWM parameters and previous (or historical) PWM parameters from an earlier sampled PWM cycle to a predetermined change threshold in determining a filtered set of one or more PWM parameters. The filtered set of one or more PWM parameters then is used to generate one or more corresponding PWM cycles of the output signal.

    Abstract translation: 脉冲宽度调制(PWM)频率转换器将输入PWM信号转换为具有不同频率的输出PWM信号,同时保持基本相等的占空比。 PWM变频器使用采样时钟对PWM周期的输入PWM信号进行采样。 滤波器模块对所产生的一个或多个PWM参数进行滤波,以补偿由潜在的时钟失配,时钟抖动,环境变化和其他非确定性问题引入的噪声,从而产生滤波后的PWM参数。 滤波器模块采用的采样将一个或多个当前PWM参数和先前(或历史)PWM参数之间的差异从较早采样的PWM周期与预定的变化阈值进行比较,以确定一个或多个PWM参数的滤波集合。 一个或多个PWM参数的经过滤波的组然后用于产生输出信号的一个或多个相应的PWM周期。

    LED driver with dynamic power management
    136.
    发明授权
    LED driver with dynamic power management 有权
    LED驱动器具有动态电源管理功能

    公开(公告)号:US07825610B2

    公开(公告)日:2010-11-02

    申请号:US12056237

    申请日:2008-03-26

    CPC classification number: H05B33/0827 H05B33/0815 Y02B20/347

    Abstract: Power management in a light emitting diode (LED) system having a plurality of LED strings is disclosed. A voltage source provides an output voltage to drive the LED strings. An LED driver monitors the tail voltages of the active LED strings to identify the minimum, or lowest, tail voltage and adjusts the output voltage of the voltage source based on the lowest tail voltage. The LED driver can adjust the output voltage so as to maintain the lowest tail voltage at or near a predetermined threshold voltage so as to ensure that the output voltage is sufficient to properly drive each active LED string with a regulated current in view of pulse width modulation (PWM) performance requirements without excessive power consumption.

    Abstract translation: 公开了具有多个LED串的发光二极管(LED)系统中的电源管理。 电压源提供输出电压来驱动LED串。 LED驱动器监视有源LED串的尾部电压,以识别最小或最低的尾部电压,并根据最低的尾部电压调节电压源的输出电压。 LED驱动器可以调节输出电压,以将最低的尾部电压保持在预定阈值电压处或接近预定阈值电压,以便确保输出电压足以根据脉宽调制来适当地驱动具有调节电流的每个有源LED串 (PWM)性能要求,而无需过多的功耗。

    Circuit for providing an approximately constant resistance and/or current and method therefor
    137.
    发明授权
    Circuit for providing an approximately constant resistance and/or current and method therefor 有权
    用于提供近似恒定的电阻和/或电流的电路及其方法

    公开(公告)号:US07804258B2

    公开(公告)日:2010-09-28

    申请号:US11929194

    申请日:2007-10-30

    Applicant: Bin Zhao

    Inventor: Bin Zhao

    CPC classification number: H05B33/0812 Y02B20/345

    Abstract: A circuit can provide an approximately constant resistance value that is virtually independent of process and temperature variations. A current control circuit may use a device that tracks the changes in a corresponding device over process and temperature variations. As a result, the behavior of device may be used to help determine the control information provided to device in order to maintain an approximately constant resistance Rm over process and temperature variations. The approximately constant resistance Rm may be used to provide an approximately constant current ILED. A wide variety of applications, not just LED drivers, may benefit from the use of an approximately constant resistance and/or current.

    Abstract translation: 电路可以提供几乎不变的过程和温度变化的近似恒定的电阻值。 电流控制电路可以使用跟踪过程和温度变化的对应装置中的变化的装置。 结果,可以使用装置的行为来帮助确定提供给装置的控制信息,以便在过程和温度变化上保持大致恒定的电阻Rm。 可以使用大致恒定的电阻Rm来提供近似恒定的电流ILED。 各种应用,不仅仅是LED驱动器,可能受益于使用近似恒定的电阻和/或电流。

    LED DRIVER WITH DYNAMIC HEADROOM CONTROL
    138.
    发明申请
    LED DRIVER WITH DYNAMIC HEADROOM CONTROL 有权
    LED驱动器与动态HEADROOM控制

    公开(公告)号:US20100194308A1

    公开(公告)日:2010-08-05

    申请号:US12363607

    申请日:2009-01-30

    CPC classification number: H05B33/0815 H05B33/0827 Y02B20/347

    Abstract: A voltage source provides an output voltage to drive a plurality of light emitting diode (LED) strings. A LED driver adjusts the level of the output voltage so as to maintain the lowest tail voltage of the LED strings at or near a predetermined threshold voltage so as provide sufficient headroom voltages for current regulators for the LED strings. The LED driver operates in an operational mode and a calibration mode, which can be implemented in parallel with, or part of, the operational mode. During the calibration mode, the LED driver determines, for each LED string, a code value representative of the level of the output voltage necessary to maintain the tail voltage of the corresponding LED string at or near the predetermined threshold voltage. In the operational mode, the code values from the calibration mode are used to control the voltage source to provide an appropriate level for the output voltage.

    Abstract translation: 电压源提供输出电压以驱动多个发光二极管(LED)串。 LED驱动器调节输出电压的电平,以便将LED串的最低尾电压保持在预定阈值电压处或接近预定阈值电压,以便为LED串的电流调节器提供足够的净空电压。 LED驱动器在操作模式和校准模式下操作,其可以与操作模式并行或部分实现。 在校准模式期间,LED驱动器针对每个LED串确定代表将相应LED串的尾部电压保持在或接近预定阈值电压所需的输出电压电平的代码值。 在操作模式下,来自校准模式的代码值用于控制电压源以为输出电压提供适当的电平。

    PEER-TO-PEER MESSAGING SYSTEM
    139.
    发明申请
    PEER-TO-PEER MESSAGING SYSTEM 审中-公开
    对等呼叫系统

    公开(公告)号:US20080250110A1

    公开(公告)日:2008-10-09

    申请号:US12059926

    申请日:2008-03-31

    Applicant: Bin Zhao

    Inventor: Bin Zhao

    Abstract: In one embodiment, a distributed environment for supporting on-line collaborative meetings among a plurality of users includes a plurality of applications executing on different client machines. A sequence of messages is transmitted from a first application of the distributed environment to a second application of the distributed environment, using a multicast form of delivery. A request for re-transmission is received from the second application specifying at least one message of the sequence that was not received by the second application. In response to the request, the specified at least one message of the sequence is retransmitted from the first application to the second application using a reliable unicast form of delivery.

    Abstract translation: 在一个实施例中,用于支持多个用户之间的在线协作会议的分布式环境包括在不同客户端机器上执行的多个应用程序。 使用多播形式的传送将消息序列从分布式环境的第一应用发送到分布式环境的第二应用。 从第二应用程序接收到重新发送的请求,指定序列的至少一个未被第二应用接收的消息。 响应于该请求,使用可靠的单播传送形式将序列的指定的至少一个消息从第一应用重新发送到第二应用。

    Voltage up-conversion circuit
    140.
    发明申请
    Voltage up-conversion circuit 有权
    电压上变频电路

    公开(公告)号:US20080246457A1

    公开(公告)日:2008-10-09

    申请号:US12157241

    申请日:2008-06-09

    Applicant: Bin Zhao

    Inventor: Bin Zhao

    CPC classification number: H02M3/07

    Abstract: According to one exemplary embodiment, a voltage up-conversion circuit includes a modulated voltage generator circuit, where the modulated voltage generator circuit is configured to receive an input voltage and generate a modulated voltage, and where the modulated voltage generator circuit includes at least one transistor. The voltage up-conversion circuit further includes a switching circuit coupled to the modulated voltage generator circuit, where the switching circuit is configured to couple the modulated voltage to a load capacitor when the modulated voltage is at a high level and decouple the modulated voltage to the load capacitor when the modulated voltage is at a low level. In the voltage up-conversion circuit, the load capacitor reaches a voltage greater a breakdown voltage of the at least one transistor in the modulated voltage generator circuit. The breakdown voltage can be a reliability breakdown voltage.

    Abstract translation: 根据一个示例性实施例,电压上变换电路包括调制电压发生器电路,其中调制电压发生器电路被配置为接收输入电压并产生调制电压,并且其中调制电压发生器电路包括至少一个晶体管 。 电压上变换电路还包括耦合到调制电压发生器电路的开关电路,其中开关电路被配置为当调制电压处于高电平时将调制电压耦合到负载电容器,并将调制电压去耦到 当调制电压处于低电平时加载电容。 在电压上变换电路中,负载电容器达到调制电压发生器电路中至少一个晶体管的击穿电压更大的电压。 击穿电压可以是可靠性击穿电压。

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