公开(公告)号：US07322491B2

公开(公告)日：2008-01-29

申请号：US11295251

申请日：2005-12-05

Applicant: Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

Inventor： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

IPC: B67B7/00

CPC classification number: B67D1/0004 ,  B65B39/004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/10 ,  B67D1/108 ,  B67D1/1279 ,  B67D3/04 ,  B67D2001/0827 ,  F04B43/1238 ,  F04B53/1037 ,  Y10T137/7761

Abstract: An apparatus has a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. A valve cover of the apparatus is formed of an elastic material and includes a cover base mounted on the valve body and fixedly secured against movement relative thereto, and a valve portion overlying the valve seat. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define a normally closed, axially-extending valve opening therebetween. The valve portion is movable between a normally closed position with the valve portion engaging the valve seat, and an open position with at least a segment of the valve portion spaced away from the valve seat to connect the valve opening in fluid communication with the flow aperture to thereby allow the passage of fluid from the flow aperture through the valve opening. A hermetically sealed variable-volume storage chamber stores therein multiple portions of the fluid and is connectible in fluid communication with the one-way valve assembly. A pump is coupled between the variable-volume storage chamber and the one-way valve assembly, and is configured to pump discrete portions of fluid from the variable-volume storage chamber, through the flow aperture, and through the valve opening to dispense the portions of fluid through the valve assembly.

Abstract translation: 一种装置具有限定第一通道，阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔的阀体。 该装置的阀盖由弹性材料形成，并且包括安装在阀体上的盖基座，并且固定地抵靠其相对移动，以及覆盖在阀座上的阀部分。 阀部分限定预定的径向厚度并与阀座形成过盈配合。 阀部分和阀座限定了其间的常闭的，轴向延伸的阀开口。 阀部分可以在与阀座接合的阀部分的常闭位置和打开位置之间移动，打开位置具有与阀座间隔开的阀部分的至少一段，以连接与开口流体连通的阀开口 从而允许流体从流动孔通过阀开口。 气密密封的可变容积储存室在其中存储有多个流体部分，并可与单向阀组件流体连通。 泵连接在可变容积存储室和单向阀组件之间，并且构造成从可变容积储存室通过流动孔泵送离散的流体部分，并且通过阀开口分配部分 的流体通过阀组件。

公开(公告)号：USD558061S1

公开(公告)日：2007-12-25

申请号：US29273719

申请日：2007-03-12

Applicant: Daniel Py ,  Julian V. Chan

Designer： Daniel Py ,  Julian V. Chan

公开(公告)号：US20070283666A1

公开(公告)日：2007-12-13

申请号：US11786206

申请日：2007-04-10

Applicant: Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willley

Inventor： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willley

IPC: B65B55/02

CPC classification number: A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

Abstract: A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

Abstract translation: 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：USD552798S1

公开(公告)日：2007-10-09

申请号：US29271877

申请日：2007-01-29

Applicant: Daniel Py ,  Julian V. Chan ,  Stephanie Ferreira ,  Luz Gladys Valencia

Designer： Daniel Py ,  Julian V. Chan ,  Stephanie Ferreira ,  Luz Gladys Valencia

公开(公告)号：US07270158B2

公开(公告)日：2007-09-18

申请号：US11510961

申请日：2006-08-28

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B1/04

CPC classification number: B65B7/161 ,  B65B3/003 ,  B65B7/00 ,  B65B37/06 ,  B65B43/54 ,  B65B51/22 ,  B65B55/04 ,  B65B55/08 ,  B65B57/00 ,  B65B65/02

Abstract: An apparatus is provided for needle filling and thermally resealing containers having stoppers that are needle penetrable for filling the containers with a substance, and are thermally resealable for thermally sealing a needle hole in the stopper upon withdrawal of a needle therefrom. A container support of the apparatus supports at least one container having a resealable stopper in a substantially fixed position during needle filling and thermally resealing a needle hole in the stopper upon withdrawal of a needle therefrom. A manifold is drivingly mounted over the container support and comprises (1) a needle cartridge including a needle for penetrating the resealable stopper and introducing a substance through the needle and into the container, a needle mount for mounting the needle cartridge on the manifold, and a needle cover releasably coupled to the needle mount for covering the needle during transportation, installation and/or removal of the needle cartridge from the manifold, and that is removable from the needle cartridge upon mounting the needle cartridge to the manifold. The manifold further includes a thermal source for heating a needle penetrated region of the stopper and, in turn, sealing a needle hole in the stopper.

Abstract translation: 提供了一种用于针头填充和热重新密封容器的装置，其具有用于针对物品填充容器的可穿刺的塞子，并且在从其中取出针时，可热再密封用于热封塞塞中的针孔。 装置的容器支撑件支撑至少一个具有可重新封闭的塞子的容器，该容器在针填充期间处于基本上固定的位置，并且在从针头中​​取出针时，在塞子中对针孔进行热再密封。 歧管被驱动地安装在容器支架上方，并且包括（1）针筒，其包括用于穿透可再密封塞子并将物质通过针引入容器的针，用于将针筒安装在歧管上的针座，以及 可拆卸地联接到针座的针罩，用于在从歧管运输，安装和/或移除针筒期间覆盖针头，并且当将针筒安装到歧管上时可从针筒上移除。 歧管还包括用于加热塞子的针穿入区域的热源，并且进而密封塞子中的针孔。

公开(公告)号：US20070156102A1

公开(公告)日：2007-07-05

申请号：US11714004

申请日：2007-03-05

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61M5/315

CPC classification number: A61M5/3129 ,  A61J1/2041 ,  A61J1/2044 ,  A61J1/2055 ,  A61J1/2093 ,  A61M5/1782 ,  A61M5/284 ,  A61M2005/3123

Abstract: A syringe and a reconstitution syringe are provided for the delivery of controlled doses of any of numerous different sterile substances, such as vaccines, medicaments, pharmaceutical preparations, cosmetics, and food products. A plunger of the syringe defines a resealable stopper frictionally and slidably received within a hollow syringe body for dispensing the medicament or other substance through a dispensing tip of the syringe upon movement of the plunger. The resealable stopper defines a heat-sealable portion to allow the stopper to be penetrated by a needle or other filling device to fill the syringe with a medicament or other substance, and in turn allow the hole remaining upon withdrawal of the needle to be heat sealed by transmission of laser energy thereon. The plunger assembly further defines a plurality of cam-like members that each engage and cooperate with a respective helical path of steps formed on the inner wall of the syringe body to provide stepwise movement of the plunger and, in turn, precise metering of the substance dispensed therefrom. A reconstitution syringe defines within a syringe body plural compartments, wherein each compartment stores a respective component of a multi-component medicament or other preparation. An elastomeric plug is coupled to the plunger and connected between the two compartments to prevent intermixing of the components. Upon moving the plunger, the plug is released to thereby place the compartments in fluid communication with each other, and to facilitate intermixing of the components upon shaking the syringe.

Abstract translation: 提供注射器和重组注射器用于递送受控剂量的许多不同的无菌物质，例如疫苗，药物，药物制剂，化妆品和食品中的任何一种。 注射器的柱塞限定了摩擦并可滑动地容纳在中空注射器主体内的可再密封塞子，用于在柱塞移动时通过注射器的分配尖端分配药物或其它物质。 可重新密封的止动件限定了可热封部分，以允许止动器被针或其他填充装置穿透，以用药物或其它物质填充注射器，并且进而允许在针头被热封时提供剩余的孔 通过在其上传输激光能量。 柱塞组件还限定多个凸轮状构件，每个凸轮状构件与形成在注射器主体的内壁上的步骤的相应螺旋路径接合并配合，以提供柱塞的逐步运动，并且进而精确地计量物质 从中分配。 重建注射器在注射器主体内限定多个隔室，其中每个隔室存储多组分药物或其它制剂的相应组分。 弹性塞连接到柱塞并连接在两个隔室之间以防止部件的混合。 在移动柱塞时，塞子被释放，从而将隔间彼此流体连通，并且有助于在振动注射器时组件的混合。

公开(公告)号：USD543469S1

公开(公告)日：2007-05-29

申请号：US29214062

申请日：2004-09-27

Applicant: Daniel Py ,  Gladys Luz-Valencia ,  Julian V. Chan

Designer： Daniel Py ,  Gladys Luz-Valencia ,  Julian V. Chan

公开(公告)号：US20070079896A1

公开(公告)日：2007-04-12

申请号：US11527775

申请日：2006-09-25

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65B1/04

CPC classification number: B65B3/04 ,  A61L2/08 ,  A61L2/087 ,  A61L2/24 ,  A61L2202/14 ,  B65B3/003 ,  B65B7/16 ,  B65B7/161 ,  B65B55/025 ,  B65B55/08 ,  B65B55/16

Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a heat resealable stopper and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the stopper and chamber for sterilizing the container. The previously sterilized containers are then transported through an e-beam chamber, wherein an electron beam is directed onto a penetrable surface of the stopper to sterilize the penetrable surface. A needle is mounted within the e-beam chamber and moved into engagement with the stopper to pierce the sterilized penetrable surface of the stopper and inject the substance through the needle and into the chamber of the container. The needle is then withdrawn from the stopper and the filled container is transported outside of the e-beam chamber. Laser energy is then transmitted onto the penetrated surface of the stopper to fuse the stopper material and hermetically re-seal the stopper.

Abstract translation: 提供了一种无菌灌装机及相关方法，用于无菌填充具有物质的容器。 容器包括可热再封塞的塞子和用于在其中容纳物质的腔室。 密封的空容器经受能够穿过塞子和室的辐射，以对容器进行灭菌。 先前灭菌的容器然后通过电子束室传送，其中电子束被引导到塞子的可穿透表面上以对可穿透表面进行消毒。 针安装在电子束室内并与止动器接合，以刺穿塞子的消毒的可渗透表面并将物质通过针头注入容器的腔室。 然后将针从止动器中取出，并将填充的容器运送到电子束室外部。 然后将激光能量传递到塞子的穿透表面上，以使塞子材料熔化并密封地重新密封塞子。

公开(公告)号：US20060131340A1

公开(公告)日：2006-06-22

申请号：US11301659

申请日：2005-12-12

Applicant: Daniel Py ,  Julian Chan

Inventor： Daniel Py ,  Julian Chan

IPC: B65D37/00

CPC classification number: B65D35/46 ,  B65D47/205 ,  B65D47/2056 ,  B65D47/2081

Abstract: A container and valve assembly for storing and dispensing substances including edible substances. The container is a tubular body that defines a storage chamber for storing the substance and a head portion for supports the valve assembly. The valve assembly includes a valve body and a valve seat surrounded by a flexible outer cover that includes a valve portion. A seem between the valve portion and valve seat form a one-way release valve wherein a portion of the seam remains closed when the substance is dispensed. To dispense the substance, pressure is applied to the body forcing the substance into the valve assembly, which in turn, controls the flow and release of the substance without exposing the remaining substance to the external atmosphere; thus, the sterility of the storage chamber and remaining substance is maintained, and the shelf life of the substance is increased.

公开(公告)号：USD521638S1

公开(公告)日：2006-05-23

申请号：US29193803

申请日：2003-11-14

Applicant: Daniel Py ,  Julian V. Chan

Designer： Daniel Py ,  Julian V. Chan