公开(公告)号：US20230060052A1

公开(公告)日：2023-02-23

申请号：US17864684

申请日：2022-07-14

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Timothy C. Aarons ,  Daniel S. Flo

IPC: A61B5/00 ,  A61B5/36

Abstract: A system for accounting for adverse pacing artifacts may include an electrode apparatus and a computing apparatus. The electrode apparatus may include one or more external electrodes to monitor electrical activity from tissue of a patient. The computing apparatus may include one or more processors and may be operatively coupled to the electrode apparatus. The computing apparatus may be configured to monitor electrical activity from the tissue of the patient using the one or more external electrodes. Such electrical activity may be used to generate one or more cardiac signals of the patient over time. The computing apparatus may detect a pacing artifact in the one or more cardiac signals and determine whether to account for, and account for, the pacing artifact based on a pacing artifact characteristic of the pacing artifact when producing electrical heterogeneity information.

公开(公告)号：US11471678B2

公开(公告)日：2022-10-18

申请号：US16047619

申请日：2018-07-27

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  D'Anne E. Kudlik ,  Karen J. Kleckner ,  Melissa M. Rhodes ,  Keelia Doyle

IPC: A61B5/318 ,  A61N1/36 ,  A61B5/00 ,  A61N1/362 ,  A61N1/365 ,  A61B5/282 ,  A61B5/287 ,  A61B5/352 ,  A61B5/366 ,  A61N1/32 ,  A61N1/368 ,  A61B5/25 ,  A61B5/316 ,  A61B5/363 ,  A61B5/364 ,  A61N1/39

Abstract: Systems and methods are described herein for selection of a cardiac cycle, or heartbeat, from a plurality of cardiac cycles monitored over time. The cardiac cycle may be selected using various metrics including a single-cycle metric and a cycle-series metric. Further, the selected cardiac cycle may be used for further cardiac analysis (for example, to generate electrical activation times).

公开(公告)号：US20220168576A1

公开(公告)日：2022-06-02

申请号：US17521277

申请日：2021-11-08

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/37

Abstract: Systems and methods are described herein related to the evaluation and adjustment of left bundle branch (LBB) pacing therapy. Evaluation of the LBB pacing therapy may utilize electrical activity monitored from a plurality of external electrodes. The electrical activity may be used to provided one or more metrics of dispersion of surrogate cardiac electrical activation times, which may then be used to evaluate, and potentially adjust the LBB pacing therapy.

公开(公告)号：US20220161035A1

公开(公告)日：2022-05-26

申请号：US17670195

申请日：2022-02-11

Applicant: Medtronic, Inc.

Inventor： Berthold Stegemann ,  Richard Cornelussen ,  Joeri Heynens ,  Subham Ghosh

IPC: A61N1/368 ,  A61B5/363 ,  A61B5/364 ,  A61N1/39 ,  A61N1/05 ,  A61N1/362 ,  A61N1/365

Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first and second left ventricular electrodes spatially separated from one another and a right ventricular electrode, all coupled to an implantable pulse generator. The processing circuit coupled to the implantable pulse generator, the processing circuit configured to determine whether a prospective heart failure condition has occurred and if so to trigger the pulse generator to switch from a first pacing mode to a second pacing mode, the first pacing mode comprising delivering only a first pacing pulse to a left ventricle (LV) and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle and the second pacing mode comprising delivering first and a second pacing pulses to the LV and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle.

公开(公告)号：US20220111217A1

公开(公告)日：2022-04-14

申请号：US17559092

申请日：2021-12-22

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/37 ,  A61N1/05 ,  A61N1/365 ,  A61N1/368

Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.

公开(公告)号：US11291845B2

公开(公告)日：2022-04-05

申请号：US16791661

申请日：2020-02-14

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/37 ,  A61N1/365 ,  A61N1/372 ,  A61N1/39

Abstract: In a medical device system, a computer apparatus is configured to receive body surface electrical signals from an electrode apparatus including multiple external electrodes. The computing apparatus generates electrical dyssynchrony data from the body surface electrical signals during delivery of His bundle pacing pulses and identifies effective His bundle capture based on the electrical dyssynchrony data. The computing apparatus generates an indication of His bundle capture in response to identifying the effective His bundle capture.

公开(公告)号：US20220032062A1

公开(公告)日：2022-02-03

申请号：US17360648

申请日：2021-06-28

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/368 ,  A61N1/37 ,  A61N1/375

Abstract: The present disclosure relates generally to pacing of the cardiac conduction system of a patient, and more particularly, to providing adaptive cardiac conducting system pacing therapy and to determining selective or non-selective capture of the cardiac conduction system by cardiac conduction system pacing therapy. The adaptive cardiac conduction system pacing therapy may adjust AV delay and VV delay based on various signals and metrics and may switch between cardiac conduction system pacing therapy exclusively and cardiac conduction system pacing therapy in combination with traditional left ventricular pacing therapy.

公开(公告)号：US20210308458A1

公开(公告)日：2021-10-07

申请号：US17193794

申请日：2021-03-05

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/362 ,  A61N1/04 ,  A61N1/36 ,  A61N1/37

Abstract: Systems and methods are described herein for determining whether a patient's cardiac conduction system or portions thereof are engaged by cardiac conduction system pacing therapy. One or more local metrics of electrical heterogeneity information may be generated based on surrogate cardiac electrical measured using a plurality of local external electrodes, which may be used to determine whether the patient's cardiac conduction system is engaged.

公开(公告)号：US20210307670A1

公开(公告)日：2021-10-07

申请号：US17193801

申请日：2021-03-05

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61B5/367 ,  A61B5/282 ,  A61B5/00 ,  A61B5/339

Abstract: Systems and methods are described herein for determining whether cardiac conduction system pacing therapy may be beneficial and/or determining how proximal or distal a cardiac conduction system block may be using external cardiac signals. To do so, one or more left-sided metrics of electrical heterogeneity information may be generated based on left-sided surrogate cardiac electrical measured using a plurality of left external electrodes

公开(公告)号：US11027137B2

公开(公告)日：2021-06-08

申请号：US16152078

申请日：2018-10-04

Applicant: Medtronic, Inc.

Inventor： Richard M. T. Lu ,  Subham Ghosh ,  Robert W. Stadler

IPC: A61N1/37 ,  A61N1/362 ,  A61N1/368 ,  A61B5/361

Abstract: The present disclosure pertains to cardiac pacing methods and systems, and, more particularly, to cardiac resynchronization therapy (CRT). In particular, the present disclosure pertains to determining whether a patient is experiencing atrial fibrillation (AF). If the patient is experiencing AF, the efficacy of CRT is determined. A signal is sensed in response to a ventricular pacing stimulus. Through signal processing, a number of features are parsed from the signal and a determination is made as to whether the ventricular pacing stimulus evoked a response from the ventricle.