公开(公告)号：US20100142787A1

公开(公告)日：2010-06-10

申请号：US12630061

申请日：2009-12-03

申请人： Yefeng Zheng ,  Bogdan Georgescu ,  Arne Littmann ,  Edgar Mueller ,  Dorin Comaniciu

发明人： Yefeng Zheng ,  Bogdan Georgescu ,  Arne Littmann ,  Edgar Mueller ,  Dorin Comaniciu

IPC分类号： G06K9/62

CPC分类号： G06K9/3241 ,  G06K2209/051 ,  G06T7/11 ,  G06T7/143 ,  G06T2207/10088 ,  G06T2207/20081 ,  G06T2207/30048

摘要： A method and system for left ventricle (LV) detection in 2D magnetic resonance imaging (MRI) images is disclosed. In order to detect the LV in a 2D MRI image, a plurality of LV candidates are detected, for example using marginal space learning (MSL) based detection. Candidates for distinctive anatomic landmarks associated with the LV are then detected in the 2D MRI image. In particular, apex candidates and base candidates are detected in the 2D MRI image. One of the LV candidates is selected as a final LV detection result by ranking the LV candidates based on the LV candidates, the apex candidates, and the base candidates using a trained ranking model.

摘要翻译： 公开了一种用于2D磁共振成像（MRI）图像中左心室（LV）检测的方法和系统。 为了检测2D MRI图像中的LV，例如使用基于边缘空间学习（MSL）的检测来检测多个LV候选。 然后在2D MRI图像中检测与LV相关的特征性解剖学标记的候选者。 特别地，在2D MRI图像中检测到顶点候选和基础候选。 通过使用训练排名模型，基于LV候选，顶点候选和基础候选对LV候选进行排名，将LV候选者中的一个选择为最终的LV检测结果。

公开(公告)号：US20080214923A1

公开(公告)日：2008-09-04

申请号：US11945325

申请日：2007-11-27

申请人： Gunnar Krueger ,  Arne Littmann

发明人： Gunnar Krueger ,  Arne Littmann

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/11 ,  A61B5/7207 ,  G01R33/3415 ,  G01R33/56509 ,  G01R33/5673 ,  G01R33/5676

摘要： In a method and magnetic resonance (MR) apparatus for determination of movement of an examination subject during the acquisition of (MR) measurement data using at least two antenna elements that exhibit respectively different spatial positions, after each radiated excitation pulse a navigator signal is acquired in the measurement data and movement of the examination subject between two excitation pulses during the acquisition of the measurement data is determined from a change of the signal strength of the navigator signal in the at least two antenna elements and based on the respective spatial positions of the antenna elements.

摘要翻译： 在用于使用至少两个呈现分别不同的空间位置的天线元件获取（MR）测量数据期间确定检查对象的移动的方法和磁共振（MR）装置中，在每个辐射的激励脉冲之后，获取导航信号 在测量数据和测量数据获取期间的两个激励脉冲之间的测试对象的移动是根据至少两个天线元件中的导航信号的信号强度的变化，并且基于相应的空间位置 天线元件

公开(公告)号：US20080159607A1

公开(公告)日：2008-07-03

申请号：US11769821

申请日：2007-06-28

申请人： Arne Littmann

发明人： Arne Littmann

IPC分类号： G06K9/00

CPC分类号： A61B6/463 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/4088 ,  A61B6/03 ,  A61B34/10 ,  A61B2090/374 ,  G06T7/30

摘要： In a method for evaluation of two images of an organ system acquired at different points in time to establish a pathological variation, the organ system exhibits a first region and a second region that are present in and that are differentiated in each of the images, with the second region of the pathological variation being acquired more strongly than the first region. A registration is determined that causes the respective first region in two images to be in registration with each other. Imaging system-dependent differences, in particular deformations, are determined and compensated between the two images. After an extension of the registration such that the second region is encompassed as well by the extended registration, via a transformation one of the two images to the other can be made, presented and/or stored that includes the second region, using the extended registration. A medical imaging system with a computer can implement the method.

摘要翻译： 在用于评估在不同时间点获得的器官系统的两个图像以建立病理变化的方法中，器官系统呈现存在于每个图像中且在每个图像中区分的第一区域和第二区域，其中， 病理变异的第二区域被获得比第一区域更强烈。 确定使两个图像中的相应第一区域彼此对准的登记。 在两个图像之间确定和补偿成像系统相关的差异，特别是变形。 在扩展注册之后，通过扩展注册也包含第二区域，通过使用扩展注册可以使两个图像中的一个图像彼此之一变形，呈现和/或存储，包括第二区域 。 具有计算机的医学成像系统可以实现该方法。

公开(公告)号：US08805045B2

公开(公告)日：2014-08-12

申请号：US13248309

申请日：2011-09-29

申请人： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Arne Littmann ,  Manuela Rick ,  Michaela Schmidt ,  Hui Xue

发明人： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Arne Littmann ,  Manuela Rick ,  Michaela Schmidt ,  Hui Xue

IPC分类号： G06K9/00 ,  G06T7/00

CPC分类号： G06T7/0083 ,  G06T7/12 ,  G06T7/174 ,  G06T2207/10016 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/20104 ,  G06T2207/30004

摘要： A method for identifying a region of interest within a time sequence of images includes acquiring a time sequence of images comprising a plurality of image frames. Image segmentation is performed to segment a region of interest (ROI) from within each of the plurality of image frames of the time sequence of images. Manual edits are received for the ROI within one or more of the plurality of image frames. The manual edits are propagated to other image frames of the plurality of images. An extent to which each of the manual edits are propagated to other image frames is dependent upon a transformation function or deformation field used to propagate the manual edits and a weighing factor that is influenced by a distance in time between the other image frames and the frames that have been manually edited.

摘要翻译： 用于识别图像的时间序列内的感兴趣区域的方法包括获取包括多个图像帧的图像的时间序列。 执行图像分割以从图像的时间序列的多个图像帧的每一个内分割感兴趣区域（ROI）。 对于多个图像帧中的一个或多个中的ROI，接收手动编辑。 手动编辑被传播到多个图像的其他图像帧。 每个手动编辑传播到其他图像帧的程度取决于用于传播手动编辑的变换函数或变形字段以及受其他图像帧和帧之间的时间距离的影响的称重因子 已经被手动编辑。

公开(公告)号：US08269495B2

公开(公告)日：2012-09-18

申请号：US12571540

申请日：2009-10-01

申请人： Arne Littmann ,  Peter Speier ,  Katrin Christel Sprung

发明人： Arne Littmann ,  Peter Speier ,  Katrin Christel Sprung

IPC分类号： G01V3/00

CPC分类号： A61B5/055 ,  A61B5/7285 ,  G01R33/281 ,  G01R33/56 ,  G01R33/5601 ,  G01R33/5602 ,  G01R33/5608 ,  G01R33/563 ,  G01R33/56325 ,  G01R33/56366

摘要： In a method to determine an inversion time value for contrast improvement between different tissue in a contrast agent-supported magnetic resonance imaging, a series of magnetic resonance images of an imaging area is acquired using an inversion recovery sequence with different inversion times. A structure in the magnetic resonance images is segmented and a time response of the signal intensity of image elements corresponding to one another in the magnetic resonance images of the segmented structure is automatically determined. Minima of the signal intensity in the segmented structure are determined automatically and associated with the associated inversion time values. The optimal inversion time value for contrast improvement is automatically determined from the inversion time values that have been associated with the minima of the signal intensity in the segmented structure.

摘要翻译： 在用于确定造影剂支持的磁共振成像中不同组织之间的对比度改善的反转时间值的方法中，使用具有不同反转时间的反转恢复序列来获取成像区域的一系列磁共振图像。 分割磁共振图像中的结构，并且自动确定在分段结构的磁共振图像中彼此对应的图像元素的信号强度的时间响应。 自动确定分段结构中的信号强度的最小值，并与相关的反转时间值相关联。 根据与分段结构中的信号强度的最小值相关联的反转时间值自动确定对比度改善的最佳反演时间值。

公开(公告)号：US20100085051A1

公开(公告)日：2010-04-08

申请号：US12571540

申请日：2009-10-01

申请人： Arne Littmann ,  Peter Speier ,  Katrin Christel Sprung

发明人： Arne Littmann ,  Peter Speier ,  Katrin Christel Sprung

IPC分类号： G01R33/48

CPC分类号： A61B5/055 ,  A61B5/7285 ,  G01R33/281 ,  G01R33/56 ,  G01R33/5601 ,  G01R33/5602 ,  G01R33/5608 ,  G01R33/563 ,  G01R33/56325 ,  G01R33/56366

摘要： In a method to determine an inversion time value for contrast improvement between different tissue in a contrast agent-supported magnetic resonance imaging, a series of magnetic resonance images of an imaging area is acquired using an inversion recovery sequence with different inversion times. A structure in the magnetic resonance images is segmented and a time response of the signal intensity of image elements corresponding to one another in the magnetic resonance images of the segmented structure is automatically determined. Minima of the signal intensity in the segmented structure are determined automatically and associated with the associated inversion time values. The optimal inversion time value for contrast improvement is automatically determined from the inversion time values that have been associated with the minima of the signal intensity in the segmented structure.

摘要翻译： 在用于确定造影剂支持的磁共振成像中的不同组织之间的对比度改善的反转时间值的方法中，使用具有不同反转时间的反转恢复序列来获取成像区域的一系列磁共振图像。 分割磁共振图像中的结构，并且自动确定在分段结构的磁共振图像中彼此对应的图像元素的信号强度的时间响应。 自动确定分段结构中的信号强度的最小值，并与相关的反转时间值相关联。 根据与分段结构中的信号强度的最小值相关联的反转时间值自动确定对比度改善的最佳反演时间值。

公开(公告)号：US09402561B2

公开(公告)日：2016-08-02

申请号：US11945325

申请日：2007-11-27

申请人： Gunnar Krueger ,  Arne Littmann

发明人： Gunnar Krueger ,  Arne Littmann

IPC分类号： A61B5/11 ,  A61B5/055 ,  A61B5/00 ,  G01R33/3415 ,  G01R33/565 ,  G01R33/567

CPC分类号： A61B5/055 ,  A61B5/11 ,  A61B5/7207 ,  G01R33/3415 ,  G01R33/56509 ,  G01R33/5673 ,  G01R33/5676

摘要： In a method and magnetic resonance (MR) apparatus for determination of movement of an examination subject during the acquisition of (MR) measurement data using at least two antenna elements that exhibit respectively different spatial positions, after each radiated excitation pulse a navigator signal is acquired in the measurement data and movement of the examination subject between two excitation pulses during the acquisition of the measurement data is determined from a change of the signal strength of the navigator signal in the at least two antenna elements and based on the respective spatial positions of the antenna elements.

摘要翻译： 在用于使用至少两个呈现分别不同的空间位置的天线元件获取（MR）测量数据期间确定检查对象的移动的方法和磁共振（MR）装置中，在每个辐射的激励脉冲之后，获取导航信号 在测量数据和测量数据获取期间的两个激励脉冲之间的测试对象的移动是根据至少两个天线元件中的导航信号的信号强度的变化，并且基于相应的空间位置 天线元件

公开(公告)号：US08811699B2

公开(公告)日：2014-08-19

申请号：US13234694

申请日：2011-09-16

申请人： Xiaoguang Lu ,  Jens Gühring ,  Hui Xue ,  Marie-Pierre Jolly ,  Christoph Guetter ,  Bogdan Georgescu ,  Sven Zuehlsdorff ,  Arne Littmann

发明人： Xiaoguang Lu ,  Jens Gühring ,  Hui Xue ,  Marie-Pierre Jolly ,  Christoph Guetter ,  Bogdan Georgescu ,  Sven Zuehlsdorff ,  Arne Littmann

IPC分类号： G06K9/00

CPC分类号： G06K9/4609 ,  G06K2209/051 ,  G06T7/11 ,  G06T7/143 ,  G06T7/194 ,  G06T2207/10088 ,  G06T2207/20164 ,  G06T2207/30048

摘要： A method including receiving an image sequence, wherein the image sequence includes a plurality of two-dimensional (2D) image frames of an organ arranged in a time sequence; constructing a three-dimensional (3D) volume by stacking a plurality of the 2D image frames in time order; detecting a best bounding box for a target of interest in the 3D volume, wherein the best bounding box is specified by a plurality of parameters including spatial and temporal information contained in the 3D volume; and determining the target of interest from the best bounding box.

摘要翻译： 一种包括接收图像序列的方法，其中所述图像序列包括以时间顺序排列的器官的多个二维（2D）图像帧; 通过以时间顺序堆叠多个2D图像帧来构造三维（3D）体积; 检测所述3D体积中感兴趣的目标的最佳边界框，其中所述最佳边界框由包括在所述3D体积中的空间和时间信息的多个参数指定; 并从最佳边界框确定感兴趣的目标。

公开(公告)号：US08340385B2

公开(公告)日：2012-12-25

申请号：US12630061

申请日：2009-12-03

申请人： Yefeng Zheng ,  Bogdan Georgescu ,  Arne Littmann ,  Edgar Mueller ,  Dorin Comaniciu

发明人： Yefeng Zheng ,  Bogdan Georgescu ,  Arne Littmann ,  Edgar Mueller ,  Dorin Comaniciu

IPC分类号： G06K9/00

CPC分类号： G06K9/3241 ,  G06K2209/051 ,  G06T7/11 ,  G06T7/143 ,  G06T2207/10088 ,  G06T2207/20081 ,  G06T2207/30048

摘要： A method and system for left ventricle (LV) detection in 2D magnetic resonance imaging (MRI) images is disclosed. In order to detect the LV in a 2D MRI image, a plurality of LV candidates are detected, for example using marginal space learning (MSL) based detection. Candidates for distinctive anatomic landmarks associated with the LV are then detected in the 2D MRI image. In particular, apex candidates and base candidates are detected in the 2D MRI image. One of the LV candidates is selected as a final LV detection result by ranking the LV candidates based on the LV candidates, the apex candidates, and the base candidates using a trained ranking model.

摘要翻译： 公开了一种用于2D磁共振成像（MRI）图像中左心室（LV）检测的方法和系统。 为了检测2D MRI图像中的LV，例如使用基于边缘空间学习（MSL）的检测来检测多个LV候选。 然后在2D MRI图像中检测与LV相关的特征性解剖学标记的候选者。 特别地，在2D MRI图像中检测到顶点候选和基础候选。 通过使用训练排名模型，基于LV候选，顶点候选和基础候选对LV候选进行排名，将LV候选者中的一个选择为最终的LV检测结果。

公开(公告)号：US20120087561A1

公开(公告)日：2012-04-12

申请号：US13248309

申请日：2011-09-29

申请人： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Arne Littmann ,  Manuela Rick ,  Michaela Schmidt ,  Hui Xue

发明人： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Arne Littmann ,  Manuela Rick ,  Michaela Schmidt ,  Hui Xue

IPC分类号： G06K9/46

CPC分类号： G06T7/0083 ,  G06T7/12 ,  G06T7/174 ,  G06T2207/10016 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/20104 ,  G06T2207/30004

摘要： A method for identifying a region of interest within a time sequence of images includes acquiring a time sequence of images comprising a plurality of image frames. Image segmentation is performed to segment a region of interest (ROI) from within each of the plurality of image frames of the time sequence of images. Manual edits are received for the ROI within one or more of the plurality of image frames. The manual edits are propagated to other image frames of the plurality of images. An extent to which each of the manual edits are propagated to other image frames is dependent upon a transformation function or deformation field used to propagate the manual edits and a weighing factor that is influenced by a distance in time between the other image frames and the frames that have been manually edited.

摘要翻译： 用于识别图像的时间序列内的感兴趣区域的方法包括获取包括多个图像帧的图像的时间序列。 执行图像分割以从图像的时间序列的多个图像帧的每一个内分割感兴趣区域（ROI）。 对于多个图像帧中的一个或多个中的ROI，接收手动编辑。 手动编辑被传播到多个图像的其他图像帧。 每个手动编辑传播到其他图像帧的程度取决于用于传播手动编辑的变换函数或变形字段以及受其他图像帧和帧之间的时间距离的影响的称重因子 已经被手动编辑。