公开(公告)号：US12121370B2

公开(公告)日：2024-10-22

申请号：US16921416

申请日：2020-07-06

Applicant: Covidien LP

Inventor： Dean Montgomery ,  Paul S. Addison ,  Peter Galen

IPC: A61B5/00 ,  A61B5/021 ,  A61B5/1455 ,  G16H50/30

CPC classification number: A61B5/7275 ,  A61B5/021 ,  A61B5/14551 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/7246 ,  G16H50/30

Abstract: A system for monitoring autoregulation includes an oxygen saturation sensor configured to obtain an oxygen saturation signal indicative of an oxygen saturation of a patient. The system also includes a controller having a processor configured to receive a blood pressure signal indicative of a blood pressure of the patient and the oxygen saturation signal, determine a change in the oxygen saturation signal and a change in the blood pressure signal over a period of time, and provide an indication that the patient's autoregulation is intact if the oxygen saturation changes by more than an oxygen saturation threshold and if the blood pressure changes by less than a blood pressure threshold during the period of time.

公开(公告)号：US20240346657A1

公开(公告)日：2024-10-17

申请号：US18291522

申请日：2022-07-21

Applicant: OXFORD BRAIN DIAGNOSTICS LTD

Inventor： Ian HARDINGHAM

IPC: G06T7/00 ,  A61B5/00 ,  G06T7/73 ,  G16H20/70

CPC classification number: G06T7/0014 ,  A61B5/4064 ,  G06T7/74 ,  G16H20/70 ,  A61B5/0042 ,  G06T2207/10088 ,  G06T2207/30016 ,  G06T2207/30204

Abstract: Systems, methods (300), computer program products, and computer readable media for processing images of brains are described. Techniques are described for transforming, into a common space, reference points obtained from at least one image of a reference brain in a first space (302), transforming, into the common space, test points obtained from at least one image of a test brain in a second space (304), determining a position of each of the transformed reference points and each of the transformed test points in the common space (306), calculating a displacement of each of the transformed test points relative to each of the transformed reference points based on the determined positions (308), determining a correspondence between one of the transformed test points and a given transformed reference point based on the calculated displacements (310), and determining a corresponding test point in the second space to a reference point in the first space based on the determined correspondence (312).

公开(公告)号：US20240341695A1

公开(公告)日：2024-10-17

申请号：US18609211

申请日：2024-03-19

Applicant: Tiposi, Inc.

Inventor： Fuhao Li ,  Lijun Zhang ,  Shih Hsiung Mo

IPC: A61B5/00 ,  A61B5/0507

CPC classification number: A61B5/7267 ,  A61B5/0042 ,  A61B5/0507 ,  A61B5/4064 ,  A61B5/6803 ,  A61B5/7257 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B2562/0228

Abstract: Embodiments of a system for training a classification neural network are provided. The system is configured to receive a first set of simulated bioelectric signals and patient bioelectric signals from a first computing device and a second set of simulated bioelectric signals from a second computing device, generate a compensation factor for the second computing device based on the first set of simulated bioelectric signals and the second set of simulated bioelectric signals, generate compensated patient bioelectric signals based on the compensation factor and the patient bioelectric signals, and train the classification neural network based on the compensated patient bioelectric signals, the second set of simulated bioelectric signals and the compensation factor. The classification neural network is trained to predict a classification label for each of one or more bioelectric signals.

公开(公告)号：US20240341681A1

公开(公告)日：2024-10-17

申请号：US18750746

申请日：2024-06-21

Applicant: CEREBROTECH MEDICAL SYSTEMS, INC.

Inventor： Richard Warren WYETH ,  Mitchell Elliott LEVINSON ,  Bryan Jon WEBER

IPC: A61B5/00 ,  A61B5/03 ,  A61B5/05 ,  A61B5/0522 ,  A61B5/245 ,  A61B6/03 ,  G16H40/67 ,  G16H50/20

CPC classification number: A61B5/4875 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0042 ,  A61B5/031 ,  A61B5/05 ,  A61B5/0522 ,  A61B5/245 ,  A61B5/4064 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4878 ,  A61B5/6803 ,  A61B5/6814 ,  A61B5/721 ,  A61B5/7214 ,  A61B5/7225 ,  A61B5/7257 ,  A61B5/7275 ,  A61B5/7282 ,  A61B6/032 ,  G16H40/67 ,  G16H50/20 ,  A61B2560/0223 ,  A61B2562/0223 ,  A61B2562/166 ,  A61B2562/182 ,  A61B2562/222 ,  A61B2576/026

Abstract: A device for detecting spatial differences in fluid level changes in a tissue of a patient may include a support structure for securing the device to a body part of the patient, a processing element operably connected to the support structure, a wireless networking interface operably connected to the support structure and in communication with the processing element and an external computing device via a network, a first transmission module operably connected to the support structure and in communication with the processing element, a second transmission module and a third transmission module operably connected to the support structure and in communication with the processing element. When activated, the first transmission module transmits a first time varying magnetic field through the tissue of the patient. The second and third transmission modules, which are spatially separated from one another, receive first and second versions, respectively, of the first time varying magnetic field.

公开(公告)号：US12111324B2

公开(公告)日：2024-10-08

申请号：US17046116

申请日：2019-04-09

Applicant: QUANTERIX CORPORATION

Inventor： Edward Kevin Hrusovsky ,  David Wilson ,  Dandan Shan ,  Lei Chang ,  Linan Song ,  Andreas Jeromin ,  Carmen Ioana Tobos ,  Purvish Prahlad Patel

IPC: G01N33/68 ,  A61B5/00 ,  G01N1/38 ,  G01N33/58

CPC classification number: G01N33/6896 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0082 ,  A61B5/4064 ,  G01N1/38 ,  G01N33/582 ,  G01N2001/386 ,  G01N2800/28 ,  G01N2800/2821 ,  G01N2800/285

Abstract: The present disclosure relates to digital immunoassays performed on diluted samples obtained from dried blood spots, for example dried capillary blood samples, to detect the presence or absence of a physiological condition by quantifying one or a combination of biomarkers at concentrations indicative of the condition.

公开(公告)号：US12089946B1

公开(公告)日：2024-09-17

申请号：US16358793

申请日：2019-03-20

Applicant: UNIVERSITY OF SOUTH FLORIDA

Inventor： Theresa Ann Zesiewicz ,  Kyle Brandon Reed

IPC: A61B5/00

CPC classification number: A61B5/4076 ,  A61B5/4064 ,  A61B5/4824 ,  A61B5/6826 ,  A61B5/0048

Abstract: In one embodiment, a system for finger-to-thumb crease testing includes a patient interface configured to attach to a thumb of a patient, the patient interface including a touch sensor configured to sense contact between a finger of the patient and the touch sensor, the touch sensor being positioned on the patient interface in a location at which it overlies a distalmost thumb crease of the thumb when the patient interface is attached, and a control module in electrical communication with the patient interface, the control module being configured to count a number of times the patient successfully taps the touch sensor with the finger.

公开(公告)号：US20240293088A1

公开(公告)日：2024-09-05

申请号：US18574287

申请日：2022-08-30

Applicant: The Board of Trustees of the Leland Stanford Junior University

Inventor： Yuhao Huang ,  Casey Halpern ,  Jonathon Parker ,  Rajat Shivacharan ,  Jeffrey B. Wang

IPC: A61B5/00 ,  A61B5/145

CPC classification number: A61B5/7278 ,  A61B5/14532 ,  A61B5/4064 ,  A61B5/4839 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/746

Abstract: Systems and methods for predictive glucose in accordance with embodiments of the invention are illustrated. One embodiment includes glucose management device, including a brain signal recorder, and a controller, including a processor, and a memory, the memory containing a glucose monitoring application configured to direct the processor to record a brain activity signal of a user's brain using the brain signal recorder, and decode the brain activity signal to predict future glucose levels of the patient.

公开(公告)号：US20240293058A1

公开(公告)日：2024-09-05

申请号：US18545661

申请日：2023-12-19

Applicant: Neuro Kinetics, Inc.

Inventor： Alexander D. Kiderman ,  Ian Shirey

IPC: A61B5/16 ,  A61B3/00 ,  A61B3/113 ,  A61B5/00 ,  A61B5/12

CPC classification number: A61B5/162 ,  A61B3/0025 ,  A61B3/0041 ,  A61B3/113 ,  A61B5/12 ,  A61B5/4064 ,  A61B5/4076 ,  A61B5/7282

Abstract: An automated data acquisition, appraisal and analysis in noninvasive rapid screening of neuro-otologic condition using combination of subject's objective oculomotor, vestibular and reaction time analytic variables, comprises the steps of: establishing an oculomotor, vestibular and reaction time testing protocol for specific neuro-otologic condition which protocol included eye tracking aspects and which protocol obtains a combination of a subject's objective oculomotor, vestibular and reaction time analytic variables; coupling an eye tracker to subject; automatically establishing a region of interest for the eye tracker in which the region of interest is centered on the subject's pupils; conducting the oculomotor, vestibular and reaction time testing protocol using pre-programmed/automated voice instructions to the subject to obtain a combination of a subject's objective oculomotor, vestibular and reaction time analytic variables; and calculating and displaying a normalized composite test protocol score (0-1) on graphical progressive background.

公开(公告)号：US20240285223A1

公开(公告)日：2024-08-29

申请号：US18589974

申请日：2024-02-28

Applicant: NEW YORK UNIVERSITY

Inventor： Uzma Samadani

IPC: A61B5/00 ,  A61B3/00 ,  A61B3/08 ,  A61B3/103 ,  A61B3/107 ,  A61B3/113 ,  A61B3/12 ,  A61B3/14 ,  A61B3/16 ,  A61B5/03 ,  A61B5/11

CPC classification number: A61B5/4064 ,  A61B3/0091 ,  A61B3/085 ,  A61B3/103 ,  A61B3/107 ,  A61B3/113 ,  A61B3/12 ,  A61B3/14 ,  A61B3/16 ,  A61B5/031 ,  A61B5/1114 ,  A61B5/7278 ,  A61B5/7282

Abstract: A method for assessing neurological function in a subject includes a) prompting a user to follow a moving saccade-evoking stimulus on a display, b) tracking eye movement of the subject while the user follows the moving stimulus, c) collecting a first eye conjugacy data of the subject relating to the saccade-evoking stimulus, and d) comparing the first eye conjugacy data with a second eye conjugacy data, the second eye conjugacy data relating to an anti-saccade stimulus.

公开(公告)号：US12059263B2

公开(公告)日：2024-08-13

申请号：US18359363

申请日：2023-07-26

Applicant: International Business Machines Corporation

Inventor： Steven J. Holmes ,  Devendra K. Sadana ,  Stephen W. Bedell

IPC: A61B5/00

CPC classification number: A61B5/4064 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/046

Abstract: A method includes implanting an implantable biosensor within a subject where the implantable biosensor has an array of light sources and an array of light detectors, activating the array of light sources to direct light signals at a targeted tissue site in the subject, capturing, with the light detectors, the light signals reflected off the targeted site, calculating a roundtrip propagation time for each of the light signals and comparing the roundtrip propagation time for each of the light signals against previous calculated respective roundtrip propagation times to determine an occurrence of a change in the targeted tissue site.