DNA vaccine containing tumor-associated gene and cytokine gene and method of preparation the same
    13.
    发明申请
    DNA vaccine containing tumor-associated gene and cytokine gene and method of preparation the same 有权
    含有肿瘤相关基因和细胞因子基因的DNA疫苗及其制备方法

    公开(公告)号:US20050020520A1

    公开(公告)日:2005-01-27

    申请号:US10663048

    申请日:2003-09-16

    Abstract: The present invention discloses a DNA vaccine and its method of preparation, which employs DNA recombination technique to co-incorporate a fragment of tumor-associated gene and a fragment of cytokine gene into a vector. The administration of such DNA vaccine may enhance the immune response of the host through the co-expression of tumor-associated antigen and cytokine, and thereby achieve the therapeutic effect of inhibiting or retarding tumor growth.

    Abstract translation: 本发明公开了一种DNA疫苗及其制备方法,其采用DNA重组技术将肿瘤相关基因片段和细胞因子基因片段共同掺入载体中。 这种DNA疫苗的施用可以通过肿瘤相关抗原和细胞因子的共表达来增强宿主的免疫应答,从而达到抑制或延缓肿瘤生长的治疗效果。

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