公开(公告)号：US20110166199A1

公开(公告)日：2011-07-07

申请号：US12985684

申请日：2011-01-06

Applicant: Ming-Derg Lai ,  Shih-Shien Huang ,  Meng-Chi Yen ,  Chi-Chen Lin ,  Tzu-Yang Weng

Inventor： Ming-Derg Lai ,  Shih-Shien Huang ,  Meng-Chi Yen ,  Chi-Chen Lin ,  Tzu-Yang Weng

IPC: A61K31/713 ,  C07H21/02 ,  A61P35/00 ,  C12N15/63

CPC classification number: C12N15/113 ,  A61K31/713 ,  C12N2310/14 ,  C12N2310/531

Abstract: The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses. In addition, the present invention also disclosed that an RNAi compound targeted to Thrombospondin-1 gene can delay tumor progression.

Abstract translation: 本发明涉及用于抑制血小板反应蛋白-1表达的RNAi化合物和表达质粒，其包含选自凝血小儿反应蛋白-1基因的靶序列。 本发明还涉及包含RNAi化合物及其应用的药物组合物。 RNAi化合物可以降低血小板反应蛋白-1的表达，激活免疫应答。 此外，本发明还公开了靶向血小板反应蛋白-1基因的RNAi化合物可延缓肿瘤进展。

公开(公告)号：US20100067201A1

公开(公告)日：2010-03-18

申请号：US12558128

申请日：2009-09-11

Applicant: Yen-Liang CHEN ,  Ching-Hao YU ,  Meng-Hsuan SHIH ,  Wei-Chun CHIEN ,  Chien-Hsu HOU ,  Martijn BALLER ,  Jia-Rong LIN ,  Yung-Chie HUANG ,  Chi-Chen LIN ,  Chia-Ying LEE

Inventor： Yen-Liang CHEN ,  Ching-Hao YU ,  Meng-Hsuan SHIH ,  Wei-Chun CHIEN ,  Chien-Hsu HOU ,  Martijn BALLER ,  Jia-Rong LIN ,  Yung-Chie HUANG ,  Chi-Chen LIN ,  Chia-Ying LEE

IPC: H05K5/00

CPC classification number: G06F1/1683 ,  G06F1/1616 ,  G06F1/1637

Abstract: A flip electronic device includes a cover, a display module, a casing, a circuit board, and an electrical connection element. The casing is pivotally connected with the cover. The cover has a light-transparent portion. The display module is disposed at the cover. The circuit board is disposed in the casing. The electrical connection element is electrically connected with the display module and the circuit board. At least one portion of the electrical connection element is viewable through the light-transparent portion.

Abstract translation: 翻盖电子装置包括盖，显示模块，壳体，电路板和电连接元件。 外壳与盖枢轴连接。 盖具有透光部分。 显示模块设置在盖子上。 电路板设置在壳体中。 电连接元件与显示模块和电路板电连接。 电连接元件的至少一部分可透过透光部分观察。

公开(公告)号：US20100063758A1

公开(公告)日：2010-03-11

申请号：US12554688

申请日：2009-09-04

Applicant: Ching-Hao Yu ,  Meng-Hsuan Shih ,  Wei-Chun Chien ,  Chien-Hsu Hou ,  Martijn Baller ,  Jia-Rong Lin ,  Chia-Ying Lee ,  Yen-Liang Chen ,  Yung-Chie Huang ,  Chi-Chen Lin

Inventor： Ching-Hao Yu ,  Meng-Hsuan Shih ,  Wei-Chun Chien ,  Chien-Hsu Hou ,  Martijn Baller ,  Jia-Rong Lin ,  Chia-Ying Lee ,  Yen-Liang Chen ,  Yung-Chie Huang ,  Chi-Chen Lin

IPC: G01R31/36 ,  G01N27/416 ,  H01J1/62

CPC classification number: G06F1/181 ,  G01R31/3646

Abstract: An electronic apparatus with a power indication function is connected to an adapter. The electronic apparatus includes a host, a power jack, a rechargeable battery, a power indication element and a controller. The power jack is disposed on the host for connecting with the adapter. The rechargeable battery is disposed in the host and is electrically connected to the power jack. The power indication element has a switch disposed adjacent to the power jack and a power indicator disposed in the host. The controller is electrically connected to the rechargeable battery, the switch and the power indicator. When the switch turns on, the controller detects the remained power in the rechargeable battery and the remained power is indicated by the power indicator.

Abstract translation: 具有电源指示功能的电子设备连接到适配器。 电子设备包括主机，电源插座，可充电电池，电源指示元件和控制器。 电源插座设置在主机上，用于与适配器连接。 可再充电电池设置在主机中并电连接到电源插座。 电源指示元件具有邻近电源插座设置的开关和设置在主机中的电源指示器。 控制器电连接到可充电电池，开关和电源指示灯。 当开关打开时，控制器检测到可充电电池中的剩余电量，剩余电量由电源指示灯指示。

公开(公告)号：US07132407B2

公开(公告)日：2006-11-07

申请号：US10663048

申请日：2003-09-16

Applicant: Ming-Derg Lai ,  Chi-Chen Lin

Inventor： Ming-Derg Lai ,  Chi-Chen Lin

IPC: C12N15/26 ,  C12N15/12 ,  A61K31/711 ,  C12N15/861 ,  C12N15/867

CPC classification number: C07K14/55 ,  A61K39/0011 ,  A61K2039/53 ,  C07K14/71 ,  C07K2319/00

Abstract: The present invention discloses a DNA vaccine and the method of preparation preparing the same, which employs DNA recombination technique to co-incorporate a fragment of tumor-associated gene and a fragment of cytokine gene into a vector. The administration of such DNA vaccine can enhance the immune response of the host through the co-expression of tumor-associated protein and cytokine, and thereby achieve the therapeutic effect of inhibiting or retarding tumor growth.

Abstract translation: 本发明公开了一种DNA疫苗及其制备方法，采用DNA重组技术将肿瘤相关基因片段和细胞因子基因片段共同掺入载体。 这种DNA疫苗的施用可以通过肿瘤相关蛋白和细胞因子的共表达来增强宿主的免疫应答，从而达到抑制或延缓肿瘤生长的治疗效果。

公开(公告)号：US08377902B2

公开(公告)日：2013-02-19

申请号：US12985684

申请日：2011-01-06

Applicant: Ming-Derg Lai ,  Shih-Shien Huang ,  Meng-Chi Yen ,  Chi-Chen Lin ,  Tzu-Yang Weng

Inventor： Ming-Derg Lai ,  Shih-Shien Huang ,  Meng-Chi Yen ,  Chi-Chen Lin ,  Tzu-Yang Weng

IPC: A61K31/70 ,  C07H21/02 ,  C07H21/04 ,  C12Q1/68

CPC classification number: C12N15/113 ,  A61K31/713 ,  C12N2310/14 ,  C12N2310/531

Abstract: The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses. In addition, the present invention also disclosed that an RNAi compound targeted to Thrombospondin-1 gene can delay tumor progression.

Abstract translation: 本发明涉及用于抑制血小板反应蛋白-1表达的RNAi化合物和表达质粒，其包含选自凝血小儿反应蛋白-1基因的靶序列。 本发明还涉及包含RNAi化合物及其应用的药物组合物。 RNAi化合物可以降低血小板反应蛋白-1的表达，激活免疫应答。 此外，本发明还公开了靶向血小板反应蛋白-1基因的RNAi化合物可延缓肿瘤进展。

公开(公告)号：US20100046163A1

公开(公告)日：2010-02-25

申请号：US12543988

申请日：2009-08-19

Applicant: Ching-Hao YU ,  Martijn Baller ,  Yen-Liang Chen ,  Yung-Chie Huang ,  Meng-Hsuan Shih ,  Wei-Chun Chien ,  Chien-Hsu Hou ,  Chi-Chen Lin ,  Jia-Rong Lin ,  Chia-Ying Lee

Inventor： Ching-Hao YU ,  Martijn Baller ,  Yen-Liang Chen ,  Yung-Chie Huang ,  Meng-Hsuan Shih ,  Wei-Chun Chien ,  Chien-Hsu Hou ,  Chi-Chen Lin ,  Jia-Rong Lin ,  Chia-Ying Lee

IPC: H05K7/00

CPC classification number: G06F1/1662 ,  G06F1/1616

Abstract: A portable electronic device includes a casing, a covering layer, and a key. The casing has an opening. The covering layer covers at least one portion of the casing and covers the opening. The key is disposed at the opening and at least one portion of the key is embedded into the opening of the casing to allow one portion of the covering layer to be sandwiched between the key and the casing.

Abstract translation: 便携式电子设备包括壳体，覆盖层和键。 外壳有开口。 覆盖层覆盖壳体的至少一部分并覆盖开口。 键设置在开口处，并且钥匙的至少一部分嵌入到壳体的开口中，以允许覆盖层的一部分夹在键和壳体之间。

公开(公告)号：US20100051430A1

公开(公告)日：2010-03-04

申请号：US12548203

申请日：2009-08-26

Applicant: Martijn BALLER ,  Chi-Chen Lin ,  Yen-Liang Chen ,  Jia-Rong Lin ,  Chien-Hsu Hou ,  Meng-Hsuan Shih ,  Chia-Ying Lee ,  Wei-Chun Chien ,  Ching-Hao Yu ,  Yung-Chie Huang

Inventor： Martijn BALLER ,  Chi-Chen Lin ,  Yen-Liang Chen ,  Jia-Rong Lin ,  Chien-Hsu Hou ,  Meng-Hsuan Shih ,  Chia-Ying Lee ,  Wei-Chun Chien ,  Ching-Hao Yu ,  Yung-Chie Huang

IPC: H01H9/00 ,  H01H3/12

CPC classification number: H01H25/041 ,  H01H2209/002

Abstract: A button assembly is applied to a portable electronic device having a casing. The casing has an opening. The button assembly includes a button and a circuit board. The button is disposed at the opening and has a button body and a cloth-material layer. The cloth-material layer covers at least one portion of the button body and is exposed to a surface of the casing. The circuit board is disposed in the casing. The circuit board has a switch corresponding to the button body. A portable electronic device having the button assembly is also disclosed.

Abstract translation: 按钮组件被应用于具有外壳的便携式电子设备。 外壳有开口。 按钮组件包括按钮和电路板。 按钮设置在开口处，并具有按钮体和布料层。 布料层覆盖按钮体的至少一部分并暴露于外壳的表面。 电路板设置在壳体中。 电路板具有对应于按钮体的开关。 还公开了具有按钮组件的便携式电子设备。

公开(公告)号：US06343644B1

公开(公告)日：2002-02-05

申请号：US09521920

申请日：2000-03-09

Applicant: Horng-Chieh Huang ,  Kun-Lung Tsai ,  Ching-Yuan Lin ,  Chi-Chen Lin

Inventor： Horng-Chieh Huang ,  Kun-Lung Tsai ,  Ching-Yuan Lin ,  Chi-Chen Lin

IPC: F28D1102

CPC classification number: F16C37/00 ,  Y10S165/135

Abstract: A hollow screw cooling device, which has a set of apertures provided on an oil-proof base on the driven end of the hollow screw. By having fixing screws go through the apertures and the through holes on the bearing press board and fixed on the bearing base, the oil-proof base can be fixed on the outer side of the bearing press board. By directly taking off fixing screws, the oil-proof base can be directly taken off the bearing base when maintaining or replacing the seal without disassembling the components such as the bearing and bearing device.

Abstract translation: 中空螺杆冷却装置，其具有设置在中空螺杆的从动端上的防油底座上的一组孔。 通过固定螺丝穿过轴承压板上的孔和通孔并固定在轴承座上，防油底座可以固定在轴承压板的外侧。 通过直接取下固定螺丝，在不拆卸轴承和轴承装置等部件的情况下，可以在保持或更换密封件时，将防油底座直接从轴承座取下。

公开(公告)号：US08072748B2

公开(公告)日：2011-12-06

申请号：US12545419

申请日：2009-08-21

Applicant: Martijn Baller ,  Meng-Hsuan Shih ,  Chi-Chen Lin ,  Chien-Hsu Hou ,  Yen-Liang Chen ,  Chia-Ying Lee ,  Wei-Chun Chien ,  Yung-Chie Huang ,  Jia-Rong Lin ,  Ching-Hao Yu

Inventor： Martijn Baller ,  Meng-Hsuan Shih ,  Chi-Chen Lin ,  Chien-Hsu Hou ,  Yen-Liang Chen ,  Chia-Ying Lee ,  Wei-Chun Chien ,  Yung-Chie Huang ,  Jia-Rong Lin ,  Ching-Hao Yu

IPC: G06F1/16

CPC classification number: G06F1/1688 ,  G06F1/1616

Abstract: A portable electronic device includes a casing, a key, a loudspeaker, a soft insulating material, and an actuating unit. The key is disposed at the casing. The loudspeaker is embedded into the casing flatly. The soft insulating material covers the casing and the loudspeaker. The actuating unit is coupled to the key and the loudspeaker, and it actuates the loudspeaker to protrude from the casing in response to an actuation of the key.

Abstract translation: 便携式电子设备包括壳体，键，扬声器，软绝缘材料和致动单元。 钥匙设在外壳上。 扬声器平坦地嵌入到外壳中。 软绝缘材料覆盖外壳和扬声器。 致动单元耦合到钥匙和扬声器，并且响应于钥匙的致动而致动扬声器从壳体突出。

公开(公告)号：US20110011270A1

公开(公告)日：2011-01-20

申请号：US12837446

申请日：2010-07-15

Applicant: Meng-Hsuan Shih ,  Chi-Han Wang ,  Yu-Chi Chen ,  Chi-Chen Lin ,  Chia-En Lu

Inventor： Meng-Hsuan Shih ,  Chi-Han Wang ,  Yu-Chi Chen ,  Chi-Chen Lin ,  Chia-En Lu

IPC: A47J31/44

CPC classification number: A47G19/14 ,  A47G19/16 ,  B65D85/8085

Abstract: A disposable tea set includes a teapot and a teacup. The teapot is folded from a first sheet, and the first sheet includes a pot bottom portion, a plurality of pot wall portions, a plurality of folding portions, and a pot lid portion. The pot wall portions surround and are connected with the pot bottom portion, and the pot wall portions and the pot bottom portion form seamless connections. The folding portions are connected with the pot wall portions which are adjacent to each other, respectively, and they are folded to make the pot wall portions to form a pot body. One of the folding portions extends to outside of the pot body to form a spout. The pot lid portion is connected with one of the pot wall portions. The teacup is folded from a second sheet and is accommodated in the teapot.

Abstract translation: 一次性茶具包括茶壶和茶杯。 茶壶从第一片折叠起来，第一片包括罐底部，多个锅壁部，多个折叠部和壶盖部。 锅壁部分包围并与罐底部分连接，并且锅壁部分和罐底部分形成无缝连接。 折叠部分分别与彼此相邻的锅壁部分连接，并且它们被折叠以使锅壁部分形成锅体。 一个折叠部分延伸到锅体的外部以形成喷口。 锅盖部与锅壁部之一连接。 茶杯从第二片折叠并容纳在茶壶中。