公开(公告)号：US20240010969A1

公开(公告)日：2024-01-11

申请号：US18456333

申请日：2023-08-25

Applicant: Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences ,  Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences

Inventor： Xueli Zhang ,  Luqi Huang ,  Zhubo Dai ,  Dong Wang ,  Lili Zhang ,  Juan Guo ,  Yi Liu

IPC: C12N1/18 ,  C12N9/88 ,  C12N9/10 ,  C12N15/63 ,  C12P5/00

CPC classification number: C12N1/185 ,  C12N9/88 ,  C12N9/1085 ,  C12N15/63 ,  C12P5/007 ,  C12Y402/03023 ,  C12Y205/0101

Abstract: Provided is a recombinant yeast expressing germacrene A synthetase or a fusion protein thereof, wherein the fusion protein is germacrene A synthetase and farnesyl pyrophosphate synthase. The recombinant yeast improves the yield of germacrene A, and is suitable for the industrialized production of β-elemene and/or germacrene A.