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    Dentifrice compositions comprising a stable low water, phase comprising polyphosphate and ionic active ingredients
    11.
    发明授权
    Dentifrice compositions comprising a stable low water, phase comprising polyphosphate and ionic active ingredients 有权
    包含稳定的低水，含有多磷酸盐和离子活性成分的相的牙粉组合物

    公开(公告)号：US06696045B2

    公开(公告)日：2004-02-24

    申请号：US10302031

    申请日：2002-11-22

    Applicant: Jiang Yue ,  Long Zhu ,  Li Chen ,  Ying Cheng ,  Tao Xu ,  Andrew Damian Weller ,  Ying Wang

    Inventor： Jiang Yue ,  Long Zhu ,  Li Chen ,  Ying Cheng ,  Tao Xu ,  Andrew Damian Weller ,  Ying Wang

    IPC: A61K716

    CPC classification number: A61Q11/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8147 ,  A61K8/90

    Abstract: Disclosed are dentifrice compositions comprising in a single phase: (a) from about 0.1% to about 30% of one or more linear polyphosphates having an average chain length of about 4 or more; (b) an ionic active ingredient selected from the group consisting of a fluoride ion source, a stannous ion source, a zinc ion source, a copper ion source and mixtures thereof, wherein the ionic active ingredient is present as a solid dispersion in the composition and delivers and effective amount of ionic active when solubilized; (c) a binder system comprised of (i) from about 0.05% to about 3% of a thickening agent selected from the group consisting of polysaccharides, carbomers, poloxamers, modified celluloses, and mixtures thereof; and (ii) from about 0.1% to about 70% of at least one humectant; wherein the dentifrice composition has a total water content of less than about 10%. Further disclosed are methods for stabilizing dentifrice compositions by providing such a binder system.

    Abstract translation: 公开了含有单相的洁齿剂组合物：（a）约0.1％至约30％的一种或多种平均链长为约4或更大的线性多磷酸盐; （b）选自氟离子源，亚锡离子源，锌离子源，铜离子源及其混合物的离子活性成分，其中离子活性成分作为固体分散体存在于组合物中 并在溶解时提供有效量的离子活性物质; （c）粘合剂体系，其包含（i）约0.05％至约3％的选自多糖，卡波姆，泊洛沙姆，改性纤维素及其混合物的增稠剂; 和（ii）约0.1％至约70％的至少一种湿润剂; 其中洁牙剂组合物的总含水量小于约10％。 进一步公开的是通过提供这种粘合剂体系来稳定洁齿剂组合物的方法。

    Systems comprising organosiloxane resins for delivering oral care substances and for prolonging such delivery
    12.
    发明授权
    Systems comprising organosiloxane resins for delivering oral care substances and for prolonging such delivery 失效
    系统包括用于递送口腔护理物质并延长这种递送的有机硅氧烷树脂

    公开(公告)号：US06692727B1

    公开(公告)日：2004-02-17

    申请号：US10019031

    申请日：2002-03-20

    Applicant: Jiang Yue ,  Sekhar Mitra

    Inventor： Jiang Yue ,  Sekhar Mitra

    IPC: A61K716

    CPC classification number: A61K8/0208 ,  A61K6/0017 ,  A61K8/26 ,  A61K8/31 ,  A61K8/34 ,  A61K8/891 ,  A61Q11/00 ,  C08L83/04

    Abstract: Disclosed is a system for delivering an oral care substance to the oral cavity comprising: (a) a delivery composition comprised of: (i) an organosiloxane resin; (ii) a volatile carrier capable of solubilizing the organosiloxane resin; (iii) a rheology modifier; and (iv) at least one oral care substance; and (b) a protective composition comprised of: (i) an organosiloxane resin; and (ii) a volatile carrier capable of solubilizing the organosiloxane resin. Further disclosed is a system for delivering an oral care substance to the oral cavity comprising: (a) a delivery composition comprised of: (i) an organosiloxane resin; (ii) a fluid diorganopolysiloxane-based polymer; (iii) a volatile carrier capable of solubilizing the organosiloxane resin and the fluid diorganopolysiloxane-based polymer; (iv) a rheology modifier; and (v) at least one oral care substance; and (b) a protective composition comprised of: (i) an organosiloxane resin; and (ii) a volatile carrier capable of solubilizing the organosiloxane resin. The protective composition may further comprise a fluid diorganopolysiloxane-based polymer and/or a rheology modifier. Still further disclosed is a method of using these systems.

    Abstract translation: 公开了一种用于将口腔护理物质递送到口腔的系统，包括：（a）递送组合物，其包含：（i）有机硅氧烷树脂; （ii）能够溶解有机硅氧烷树脂的挥发性载体; （iii）流变改性剂; 和（iv）至少一种口腔护理物质; 和（b）保护性组合物，其包含：（i）有机硅氧烷树脂; 和（ii）能溶解有机硅氧烷树脂的挥发性载体。 还公开了一种用于将口腔护理物质递送到口腔的系统，包括：（a）递送组合物，其包含：（i）有机硅氧烷树脂; （ii）流体二有机聚硅氧烷基聚合物; （iii）能够溶解有机硅氧烷树脂和流体二有机聚硅氧烷基聚合物的挥发性载体; （iv）流变改性剂; 和（v）至少一种口腔护理物质; 和（b）保护性组合物，其包含：（i）有机硅氧烷树脂; 和（ii）能溶解有机硅氧烷树脂的挥发性载体。 保护性组合物还可以包含流体二有机聚硅氧烷基聚合物和/或流变改性剂。 还公开了使用这些系统的方法。

    Proton concentration sensor/modulator for sulfonated and hydroxylated polyaniline electrodes
    13.
    发明授权
    Proton concentration sensor/modulator for sulfonated and hydroxylated polyaniline electrodes 失效
    用于磺化和羟基化聚苯胺电极的质子浓度传感器/调制器

    公开(公告)号：US5250163A

    公开(公告)日：1993-10-05

    申请号：US800363

    申请日：1991-11-27

    Applicant: Arthur J. Epstein ,  Jiang Yue ,  David R. Burley

    Inventor： Arthur J. Epstein ,  Jiang Yue ,  David R. Burley

    IPC: G01N27/30 ,  G01N27/26

    CPC classification number: G01N27/4167

    Abstract: Broadly, the present invention takes advantage of the ability of self-protonated sulfonated polyaniline (SPAN) to sense and/or modulate pH of a medium in the vicinity of a SPAN electrode. Accordingly, one aspect of the present invention is directed to a method for sensing pH of a medium in the vicinity of a sensing electrode wherein a SPAN electrode and a counter-electrode are placed in a medium and an indicia of said SAN correlative with the pH of said medium is monitored. As another aspect of the present invention, the pH of a medium in the vicinity of a sensing electrode is modulated by placing a SPAN electrode in the medium and applying a voltage to the electrode to controllably emit or absorb protons from said electrode to modulate the pH of the medium in the vicinity of the electrode. As a further aspect of the present invention, the activity/state of a biosensor/catalyst is sensed for the activity/state correlative with pH. As a further aspect of the present invention, the activity/state of a biosensor/catalyst, where the activity/state is correlative with pH, is controlled by associating the biosensor/catalyst with a SPAN electrode in contact with a medium containing said biosensor/catalyst, and applying a voltage to said electrode to controllably emit or absorb protons from said electrode to control the activity/state of said biosensor/catalyst.

    Abstract translation: 广泛地，本发明利用自质子化磺化聚苯胺（SPAN）在SPAN电极附近感测和/或调节介质的pH的能力。 因此，本发明的一个方面涉及一种用于感测感测电极附近的介质的pH的方法，其中将SPAN电极和对电极放置在介质中，并且所述SAN的标记与pH相关 的所述介质被监测。 作为本发明的另一方面，通过将SPAN电极放置在介质中并向电极施加电压来调制感测电极附近的介质的pH，以可控制地从所述电极发射或吸收质子以调节pH 介质在电极附近。 作为本发明的另一方面，检测与pH相关的活性/状态的生物传感器/催化剂的活性/状态。 作为本发明的另一方面，活性/状态与pH相关的生物传感器/催化剂的活性/状态通过将生物传感器/催化剂与含有所述生物传感器/催化剂的介质接触的SPAN电极相关联来控制， 催化剂，并向所述电极施加电压以可控制地从所述电极发射或吸收质子，以控制所述生物传感器/催化剂的活性/状态。

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