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    Cushioned orthotic
    12.
    发明授权
    Cushioned orthotic 有权
    缓冲矫形器

    公开(公告)号：US08800169B2

    公开(公告)日：2014-08-12

    申请号：US13969949

    申请日：2013-08-19

    Applicant: MSD Consumer Care, Inc.

    Inventor： Harold A. Howlett ,  Bin Xia ,  Philip C. Yang

    IPC: A43B13/38

    CPC classification number: A43B13/386 ,  A43B7/142 ,  A43B7/144 ,  A43B7/223 ,  A43B13/38 ,  A43B13/40 ,  A43B17/006 ,  A43B17/023 ,  A43D1/02 ,  A43D999/00 ,  A61B5/1036 ,  A61B5/1074 ,  A61B5/411 ,  A61B5/6892 ,  A61B2562/0247 ,  A61B2562/046 ,  A61F5/14 ,  G06Q30/06

    Abstract: An orthotic is disclosed. The orthotic may include a cushioning layer configured to extend from at least the metatarsal region to the proximal heel region, the cushioning layer having a heel region with a protruding heel piece integrally molded as part of the cushioning layer. The orthotic may also include an outer shell layer fixedly coupled to the cushioning layer, the outer shell layer extending longitudinally from at least the medial cuneiform-first metatarsal joint region to the calcaneus bone region of the user, the outer shell layer configured to receive the protruding heel piece.

    Abstract translation: 公开了一种矫形器。 矫形器可以包括构造成从至少跖骨区域延伸到近侧跟部区域的缓冲层，缓冲层具有跟部区域，其具有作为缓冲层的一部分整体模制的突出的后跟件。 矫形器还可以包括固定地联接到缓冲层的外壳层，外壳层从至少内侧楔形第一跖骨关节区域纵向延伸到使用者的跟骨骨区域，外壳层被构造成接收 突出的脚跟片。

    CUSHIONING DEVICE
    13.
    发明申请
    CUSHIONING DEVICE 审中-公开
    冲洗装置

    公开(公告)号：US20140209229A1

    公开(公告)日：2014-07-31

    申请号：US14163377

    申请日：2014-01-24

    Applicant: MSD Consumer Care, Inc.

    Inventor： Philip C. Yang

    IPC: A43B19/00

    CPC classification number: A43B19/00 ,  A43B17/006 ,  A43B17/02 ,  Y10T156/10 ,  Y10T428/1452 ,  Y10T428/2495 ,  Y10T428/266 ,  Y10T428/269 ,  Y10T428/2848

    Abstract: A cushioning device including a layer of styrenic based gel material having top and bottom surfaces, a first layer including: i. layer of maleic anhydride and ii. layer of thermoplastic polyurethane, wherein the first layer has a surface bonded to the top surface of the layer of styrenic based gel material, the second layer has a surface bonded to the bottom of the layer of styrenic based gel material and wherein a pressure sensitive adhesive coating is disposed on at least one of the first and second layers opposite to the layer of styrenic based gel material.

    Abstract translation: 一种缓冲装置，包括具有顶表面和底表面的苯乙烯基凝胶材料层，第一层包括：i。 层马来酸酐和ii。 层，其中所述第一层具有粘合到所述苯乙烯类凝胶材料层的顶表面的表面，所述第二层具有结合到所述苯乙烯类凝胶材料层的底部的表面，并且其中压敏粘合剂 所述涂层设置在所述第一层和所述第二层中与所述苯乙烯类凝胶材料层相对的至少一个上。

    FOOTCARE PRODUCT DISPENSING KIOSK
    14.
    发明申请
    FOOTCARE PRODUCT DISPENSING KIOSK 审中-公开
    FOOTCARE产品分配KIOSK

    公开(公告)号：US20140107968A1

    公开(公告)日：2014-04-17

    申请号：US14134115

    申请日：2013-12-19

    Applicant: MSD Consumer Care, Inc.

    Inventor： Bin Xia ,  Harold A. Howlett ,  Charles E. Lundy

    IPC: A61B5/103

    CPC classification number: G06Q30/0631 ,  A43B7/24 ,  A43D1/02 ,  A43D1/022 ,  A43D1/08 ,  A61B5/1036 ,  G06Q20/20

    Abstract: A kiosk apparatus that may select for a person a recommended footcare product based on pressure measurements collected from pressures sensors or calculated biomechanical data estimates. Pressure measurements and calculated biomechanical data estimates may be used to determine if a foot is unshod on the pressure sensor and also group a person into a classified subgroup. The pressure measurement and calculated biomechanical data estimates may also be used to select a recommended footcare product.

    Abstract translation: 可以根据从压力传感器收集的压力测量值或计算出的生物力学数据估计值，为个人选择推荐的足部护理产品的信息亭装置。 可以使用压力测量和计算的生物力学数据估计来确定脚是否在压力传感器上是否正确，并且还将一个人分组成分类的子组。 压力测量和计算的生物力学数据估计也可用于选择推荐的足部护理产品。

    PHENYLEPHRINE PHARMACEUTICAL FORMULATIONS AND COMPOSITIONS FOR COLONIC ABOSORPTION
    19.
    发明申请
    PHENYLEPHRINE PHARMACEUTICAL FORMULATIONS AND COMPOSITIONS FOR COLONIC ABOSORPTION 审中-公开
    苯并噻唑类药物制剂及其组合物

    公开(公告)号：US20150290147A1

    公开(公告)日：2015-10-15

    申请号：US14571890

    申请日：2014-12-16

    Applicant: MSD Consumer Care, Inc.

    Inventor： David Monteith ,  John O'Mullane ,  Robert T. Nowak ,  Jiansheng Wan ,  Mohammed A. Kabir ,  Joseph P. Reo ,  Malaz A. Abutarif ,  Glenn E. Fritz

    IPC: A61K31/137 ,  A61K47/12 ,  A61K31/4545 ,  A61K47/38 ,  A61K9/50 ,  A61K9/16

    CPC classification number: A61K31/137 ,  A61K9/167 ,  A61K9/2054 ,  A61K9/209 ,  A61K9/5026 ,  A61K9/5042 ,  A61K31/4545 ,  A61K47/12 ,  A61K47/38

    Abstract: The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layer(s). The pharmaceutical composition can further comprise one or more additional therapeutically active agents selected from one or more of the group consisting of antihistamines, analgesics, anti-pyretics, and non-steroidal anti-inflammatory agents. The invention also discloses methods of administering phenylephrine via the colon, thereby increasing the bioavailable amount of therapeutically active unconjugated phenylephrine relative to the total phenylephrine in the plasma.

    Abstract translation: 本发明公开了一种药物组合物，其包含去氧肾上腺素或其药学上可接受的盐和用于口服给药的可溶性层，其中所述组合物通过在结肠中的吸收递送苯肾上腺素或其药学上可接受的盐。 药物组合物包含包含去氧肾上腺素或其药学上可接受的盐的核心和可溶性层，其处于时间依赖性，依赖于pH或结肠特异性的酶依赖性可溶解层，其降解以暴露核心以释放出去氧肾上腺素 结肠。 在一个优选实施例中，可侵蚀层包裹芯。 所述组合物任选地还包含可腐蚀层或其它附加层中的去氧肾上腺素。 药物组合物还可以包含一种或多种另外的治疗活性剂，其选自抗组胺剂，止痛剂，抗热解剂和非甾体抗炎剂中的一种或多种。 本发明还公开了通过结肠施用苯肾上腺素的方法，从而相对于血浆中的总去氧肾上腺素增加了治疗活性的非共轭去氧肾上腺素的生物可利用量。

    Footcare product dispensing kiosk
    20.
    发明授权
    Footcare product dispensing kiosk 有权
    足部护理产品点胶亭

    公开(公告)号：US09038482B2

    公开(公告)日：2015-05-26

    申请号：US14052297

    申请日：2013-10-11

    Applicant: MSD Consumer Care, Inc.

    Inventor： Bin Xia ,  Harold A. Howlett ,  Charles E. Lundy

    IPC: G01D7/00 ,  A61B5/103 ,  A43D1/02 ,  A43D1/08

    CPC classification number: G06Q30/0631 ,  A43B7/24 ,  A43D1/02 ,  A43D1/022 ,  A43D1/08 ,  A61B5/1036 ,  G06Q20/20

    Abstract: A kiosk apparatus that may select for a person a recommended footcare product based on pressure measurements collected from pressures sensors or calculated biomechanical data estimates. Pressure measurements and calculated biomechanical data estimates may be used to determine if a foot is unshod on the pressure sensor and also group a person into a classified subgroup. The pressure measurement and calculated biomechanical data estimates may also be used to select a recommended footcare product.

    Abstract translation: 可以根据从压力传感器收集的压力测量值或计算出的生物力学数据估计值，为个人选择推荐的足部护理产品的信息亭装置。 可以使用压力测量和计算的生物力学数据估计来确定脚是否在压力传感器上是否正确，并且还将一个人分组成分类的子组。 压力测量和计算的生物力学数据估计也可用于选择推荐的足部护理产品。

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