公开(公告)号：US6086103A

公开(公告)日：2000-07-11

申请号：US853350

申请日：1997-05-08

申请人： Masami Fukagawa ,  Masayuki Sano ,  Shingo Nagamine ,  Hideya Miyashiro

发明人： Masami Fukagawa ,  Masayuki Sano ,  Shingo Nagamine ,  Hideya Miyashiro

IPC分类号： B60G7/00 ,  B60K15/03 ,  B60K15/07 ,  B60K15/10 ,  B62D25/08 ,  F02M37/00 ,  B60P3/22

CPC分类号： B60K15/07 ,  B60K2015/0638

摘要： A structure arranged under a floor panel for mounting a tank to be charged with a pressurized-fuel such as natural gas and liquefied petroleum gas in a motorcar of front engine --front drive type is provided. The pressurized-fuel tank installation structure in a motorcar includes a chassis frame formed in a frame-shape for surrounding and supporting the pressurized-fuel tank and attached to a lower surface of the car-body from underside of the floor panel, the pressurized-fuel tank being positioned in the frame-shape and fitted to the chassis frame integrally; a rear wheel suspension provided on the chassis frame; and a pipe arranged along a lower surface of the floor panel for connecting the pressurized-fuel tank and an internal combustion engine with each other.

摘要翻译： 提供了一种布置在地板面板下方的结构，用于在前发动机前驱动型的汽车中安装用于装载诸如天然气和液化石油气之类的加压燃料的罐。 汽车中的加压燃料箱安装结构包括框架形状的框架框架，用于围绕和支撑加压燃料箱，并从底板的下侧附接到车体的下表面， 燃料箱定位在框架形状并整体安装在底盘框架上; 设置在底架上的后轮悬架; 以及沿着地板面板的下表面布置的用于将加压燃料箱和内燃机彼此连接的管。

公开(公告)号：US5992885A

公开(公告)日：1999-11-30

申请号：US855723

申请日：1997-05-08

申请人： Masami Fukagawa ,  Masayuki Sano

发明人： Masami Fukagawa ,  Masayuki Sano

IPC分类号： B60K15/03 ,  B60G3/20 ,  B60K15/063 ,  B60K15/07 ,  B62D43/04 ,  F02M37/00

CPC分类号： B60K15/07 ,  B60G3/202 ,  B62D43/04 ,  B60G2200/182 ,  B60G2202/312 ,  B60G2204/129 ,  B60G2204/143 ,  B60G2204/15 ,  B60G2206/60 ,  B60K2015/0638

摘要： A fuel cylinder mounting structure of a motorcar wherein a fuel cylinder can be attached together with suspensions and a spare tire easily so that productivity is improved, the vehicle can be made small and light, and reduction of cost can be attempted is provided. The fuel cylinder mounting structure comprises a fuel cylinder for storing compressed fuel gas; a chassis frame having a rectangular frame-like shape, supporting the fuel cylinder and attached to a car-body frame from the bottom; a protection plate fixed to the chassis frame for covering the fuel cylinder from the bottom; suspensions attached to both sides of the chassis frame and modularized with the chassis frame; and a spare tire rack attached under a rear car-body and supporting a spare tire laid down so as to be hung in rear of the protection plate.

摘要翻译： 一种汽车的燃料缸安装结构，其中燃料缸可以容易地与悬架和备用轮子一起安装，从而提高生产率，从而可以使车辆小型化，轻量化，降低成本。 燃料缸安装结构包括用于储存压缩燃料气体的燃料缸; 具有矩形框状的底盘框架，支撑燃料缸并从底部附接到车身框架; 保护板，其固定到底架上，用于从底部覆盖燃料缸; 悬挂在底盘框架的两侧并与底盘框架模块化; 以及备用轮胎架，其安装在后车体的下方，并且支撑放置的悬挂在保护板后部的备用轮胎。

公开(公告)号：US20120214240A1

公开(公告)日：2012-08-23

申请号：US13292953

申请日：2011-11-09

申请人： Mahito NAKANISHI ,  Ken NISHIMURA ,  Masayuki SANO ,  Manami OHTAKA

发明人： Mahito NAKANISHI ,  Ken NISHIMURA ,  Masayuki SANO ,  Manami OHTAKA

IPC分类号： C12N15/86 ,  C12N5/0789 ,  C07H21/02 ,  C12N7/01

CPC分类号： C12N15/86 ,  C12N5/0696 ,  C12N15/1131 ,  C12N15/8775 ,  C12N15/8776 ,  C12N2310/14 ,  C12N2501/602 ,  C12N2501/603 ,  C12N2501/604 ,  C12N2501/606 ,  C12N2510/00 ,  C12N2760/18843

摘要： A reprogramming gene-loaded Sendai viral vector comprising Sendai virus genes and reprogramming genes, wherein the Sendai virus genes include an NP gene, P/C gene, M gene, F gene, HN gene and L gene, wherein each of the M gene, the F gene and the FIN gene is from a Sendai virus strain Cl.151-derived gene and wherein at least one of the M gene, the F gene and the HN gene is functionally deleted and the L gene encodes the amino-acid sequence of the L protein in which the amino-acid residue at position 1618 is valine and a method of producing the same.

摘要翻译： 包含仙台病毒基因和重编程基因的重编程基因载体仙台病毒载体，其中仙台病毒基因包括NP基因，P / C基因，M基因，F基因，HN基因和L基因，其中M基因， F基因和FIN基因来自仙台病毒株Cl.151衍生的基因，其中M基因，F基因和HN基因中的至少一个在功能上被缺失，并且L基因编码氨基酸序列 1618位氨基酸残基为缬氨酸的L蛋白及其制备方法。

公开(公告)号：US20100311171A1

公开(公告)日：2010-12-09

申请号：US12792580

申请日：2010-06-02

申请人： Mahito NAKANISHI ,  Ken NISHIMURA ,  Manami OHTAKA ,  Masayuki SANO

发明人： Mahito NAKANISHI ,  Ken NISHIMURA ,  Manami OHTAKA ,  Masayuki SANO

IPC分类号： C12N15/86 ,  C12N15/63 ,  C12N5/10 ,  C07H21/02 ,  C12N7/01

CPC分类号： C12N5/0696 ,  C12N15/1131 ,  C12N15/86 ,  C12N15/8775 ,  C12N15/8776 ,  C12N2310/14 ,  C12N2501/602 ,  C12N2501/603 ,  C12N2501/604 ,  C12N2501/606 ,  C12N2510/00 ,  C12N2760/18843

摘要： Stem cell reprogramming genes cloned into a single sustained expression-type Sendai viral vector are shown to reprogram differentiated somatic cells into induced pluripotent stem (iPS) cells without integration of vector sequences into the host cell's genome. The genes are transduced into normal differentiated somatic cells via infection with recombinant Sendai virus. After expression of the reprogramming genes and subsequent induction of pluripotency, the vector genome RNA including the reprogramming genes is removed from the cell to establish an iPS cell that is genetically identical to the parent somatic differentiated cell thus reducing the risk of tumorigenic transformation caused by random integration of vector sequences into the host genome. The method promises to provide safe, autologous iPS cells that can be used for human cell replacement and regeneration therapeutic applications.

摘要翻译： 克隆到单一持续表达型仙台病毒载体中的干细胞重编程基因显示将分化的体细胞重编程为诱导多能干细胞（iPS）细胞，而不将载体序列整合到宿主细胞的基因组中。 通过感染重组仙台病毒将基因转导入正常分化的体细胞。 在重编程基因表达和随后的多能性诱导之后，从细胞中除去包括重编程基因的载体基因组RNA以建立与亲本体细胞分化细胞遗传相同的iPS细胞，从而降低由随机引起的致瘤转化的风险 将载体序列整合到宿主基因组中。 该方法有望提供可用于人类细胞替代和再生治疗应用的安全的自体iPS细胞。