公开(公告)号：US20110110573A1

公开(公告)日：2011-05-12

申请号：US13000030

申请日：2009-06-23

Applicant: Jens Wiegert ,  Matthias Bertram

Inventor： Jens Wiegert ,  Matthias Bertram

IPC: G06K9/00 ,  G06K9/34

CPC classification number: G06T11/005 ,  A61B6/032 ,  A61B6/542

Abstract: The present invention relates to an image generation device for generating an image from measured data, wherein image quality is optimized for a region of interest and to an imaging system comprising this image generation device. The image generation device comprises a noise determination unit for determining a distribution of noise in a projection domain of the region of interest, and a dose control unit (32) for determining a dose profile for a radiation source (2) of said image generation device based on said determined distribution of noise by using a noise propagation algorithm. Thereby, signal-to-noise ratio of a reconstructed volume can be improved and is not sensitively dependent on a selected region of interest.

Abstract translation: 本发明涉及一种用于根据测量数据产生图像的图像产生装置，其中对于感兴趣的区域和包括该图像生成装置的成像系统优化图像质量。 该图像生成装置包括用于确定感兴趣区域的投影域中的噪声分布的噪声确定单元，以及用于确定所述图像生成装置的辐射源（2）的剂量分布的剂量控制单元（32） 基于所述确定的噪声分布，使用噪声传播算法。 因此，可以改善重建体积的信噪比并且不敏感地依赖于所选择的感兴趣区域。

公开(公告)号：US20110060566A1

公开(公告)日：2011-03-10

申请号：US12991708

申请日：2009-05-13

Applicant: Matthias Bertram ,  Jens Wiegert ,  Steffen Gunther Hohmann

Inventor： Matthias Bertram ,  Jens Wiegert ,  Steffen Gunther Hohmann

IPC: G06F17/10

CPC classification number: G06T11/005

Abstract: A method and apparatus of image reconstruction correcting for photon scatter is provided. A direct physical measurement of scattered photons is used in conjunction with a physical model of the photon scattering process to make the corrections.

Abstract translation: 提供了一种用于光子散射的图像重建校正方法和装置。 散射光子的直接物理测量与光子散射过程的物理模型结合使用以进行校正。

公开(公告)号：US20100119139A1

公开(公告)日：2010-05-13

申请号：US12625600

申请日：2009-11-25

Applicant: Matthias Bertram ,  Jens Wiegert ,  Steffen G. Wiesner

Inventor： Matthias Bertram ,  Jens Wiegert ,  Steffen G. Wiesner

IPC: G06K9/62

CPC classification number: G06T11/005

Abstract: A method includes generating a plurality of scatter distributions based on geometric models having different object to detector distances, determining an imaged object to detector distance, and identifying a scatter distribution of the plurality of scatter distributions having a object to detector distance that corresponds to the imaged object to detector distance. The method also includes employing the identified scatter distribution to scatter correct projection data corresponding to the imaged object. Another method includes generating an estimate of wedge scatter by propagating a predetermined wedge scatter profile through an intermediate reconstruction of an object; and employing the estimate to wedge scatter correct the projection data.

Abstract translation: 一种方法包括基于具有不同对象与检测器距离的几何模型来生成多个散射分布，将成像对象确定为检测器距离，以及识别具有对象的多个散射分布的散射分布与检测器距离对应于被成像 对象到检测器距离。 该方法还包括使用所识别的散布分布散布对应于成像对象的正确投影数据。 另一种方法包括通过传播预定的楔形散射剖面通过对象的中间重建来产生楔散射的估计; 并使用估计来楔形散射校正投影数据。

公开(公告)号：US09659365B2

公开(公告)日：2017-05-23

申请号：US13640574

申请日：2011-04-05

Applicant: Alexandra Groth ,  Qi Sun ,  Matthias Bertram

Inventor： Alexandra Groth ,  Qi Sun ,  Matthias Bertram

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06T7/0012 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/20108 ,  G06T2207/30104

Abstract: A flow pattern in a tube system is calculated from acquired image data. From the flow pattern virtual image data are generated and compared with the acquired data in order to determine a quality measure for the usability of the generated flow pattern at characteristic locations.

公开(公告)号：US09014780B2

公开(公告)日：2015-04-21

申请号：US12942269

申请日：2010-11-09

Applicant: Herfried Wieczorek ,  Matthias Bertram

Inventor： Herfried Wieczorek ,  Matthias Bertram

IPC: A61B5/05 ,  A61B6/03 ,  A61B6/00 ,  A61B19/00 ,  A61B10/02 ,  G01R33/48

CPC classification number: A61B6/032 ,  A61B6/037 ,  A61B6/4233 ,  A61B6/4417 ,  A61B6/487 ,  A61B6/5235 ,  A61B6/5264 ,  A61B10/0233 ,  A61B34/10 ,  A61B2034/107 ,  A61B2034/2065 ,  A61B2090/364 ,  G01R33/481

Abstract: When performing image-guided biopsy of an anatomical structure in a patient, a target anatomical patient region containing biopsy target is imaged using both SPECT and XCT concurrently. 3D SPECT and XCT image data is fused to generate a fused 3D reference image that is overlaid on 2D patient image(s) generated during the biopsy procedure to generate an overlay image. The overlay image also includes a planned path or trajectory for a biopsy instrument. The 2D patient images are generated using SPECT and/or XCT, and are updated periodically to show biopsy instrument position and progress.

Abstract translation: 当在患者中进行解剖结构的图像引导活组织检查时，使用SPECT和XCT同时成像含有活组织检查靶的目标解剖学患者区域。 融合3D SPECT和XCT图像数据以产生融合的3D参考图像，其覆盖在活检过程中产生的2D患者图像上以产生覆盖图像。 覆盖图像还包括活检仪器的计划路径或轨迹。 使用SPECT和/或XCT生成2D患者图像，并且周期性地更新以显示活检仪器的位置和进展。

公开(公告)号：US08712121B2

公开(公告)日：2014-04-29

申请号：US13000030

申请日：2009-06-23

Applicant: Jens Wiegert ,  Matthias Bertram

Inventor： Jens Wiegert ,  Matthias Bertram

IPC: G06K9/00

CPC classification number: G06T11/005 ,  A61B6/032 ,  A61B6/542

Abstract: The present invention relates to an image generation device for generating an image from measured data, wherein image quality is optimized for a region of interest and to an imaging system comprising this image generation device. The image generation device comprises a noise determination unit for determining a distribution of noise in a projection domain of the region of interest, and a dose control unit (32) for determining a dose profile for a radiation source (2) of said image generation device based on said determined distribution of noise by using a noise propagation algorithm. Thereby, signal-to-noise ratio of a reconstructed volume can be improved and is not sensitively dependent on a selected region of interest.

Abstract translation: 本发明涉及一种用于根据测量数据产生图像的图像产生装置，其中对于感兴趣的区域和包括该图像生成装置的成像系统优化图像质量。 该图像生成装置包括用于确定感兴趣区域的投影域中的噪声分布的噪声确定单元，以及用于确定所述图像生成装置的辐射源（2）的剂量分布的剂量控制单元（32） 基于所述确定的噪声分布，使用噪声传播算法。 因此，可以改善重建体积的信噪比并且不敏感地依赖于所选择的感兴趣区域。

公开(公告)号：US20130208957A1

公开(公告)日：2013-08-15

申请号：US13700496

申请日：2011-05-19

Applicant: Steffen Gunther Wiesner ,  Matthias Bertram ,  Ming De Lin

Inventor： Steffen Gunther Wiesner ,  Matthias Bertram ,  Ming De Lin

IPC: A61B5/00

CPC classification number: A61B5/0033 ,  A61B6/507 ,  G06T7/0014 ,  G06T2207/10081 ,  G06T2207/10096 ,  G06T2207/30056 ,  G06T2207/30096

Abstract: The present invention relates to a device (2) for automatically quantifying intravascular embolization success, comprising a registration unit (4) adapted for registering a first image and a second image, a segmentation unit (6) adapted for segmenting a tissue of interest in the first image and in the second image and an evaluation unit (8) for evaluating a deviation of perfusion of the tissue of interest by comparing the first image and the second image. The first image is obtained before an interventional treatment, whereas the second image is obtained after such a treatment. Evaluating may comprise comparing the segments of the first and the second images and thus providing a quantitative measure for a perfusion deviation of the tissue, e.g. the perfusion deviation of a tumorous tissue before and after an embolization treatment.

Abstract translation: 本发明涉及一种用于自动量化血管内栓塞成功的装置（2），包括适用于登记第一图像和第二图像的注册单元（4），适于在所述第一图像和第二图像中分割感兴趣组织的分割单元（6） 第一图像和第二图像;以及评估单元（8），用于通过比较第一图像和第二图像来评估感兴趣组织的灌注偏差。 在介入治疗之前获得第一图像，而在这种治疗后获得第二图像。 评估可以包括比较第一和第二图像的片段，并且因此提供组织灌注偏差的定量测量，例如。 栓塞治疗前后肿瘤组织灌注偏差。

公开(公告)号：US08488902B2

公开(公告)日：2013-07-16

申请号：US12692786

申请日：2010-01-25

Applicant: Matthias Bertram

Inventor： Matthias Bertram

IPC: G06K9/40

CPC classification number: A61B6/032 ,  A61B6/4441 ,  A61B6/482 ,  G06T5/003 ,  G06T5/20 ,  G06T2207/10081

Abstract: The present invention relates to a detection values correction apparatus for correcting detection values of a projection image of a multi-energy imaging system. A scatter contribution providing unit provides scatter contributions for different intensities, different energies and different locations on the detection surface of the detection values. A scatter contributions combining unit combines scatter contributions for correcting a detection value, wherein the combined scatter contributions represent the contribution of the scatter, which is caused by radiation of the other detection values of the projection image, to the detection value to be corrected and wherein the scatter contributions are combined under consideration of the intensity, energy and location on the detection surface of the other detection values. A correction unit scatter corrects the detection value of the projection image by using the combined scatter contributions.

Abstract translation: 本发明涉及一种用于校正多能量成像系统的投影图像的检测值的检测值校正装置。 散射贡献提供单元为检测值的检测表面上的不同强度，不同能量和不同位置提供散射贡献。 散射贡献组合单元组合用于校正检测值的散射贡献，其中组合散射贡献表示由投影图像的其他检测值的辐射引起的散射对待校正的检测值的贡献，并且其中 在考虑其他检测值的检测表面上的强度，能量和位置的情况下组合散射贡献。 校正单位散射通过使用组合散射贡献校正投影图像的检测值。

公开(公告)号：US20110164722A1

公开(公告)日：2011-07-07

申请号：US13063486

申请日：2009-09-09

Applicant: Jens Wiegert ,  Matthias Bertram

Inventor： Jens Wiegert ,  Matthias Bertram

IPC: A61B6/03

CPC classification number: G06T11/005 ,  A61B6/027 ,  A61B6/4291

Abstract: The present invention relates to an imaging apparatus for generating an image of a region of interest of an object. The imaging apparatus comprises a radiation source (2) for emitting radiation (4) and a detector (6) for measuring the radiation (4) after having traversed the region of interest and for generating measured detection values depending on the measured radiation (4). The imaging apparatus further comprises an attenuation element for attenuating the radiation (4) before traversing the region of interest and an attenuation element scatter values providing unit (12) for providing attenuation element scatter values, which depend on scattering of the radiation (4) caused by the attenuation element. A detection values correction unit (17) corrects the measured detection values based on the provided attenuation element scatter values, and a reconstruction unit (18) reconstructs an image of the region of interest from the corrected detection values.

Abstract translation: 本发明涉及一种用于生成对象的感兴趣区域的图像的成像装置。 成像设备包括用于发射辐射的辐射源（2）和用于在穿过感兴趣区域之后测量辐射（4）的检测器（6），并且用于根据所测量的辐射（4）产生测量的检测值， 。 成像装置还包括用于在穿过感兴趣区域之前衰减辐射（4）的衰减元件和用于提供依赖于辐射（4）的散射的衰减元件散射值的衰减元件散射值提供单元（12） 通过衰减元件。 检测值校正单元（17）基于所提供的衰减元件散射值来校正测量的检测值，并且重建单元（18）从校正的检测值重建感兴趣区域的图像。

公开(公告)号：US20110125011A1

公开(公告)日：2011-05-26

申请号：US12942269

申请日：2010-11-09

Applicant: Herfried WIECZOREK ,  Matthias BERTRAM

Inventor： Herfried WIECZOREK ,  Matthias BERTRAM

IPC: A61B5/05

CPC classification number: A61B6/032 ,  A61B6/037 ,  A61B6/4233 ,  A61B6/4417 ,  A61B6/487 ,  A61B6/5235 ,  A61B6/5264 ,  A61B10/0233 ,  A61B34/10 ,  A61B2034/107 ,  A61B2034/2065 ,  A61B2090/364 ,  G01R33/481

Abstract: When performing image-guided biopsy of an anatomical structure in a patient, a target anatomical patient region containing biopsy target is imaged using both SPECT and XCT concurrently. 3D SPECT and XCT image data is fused to generate a fused 3D reference image (34) that is overlaid on 2D patient image(s) generated during the biopsy procedure to generate an overlay image. The overlay image also includes a planned path or trajectory for a biopsy instrument. The 2D patient images are generated using SPECT and/or XCT, and are updated periodically to show biopsy instrument position and progress.

Abstract translation: 当在患者中进行解剖结构的图像引导活组织检查时，使用SPECT和XCT同时成像含有活组织检查靶的目标解剖学患者区域。 3D SPECT和XCT图像数据被融合以产生融合的3D参考图像（34），其被重叠在活检过程中产生的2D患者图像上以产生覆盖图像。 覆盖图像还包括活检仪器的计划路径或轨迹。 使用SPECT和/或XCT生成2D患者图像，并且周期性地更新以显示活检仪器的位置和进展。