公开(公告)号：US20250043357A1

公开(公告)日：2025-02-06

申请号：US18580440

申请日：2022-07-21

Applicant: Mercy Bioanalytics, Inc.

Inventor： Joseph Charles SEDLAK ,  Emily Susan WINN-DEEN ,  Daniel GUSENLEITNER ,  Kelly BIETTE ,  Laura Teresa BORTOLIN ,  Daniel Parker SALEM ,  Anthony David COUVILLON

IPC: C12Q1/6886 ,  C12Q1/6851 ,  G01N33/574

Abstract: The present disclosure in one aspect provides technologies for detection of esophageal cancer, e.g., early detection of esophageal cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to esophageal cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in subjects' bodily fluid samples (e.g., blood samples) that are associated with therapeutic response.

公开(公告)号：US20240369558A1

公开(公告)日：2024-11-07

申请号：US18580427

申请日：2022-07-21

Applicant: Mercy Bioanalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Emily Susan Winn-Deen ,  Daniel Gusenleitner ,  Anthony David Couvillon ,  laura Teresa Bortolin ,  Daniel Parker Salem ,  Kelly Biette ,  Ibukunoluwapo O. Zabroski

IPC: G01N33/574 ,  C12Q1/6886

Abstract: The present disclosure in one aspect provides technologies for detection of breast cancer, e.g., early detection of breast cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to breast cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in subjects' bodily fluid samples (e.g., blood samples) that are associated with therapeutic response.

公开(公告)号：US20230415161A1

公开(公告)日：2023-12-28

申请号：US18465361

申请日：2023-09-12

Applicant: Mercy BioAnalytics, Inc.

Inventor： Christopher Robert Sedlak ,  Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: B01L9/06 ,  A47F7/28 ,  A47F7/00

CPC classification number: B01L9/06 ,  A47F7/283 ,  A47F7/0028 ,  B01L2300/16 ,  B01L2300/12

Abstract: A column tube holder includes: a first side rail extending vertically; a second side rail extending vertically; a first shelf extending horizontally between the first side rail and the second side rail; a second shelf extending horizontally between the first side rail and the second side rail, the second shelf disposed below the first shelf; and a third shelf extending horizontally between the first side rail and the second side rail, the third shelf disposed below the second shelf. The column tube holder is composed of a conductive material, an anti-static material, and/or a static dissipative material.

公开(公告)号：US20230243834A1

公开(公告)日：2023-08-03

申请号：US17793382

申请日：2021-01-16

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: G01N33/574 ,  C12Q1/6886 ,  C12Q1/6804

CPC classification number: G01N33/57449 ,  C12Q1/6804 ,  C12Q1/6886 ,  C12Q2600/158

Abstract: The present disclosure in one aspect provides technologies for detection of ovarian cancer, e.g., early detection of ovarian cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to ovarian cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in woman’s blood samples that are associated with therapeutic response.

公开(公告)号：US20220155304A1

公开(公告)日：2022-05-19

申请号：US17435697

申请日：2020-02-28

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: G01N33/574 ,  G01N33/543 ,  C12Q1/6886 ,  C12Q1/6862 ,  C12Q1/6804

Abstract: The present disclosure provides technologies for target entity detection. One aspect of the present disclosure provides technologies for detection (e.g., early detection) of a disease, disorder, or condition (e.g., cancer). In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject in need thereof, e.g., a subject determined to have or susceptible to cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.