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公开(公告)号：US20050136489A1
公开(公告)日：2005-06-23
申请号：US11013684
申请日：2004-12-17
Applicant: Tzu-Ling Tseng , Ping-Fu Cheng
Inventor： Tzu-Ling Tseng , Ping-Fu Cheng
IPC: G01N33/53 , C07K14/47 , C07K16/18 , G01N21/78 , G01N33/543 , G01N33/567 , G01N33/574 , G01N33/68
CPC classification number: G01N33/57438 , G01N33/6893 , G01N2800/08 , G01N2800/085
Abstract: Biomarkers for liver diseases and method for using the same are provided. For detecting liver cirrhosis and liver cancer, the biomarkers are selected from any one of the amino acid sequences with SEQ ID NO:1 to SEQ ID NO:24 or derivatives or fragments or variants or the combination thereof or the antibodies against the amino acid sequences. Then the biomarkers are further developed into detection kits, such that by detecting the existence of autoantibodies or autoantigens in screened specimens, liver diseases are detected with higher accuracy and sensitivity.
Abstract translation: 提供肝脏疾病的生物标志物及其使用方法。 为了检测肝硬化和肝癌，生物标志物选自SEQ ID NO：1至SEQ ID NO：24的任一氨基酸序列或衍生物或片段或变体或其组合或针对氨基酸序列的抗体 。 然后生物标志物进一步发展为检测试剂盒，通过检测筛选标本中自身抗体或自身抗原的存在，以更高的准确度和灵敏度检测肝脏疾病。
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公开(公告)号：US08465980B2
公开(公告)日：2013-06-18
申请号：US12694575
申请日：2010-01-27
Applicant: Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
Inventor： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
CPC classification number: G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
Abstract: Disclosed is use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
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公开(公告)号：US07986368B2
公开(公告)日：2011-07-26
申请号：US11985226
申请日：2007-11-14
Applicant: Lien-Chen Lin , Ping-Fu Cheng , Chen-Loon Chang
Inventor： Lien-Chen Lin , Ping-Fu Cheng , Chen-Loon Chang
CPC classification number: H04N1/00127 , G06F1/1601 , G06F1/3203 , G06F1/3231 , H04N1/00129 , H04N1/19594 , H04N2201/0422 , Y02D10/173
Abstract: A digital photo frame with photographing function includes a digital frame, a lens module, a bracket, and a copy stand. The digital frame may further include a display module, a frame, a memory module, a control module, an input module, a power supply module, and a sense module. The display module is framed within the frame, and the lens module is disposed at a predetermined location on the frame. A paper photo can be disposed on the copy stand that is pivotally connected to the bracket. The input module can input a control signal to operate and control the lens module to copy photograph the paper photo into a digital photo and store the digital photo in the memory module and further display the digital photo on the display module.
Abstract translation: 具有拍摄功能的数码相框包括数字框架，镜头模块，支架和复印台。 数字帧还可以包括显示模块，帧，存储器模块，控制模块，输入模块，电源模块和感测模块。 显示模块被框架框架内，并且透镜模块设置在框架上的预定位置。 可以将纸张照片放置在枢转地连接到支架的复印台上。 输入模块可以输入控制信号来操作和控制镜头模块，将纸张照片复制到数码照片中，并将数码照片存储在存储模块中，并在显示模块上进一步显示数码照片。
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Patent Agency Ranking
公开(公告)号：US20110086371A1
公开(公告)日：2011-04-14
申请号：US12972936
申请日：2010-12-20
Applicant: Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
Inventor： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
IPC: G01N33/53 , C07K16/18 , G01N33/566
CPC classification number: G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
Abstract: Use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
Abstract translation: 使用尿液和血清生物标志物诊断糖尿病肾病，分期糖尿病肾病，监测糖尿病肾病进展，评估糖尿病肾病治疗效果。 这些生物标志物包括尿前体α-2-HS-糖蛋白，尿α-1抗胰蛋白酶，尿α-1酸糖蛋白，尿骨桥蛋白，血清骨桥蛋白，其片段及其组合。
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公开(公告)号：US20110079077A1
公开(公告)日：2011-04-07
申请号：US12969039
申请日：2010-12-15
Applicant: Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
Inventor： Wei-Ya Lin , Mary Ya-Ping Yeh , Tzu-Ling Tseng , Ping-Fu Cheng , Tsai-Wei Hsu , Hung-Yi Li , Yi-Ting Chen , Yuh-Feng Ling , Jin-Shuen Chen , Yen-Peng Li
IPC: G01N1/10
CPC classification number: G01N33/6893 , G01N2333/4728 , G01N2333/52 , G01N2333/71 , G01N2333/8125 , G01N2800/347 , G01N2800/52 , G01N2800/56
Abstract: Use of urine and serum biomarkers in diagnosing diabetic nephropathy, staging diabetic nephropathy, monitoring diabetic nephropathy progress, and assessing efficacy of diabetic nephropathy treatments. These biomarkers include urine precursor alpha-2-HS-glycoprotein, urine alpha-1 antitrypsin, urine alpha-1 acid glycoprotein, urine osteopontin, serum osteopontin, their fragments, and combinations thereof.
Abstract translation: 使用尿液和血清生物标志物诊断糖尿病肾病，分期糖尿病肾病，监测糖尿病肾病进展，评估糖尿病肾病治疗效果。 这些生物标志物包括尿前体α-2-HS-糖蛋白，尿α-1抗胰蛋白酶，尿α-1酸糖蛋白，尿骨桥蛋白，血清骨桥蛋白，其片段及其组合。
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公开(公告)号：US20090183412A1
公开(公告)日：2009-07-23
申请号：US12286198
申请日：2008-09-29
Applicant: Ping-Fu Cheng , Pei-Yu Wu , Ming-Chang Chang
Inventor： Ping-Fu Cheng , Pei-Yu Wu , Ming-Chang Chang
CPC classification number: H04N1/00347 , F16C11/0604 , H04N1/00562 , H04N2201/0063 , H04N2201/0081 , H04N2201/0089
Abstract: A digital picture frame having a scanning function comprises a digital picture frame, a scanning module, and a universal supporting member, wherein the universal supporting member further comprises a fixing seat, a ball, a friction unit and a support. The fixing seat is a spherical cavity formed in the digital picture frame for receiving the ball therein. The ball has a through hole penetrating a center of the ball. The friction unit is provided between the fixing seat and the ball. The support has a connecting portion at an end thereof which keeps a predetermined included angle with the support, wherein the connecting portion is connected to the through hole of the ball via an opening formed on a back panel of the digital picture frame, and the friction unit generates a predetermined frictional resistance between the fixing seat and the ball connected with the support, so that the support can change a supporting angle between the support and the digital picture frame, thereby changing a viewing angle of the digital picture frame. Moreover, the scanning module can be used to scan a picture and generate a digital image thereof for display on a display module.
Abstract translation: 具有扫描功能的数字图像帧包括数字相框，扫描模块和通用支撑构件，其中通用支撑构件还包括固定座，球，摩擦单元和支撑件。 固定座是形成在数字相框中的用于在其中接收球的球形腔。 球具有穿透球的中心的通孔。 摩擦单元设置在固定座和球之间。 支撑件在其端部具有与支撑件保持预定夹角的连接部分，其中连接部分通过形成在数字相框的后面板上的开口连接到球的通孔，并且摩擦 单元在固定座和与支撑件连接的球之间产生预定的摩擦阻力，使得支撑件可以改变支撑件和数字画框之间的支撑角度，从而改变数字画框的视角。 此外，扫描模块可用于扫描图像并生成其数字图像以在显示模块上显示。
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公开(公告)号：US20090059052A1
公开(公告)日：2009-03-05
申请号：US11985226
申请日：2007-11-14
Applicant: Lien-Chen Lin , Ping-Fu Cheng , Chen-Loon Chang
Inventor： Lien-Chen Lin , Ping-Fu Cheng , Chen-Loon Chang
IPC: H04N5/222
CPC classification number: H04N1/00127 , G06F1/1601 , G06F1/3203 , G06F1/3231 , H04N1/00129 , H04N1/19594 , H04N2201/0422 , Y02D10/173
Abstract: A digital photo frame with photographing function includes a digital frame, a lens module, a bracket, and a copy stand. The digital frame may further include a display module, a frame, a memory module, a control module, an input module, a power supply module, and a sense module. The display module is framed within the frame, and the lens module is disposed at a predetermined location on the frame. A paper photo can be disposed on the copy stand that is pivotally connected to the bracket. The input module can input a control signal to operate and control the lens module to copy photograph the paper photo into a digital photo and store the digital photo in the memory module and further display the digital photo on the display module.
Abstract translation: 具有拍摄功能的数码相框包括数字框架，镜头模块，支架和复印台。 数字帧还可以包括显示模块，帧，存储器模块，控制模块，输入模块，电源模块和感测模块。 显示模块被框架框架内，并且透镜模块设置在框架上的预定位置。 可以将纸张照片放置在枢转地连接到支架的复印台上。 输入模块可以输入控制信号来操作和控制镜头模块，将纸张照片复制到数码照片中，并将数码照片存储在存储模块中，并在显示模块上进一步显示数码照片。
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公开(公告)号：US20070154968A1
公开(公告)日：2007-07-05
申请号：US11321516
申请日：2005-12-29
Applicant: Tzu-Ling Tseng , Pei-Hsiu Liao , Ping-Fu Cheng , Shih-Feng Tsai , Hou-Chang Chiu
Inventor： Tzu-Ling Tseng , Pei-Hsiu Liao , Ping-Fu Cheng , Shih-Feng Tsai , Hou-Chang Chiu
IPC: G01N33/53
CPC classification number: G01N33/564 , G01N33/6854 , G01N2800/10 , G01N2800/28 , G01N2800/2835 , Y10S436/811
Abstract: The present invention relates to methods of diagnosing myasthenia gravis in a subject, by determining an amount of at least one autoantibody that specifically binds one or more autoantigens selected from heat-shock protein 60 (hsp60), heat-shock protein 90, alpha isoform (hsp90α), and heat-shock protein 90, beta isoform (hsp90β). The invention also provides diagnostic kits for identifying a subject having myasthenia gravis.
Abstract translation: 本发明涉及通过确定特异性结合一种或多种选自热休克蛋白60（hsp60），热休克蛋白90，α同工型（hsp60）的自身抗原的至少一种自身抗体的量来诊断受试者的重症肌无力的方法 hsp90alpha）和热休克蛋白90，β异构体（hsp90beta）。 本发明还提供了用于鉴定重症肌无力的受试者的诊断试剂盒。
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