公开(公告)号：US20050266431A1

公开(公告)日：2005-12-01

申请号：US11064246

申请日：2005-02-22

申请人： William Grosse ,  John Alsobrook ,  Denise Lepley ,  Catherine Burgess ,  Joel Bader ,  Aruna Bansal ,  Carol Pena ,  Richard Shimkets ,  Ramesh Kekuda ,  Bryan Zerhusen ,  Glennda Smithson ,  David Anderson ,  Mei Zhong ,  Charles Miller ,  Corine Vernet ,  Tord Hjalt

发明人： William Grosse ,  John Alsobrook ,  Denise Lepley ,  Catherine Burgess ,  Joel Bader ,  Aruna Bansal ,  Carol Pena ,  Richard Shimkets ,  Ramesh Kekuda ,  Bryan Zerhusen ,  Glennda Smithson ,  David Anderson ,  Mei Zhong ,  Charles Miller ,  Corine Vernet ,  Tord Hjalt

IPC分类号： A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/47 ,  C12N1/21 ,  C12Q1/68 ,  C07H21/04 ,  C07K16/40 ,  C12N9/12 ,  C12N15/09 ,  C12P21/06

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00

摘要： Disclosed herein is a nucleic acid sequence that encodes a novel polypeptide. Also disclosed is a polypeptide encoded by the nucleic acid sequence, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving this novel human nucleic acid and protein. The invention also provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.

摘要翻译： 本文公开了编码新型多肽的核酸序列。 还公开了由核酸序列编码的多肽和免疫特异性结合多肽的抗体以及前述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明还公开了用于诊断，治疗和预防涉及该新型人核酸和蛋白质的病症的治疗，诊断和研究方法。 本发明还提供含有针对转录的人序列鉴定的单核苷酸多态性的核酸，以及使用该核酸的方法。

公开(公告)号：US20050244868A1

公开(公告)日：2005-11-03

申请号：US11096051

申请日：2005-03-30

申请人： Ramesh Kekuda ,  Timothy MacLachlan ,  Meera Patturajan ,  Luca Rastelli ,  Seth Ettenberg ,  Corine Vernet

发明人： Ramesh Kekuda ,  Timothy MacLachlan ,  Meera Patturajan ,  Luca Rastelli ,  Seth Ettenberg ,  Corine Vernet

IPC分类号： C07H21/04 ,  C07K14/705 ,  C07K14/82 ,  C07K16/30 ,  C12Q1/68 ,  G01N33/574

CPC分类号： C07K14/70571

摘要： Disclosed herein are novel Ten-M3 polynucleotides encoding novel polypeptides and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

摘要翻译： 本文公开了编码新颖多肽的免疫特异性结合的新的多肽和抗体，以及多肽特异性的新型多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 载体，宿主细胞，抗体和用于产生多肽和多核苷酸的重组方法，以及使用它们的方法也包括在内。 本发明还公开了用于诊断，治疗和预防与这些新型人核酸和蛋白质中的任一种相关的病症的治疗，诊断和研究方法。