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公开(公告)号：US3912807A
公开(公告)日：1975-10-14
申请号：US46214874
申请日：1974-04-18
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , GRANT NORMAN H , CLARK DONALD E
CPC classification number: A61K38/31 , A61K38/28 , Y10S514/806 , Y10S930/16 , A61K38/00
Abstract: An injectable composition comprising insulin combined with somatostatin, reduced somatostatin, or polymeric reduced somatostatin in water is described as being useful for the treatment of diabetes mellitus.
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12.发明授权6-(2-amino-hexahydro-2-indancarboxyamido) and 6-(1,2,3,4,5,6,7,8,9,10-decahydronaphthalene-2-amino-2-carboxamido) penicillanic acids 失效6-（2-氨基 - 十六氢-2-羟基羧基甲酰胺）和6-（1,2,3,4,5,6,7,8,9,10-十氢萘二甲醛-2-氨基-2-羧基甲酰胺）苯胺
公开(公告)号：US3621011A
公开(公告)日：1971-11-16
申请号：US3621011D
申请日：1969-08-22
Applicant: AMERICAN HOME PROD
Inventor： RUSSELL PETER B , ALBURN HARVEY E , GRANT NORMAN H
IPC: A61K31/43 , C07D499/74 , C07D99/16
CPC classification number: A61K31/43 , C07D499/74 , Y02P20/55
Abstract: The compounds are 6-(2-amino-hexahydro-2-indancarboxamido) penicillanic acids and 6-(1,2,3,4,5,6,7,8,9,10decahydronaphthalene-2-amino-2-carboxamido) pencillanic acids, which have broad spectrum antimicrobial activity against both gram-positive and gram-negative strains of bacteria, including penicillin-resistant staphylococci. The compounds are also characterized by being relatively acid-resistant, thereby to be effective on oral administration, and by low water solubility which makes them useful in repository injectable dosage forms without the necessity for forming salts thereof with organic bases.
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公开(公告)号：US3574742A
公开(公告)日：1971-04-13
申请号：US3574742D
申请日：1968-06-25
Applicant: AMERICAN HOME PROD
Inventor： LAPIDUS MILTON , GRANT NORMAN H , ALBURN HARVEY E
IPC: C07C103/86
Abstract: AMINOALICYCLIC CARBOXHYDRAZIDES ARE PREPARED BY THE REACTION OF AN AMINOALICYCLIC CARBOXYLIC ACID ANHYDRIDE WITH A HYDRAZINE. THE COMPOUNDS HAVE BIOCHEMICAL ACTIVITY AND ARE USEFUL AS IMMUNO-SUPPRESSIVE AGENTS.
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公开(公告)号：US3532744A
公开(公告)日：1970-10-06
申请号：US3532744D
申请日：1967-07-28
Applicant: AMERICAN HOME PROD
Inventor： FLETCHER HORACE , RUSSELL PETER B , ALBURN HARVEY E
IPC: C07D235/02 , C07D263/52 , C07D499/00 , C07C101/04
CPC classification number: C07D235/02 , C07D263/52 , C07D499/00
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公开(公告)号：US3509208A
公开(公告)日：1970-04-28
申请号：US3509208D
申请日：1966-12-16
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , GRANT NORMAN H , CLARK DONALD E
IPC: C07C233/12 , C07C101/44
CPC classification number: C07C233/12 , Y10S514/814 , Y10S514/825 , Y10S514/863 , Y10S514/894 , Y10S514/903
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Patent Agency Ranking
公开(公告)号：US3455784A
公开(公告)日：1969-07-15
申请号：US3455784D
申请日：1966-03-11
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , GRANT NORMAN H
IPC: C07D499/00 , C12D13/06 , C12D9/06
CPC classification number: C07D499/00
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公开(公告)号：US3350407A
公开(公告)日：1967-10-31
申请号：US38002464
申请日：1964-07-02
Applicant: AMERICAN HOME PROD
Inventor： HORACE FLETCHER , ALBURN HARVEY E
IPC: C07D231/12 , C07D521/00
CPC classification number: C07D231/12 , C07D233/56 , C07D249/08 , Y10S514/866 , Y10S514/869
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公开(公告)号：US3272715A
公开(公告)日：1966-09-13
申请号：US21057562
申请日：1962-07-17
Applicant: AMERICAN HOME PROD
Inventor： GRANT NORMAN H , ALBURN HARVEY E
IPC: C07D499/42
CPC classification number: C07D499/42 , Y10S435/829 , Y10S435/849 , Y10S435/929
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公开(公告)号：US3268519A
公开(公告)日：1966-08-23
申请号：US35809664
申请日：1964-04-07
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , GRANT NORMAN H
IPC: C07D499/00 , C07D499/64
CPC classification number: C07D499/00
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公开(公告)号：US3268515A
公开(公告)日：1966-08-23
申请号：US35806664
申请日：1964-04-07
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , GRANT NORMAN H
IPC: C07D499/00 , C07D499/74
CPC classification number: C07D499/00
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