公开(公告)号：US3574742A

公开(公告)日：1971-04-13

申请号：US3574742D

申请日：1968-06-25

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON ,  GRANT NORMAN H ,  ALBURN HARVEY E

IPC: C07C103/86

Abstract: AMINOALICYCLIC CARBOXHYDRAZIDES ARE PREPARED BY THE REACTION OF AN AMINOALICYCLIC CARBOXYLIC ACID ANHYDRIDE WITH A HYDRAZINE. THE COMPOUNDS HAVE BIOCHEMICAL ACTIVITY AND ARE USEFUL AS IMMUNO-SUPPRESSIVE AGENTS.

公开(公告)号：US3478145A

公开(公告)日：1969-11-11

申请号：US3478145D

申请日：1967-12-18

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON

IPC: A61K39/145 ,  A61K23/00

CPC classification number: A61K39/145 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/70 ,  C12N2760/16134 ,  C12N2760/16234

公开(公告)号：US3703543A

公开(公告)日：1972-11-21

申请号：US3703543D

申请日：1969-11-05

Applicant: AMERICAN HOME PROD

Inventor： ALBURN HARVEY E ,  CLARK DONALD E ,  GRANT NORMAN H ,  LAPIDUS MILTON

IPC: C07C103/30 ,  A61K27/00

Abstract: THE COMPOUNDS ARE HYDROXAMIC ACIDS OF ALICYCLIC AMINO ACIDS, AND ESTERS OF SAID COMPOUNDS, ALL OF WHICH HAVE VALUABLE PHARMACODYNAMIC PROPERTIES IN THAT THEY SUPPRESS THE IMMUNE RESPONSE IN WARM-BLOODED ANIMALS.

公开(公告)号：US3504019A

公开(公告)日：1970-03-31

申请号：US3504019D

申请日：1967-02-20

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON ,  GRANT NORMAN H ,  ALBURN HARVEY E

IPC: C07C405/00 ,  C07C61/36

CPC classification number: C07C405/00

公开(公告)号：US3703542A

公开(公告)日：1972-11-21

申请号：US3703542D

申请日：1969-11-05

Applicant: AMERICAN HOME PROD

Inventor： ALBURN HARVEY E ,  CLARK DONALD E ,  GRANT NORMAN H ,  LAPIDUS MILTON

IPC: C07C103/30 ,  A61K27/00

Abstract: THE COMPOUNDS ARE HYDROXAMIC ACIDS OF ALICYCLIC AMINO ACIDS, AND ESTERS OF SAID COMPOUNDS, ALL OF WHICH HAVE VALUABLE PHARMACODYNAMIC PROPERTIES IN THAT THEY RELIEVE HYPERGLYCEMIA IN WARM-BLOODED AMINALS.

公开(公告)号：US3504020A

公开(公告)日：1970-03-31

申请号：US3504020D

申请日：1967-10-04

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON ,  GRANT NORMAN H ,  ROSENTHALE MARVIN E ,  ALBURN HARVEY E

IPC: C07C405/00 ,  C07C159/00 ,  A61K27/00 ,  C07C59/18

CPC classification number: C07C405/00

公开(公告)号：US3427383A

公开(公告)日：1969-02-11

申请号：US3427383D

申请日：1965-08-13

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON ,  FAGAN RAYMOND

IPC: A61K31/70 ,  C07D475/10 ,  A61K23/02 ,  A61K27/00 ,  C07G7/00

CPC classification number: C07D475/10 ,  A61K31/70

公开(公告)号：US3644638A

公开(公告)日：1972-02-22

申请号：US3644638D

申请日：1970-08-24

Applicant: AMERICAN HOME PROD

Inventor： ROSENTHALE MARVIN E ,  LAPIDUS MILTON

IPC: A61K9/00 ,  A61K31/557 ,  C07C405/00 ,  A61K27/00

CPC classification number: A61K9/0078 ,  A61K9/008 ,  C07C405/00

Abstract: COMPOSITIONS COMPRISING COMPOUNDS SELECTED FROM THE FAMILY OF PROSTANOIC ACIDS AND ESTERS OR SALTS THEREOF AND A PHARMACOLIGICAL CARRIER ARE USEFUL TO TREAT BRONCHIAL SPASM IN WARM-BLOODED ANIMALS AND TO PROMOTE FREE BREATHING, ESPECIALLY WHEN ADMINISTERED BY THE INHALATION OF AN AEROSOL MIST.

公开(公告)号：US3622663A

公开(公告)日：1971-11-23

申请号：US3622663D

申请日：1970-02-11

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON

IPC: A61K39/145 ,  B01J20/04 ,  C12N7/02 ,  G01N33/483 ,  B01J11/82 ,  C01B25/32

CPC classification number: G01N30/482 ,  A61K39/12 ,  A61K39/145 ,  B01J20/048 ,  B01J20/281 ,  B01J2220/52 ,  C12N7/00 ,  C12N2760/16151

Abstract: This invention relates to an alkali treated calcium dihydrogen orthophosphate monohydrate adsorbent. Further, it concerns an alkali and trimetaphosphate treated calcium dihydrogen orthophosphate monohydrate adsorbent. Still further, it relates to the processes for the preparation of these adsorbents and to their use in virus purification.

公开(公告)号：US3509070A

公开(公告)日：1970-04-28

申请号：US3509070D

申请日：1968-06-13

Applicant: AMERICAN HOME PROD

Inventor： LAPIDUS MILTON

IPC: A61K39/145 ,  C12N7/02 ,  G01N33/483 ,  B01J11/82 ,  A61K23/00 ,  C01B25/32

CPC classification number: G01N30/482 ,  B01J2220/54 ,  C12N7/00 ,  C12N2760/16151