公开(公告)号：US20220378615A1

公开(公告)日：2022-12-01

申请号：US17664034

申请日：2022-05-18

Applicant: AMO Development, LLC

Inventor： Alireza Malek Tabrizi ,  James Hill ,  Nima Khatibzadeh ,  Pavel Vodkin ,  Harvey Liu ,  Hong Fu ,  Griffith Altmann

IPC: A61F9/008

Abstract: A method implemented in an ophthalmic surgical laser system for forming a corneal flap in a patient's eye with improved bubble management. The flap includes a horizontal bed and a vertical or near vertical side cut around the periphery of the bed except for an uncut hinge area. The side cut has a bubble barrier layer that can prevent bubbles formed by the laser-tissue interaction from escaping into an interface between the corneal and the patient interface lens. In some embodiments, the bubble barrier layer is a thin uncut layer, located in the epithelium of the cornea, that separates the side cut into two portions. In other embodiments, the side cut does not reach the anterior corneal surface, leaving an uncut bubble barrier layer located with the epithelium. In other embodiments, an additional side cut portion is formed through the uncut bubble barrier layer as the last step.

公开(公告)号：US20220175581A1

公开(公告)日：2022-06-09

申请号：US17457419

申请日：2021-12-02

Applicant: AMO Development, LLC

Inventor： Andrew Voorhees ,  Harvey Liu ,  Hong Fu ,  Alireza Malek Tabrizi ,  Nima Khatibzadeh ,  Deepali Mehta-Hurt ,  Cynthia Villanueva ,  James Hill ,  Alisyn Facemire

IPC: A61F9/008

Abstract: A method implemented in an ophthalmic surgical laser system that employs a resonant scanner, scan line rotator, and XY- and Z-scanners, for forming a corneal flap in a patient's eye with improved bubble management during each step of the flap creation process. A pocket cut is formed first below bed level, followed by the bed connected to the pocket cut, then by a side cut extending from the bed to the anterior corneal surface. The pocket cut includes a pocket region located below the bed level and a ramp region connecting the pocket region to the bed. The bed is formed by a hinge cut and a first ring cut at lower laser energies, followed by a bed cut and then a second ring cut, which ensures that any location in the flap bed is cut twice to minimize tissue adhesion. The side cut is formed by multiple side-cut layers at different depths which are joined together. All cuts are formed by scanning a laser scan line generated by the resonant scanner.

公开(公告)号：US11253398B2

公开(公告)日：2022-02-22

申请号：US15630629

申请日：2017-06-22

Applicant: AMO Development, LLC

Inventor： Alireza Malek Tabrizi ,  Hong Fu ,  James E. Hill ,  Mohammad Saidur Rahaman ,  Zenon Witowski

IPC: A61F9/008 ,  A61B18/00 ,  A61B18/20

Abstract: Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in a corneal stroma.

公开(公告)号：US20160067095A1

公开(公告)日：2016-03-10

申请号：US14848733

申请日：2015-09-09

Applicant: AMO Development, LLC

Inventor： Hong Fu ,  Patrick De Guzman ,  Robert Heitel ,  Alireza Malek Tabrizi

IPC: A61F9/008

CPC classification number: A61F9/00836 ,  A61F9/00825 ,  A61F2009/00844 ,  A61F2009/00872 ,  A61F2009/00897

Abstract: Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for creating synchronized three-dimensional laser incisions. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to synchronize an oscillation of the XY-scan device and an oscillation of the Z-device to form an angled three-dimensional laser tissue dissection.

Abstract translation: 本发明的实施例一般涉及眼科激光程序，更具体地，涉及用于产生同步三维激光切割的系统和方法。 在一个实施例中，眼科外科激光系统包括用于将脉冲激光束传送到受试者眼睛中的目标的激光递送系统，用于偏转脉冲激光束的XY扫描装置，Z扫描装置，以修改 脉冲激光束的焦点，以及被配置为使XY扫描装置的振荡与Z装置的振荡同步以形成成角度的三维激光组织剥离的控制器。

公开(公告)号：US20240335323A1

公开(公告)日：2024-10-10

申请号：US18737900

申请日：2024-06-07

Applicant: AMO Development, LLC

Inventor： Andrew Voorhees ,  Alireza Malek Tabrizi ,  Hong Fu ,  Cynthia Villanueva ,  Nima Khatibzadeh ,  Deepali Mehta-Hurt ,  James Hill ,  Li Chen ,  Li Bing

IPC: A61F9/008

CPC classification number: A61F9/00827 ,  A61F2009/00872 ,  A61F2009/00897

Abstract: In laser-assisted corneal lenticule extraction procedures, the lenticule incision profile includes anterior and posterior lenticule incisions, with one or more of the following features: plano transition zone outside the optical zone, to improve mating of anterior and posterior incision surfaces after lenticule extraction; shallow arcuate incisions above the anterior incision and near the lenticule edge, to improve surface mating; separate ring cut intersecting the anterior and posterior incisions in the transition zone, to reduce tissue bridges and minimize tear at the lenticule edges and facilitate easy lenticule extraction; larger posterior incision, which includes a pocket zone outside the lenticule edge, for better surface mating and bubble management during cutting; and a separate ring shaped pocket cut intersecting the pocket zone of the posterior incision, for bubble management. An entry cut can intersect either the pocket zone of the posterior incision or an entry extension zone of the anterior incision.

公开(公告)号：US20230181368A1

公开(公告)日：2023-06-15

申请号：US17643812

申请日：2021-12-10

Applicant: AMO Development, LLC

Inventor： Cynthia Villanueva ,  Deepali Mehta-Hurt ,  Hong Fu ,  Jiandong Xu ,  Alireza Malek Tabrizi ,  Griffith Altmann

IPC: A61F9/008 ,  G02B26/10

CPC classification number: A61F9/00827 ,  G02B26/101 ,  G02B26/108 ,  A61F2009/0087 ,  A61F2009/00897

Abstract: An ophthalmic surgical laser system and method for forming a lenticule in a subject's eye using “fast-scan-slow-sweep” scanning scheme. A high frequency scanner forms a fast scan line, which is placed by the XY and Z scanners at a location tangential to a parallel of latitude of the surface of the lenticule. The XY and Z scanners then move the scan line in a slow sweep trajectory along a meridian of longitude of the surface of the lenticule in one sweep. Multiple sweeps are performed along different meridians to form the entire lenticule surface, and a prism is used to change the orientation of the scan line of the high frequency scanner between successive sweeps. In each sweep, within a central area of the lenticule where the sweeps overlap, the laser is periodically blanked (or delivered with significantly reduced pulse energy) to reduce the total energy delivered in that area.

公开(公告)号：US20230127288A1

公开(公告)日：2023-04-27

申请号：US18145017

申请日：2022-12-22

Applicant: AMO DEVELOPMENT, LLC

Inventor： Alireza Malek Tabrizi ,  Hong Fu ,  James E. Hill ,  Zenon Witowski

IPC: A61F9/008

Abstract: An ophthalmic surgical laser system includes: a laser that produces a pulsed laser beam having a pulse energy and pulse repetition rate; a high frequency fast scanner; an XY-scan device; a Z-scan device; and a controller. The controller controls the high frequency scanner to produce a scan line having a scan width; controls the XY-scan device and the Z-scan device to carry out of first sweep of the scan line in a first sweep direction and to carry out a second sweep of the scan line in a second sweep direction that is not parallel to the first sweep direction thereby defining an overlap region. At least one of the pulse energy, repetition rate, XY-scan speed, and the scan width is varied so as to accelerate the cutting speed and reduce the exposure of ophthalmic tissue in the overlap region to multiple exposures of laser pulses configured to modify ophthalmic tissue.

公开(公告)号：US11564838B2

公开(公告)日：2023-01-31

申请号：US16923496

申请日：2020-07-08

Applicant: AMO Development, LLC

Inventor： Hong Fu ,  Alireza Malek Tabrizi

IPC: A61F9/008 ,  A61B3/107 ,  A61B3/00

Abstract: Embodiments of this invention generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in the subject's eye, where each of the top and bottom lenticular incision includes a center concave portion and an edge transition portion that has a smooth convex shape and is smoothly joined to the center concave portion.

公开(公告)号：US20220168144A1

公开(公告)日：2022-06-02

申请号：US17651242

申请日：2022-02-15

Applicant: AMO Development, LLC

Inventor： Alireza Malek Tabrizi ,  Hong Fu ,  James E. Hill ,  Mohammad Saidur Rahaman ,  Zenon Witowski

IPC: A61F9/008 ,  A61B18/20

Abstract: Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incision. In an embodiment, an ophthalmic surgical laser system comprises a laser delivery system for delivering a pulsed laser beam to a target in a subject's eye, an XY-scan device to deflect the pulsed laser beam, a Z-scan device to modify a depth of a focus of the pulsed laser beam, and a controller configured to form a top lenticular incision and a bottom lenticular incision of a lens in a corneal stroma.

公开(公告)号：US20220096274A1

公开(公告)日：2022-03-31

申请号：US17449249

申请日：2021-09-28

Applicant: AMO Development, LLC

Inventor： Hong Fu ,  Alireza Malek Tabrizi

IPC: A61F9/008

Abstract: A corneal lenticule extraction procedure provides convenient re-treatment options when treatment interruptions occur. The procedure is executed by an ophthalmic laser system according to a programmed treatment plan, which defines an entry cut, an optional ring cut, a bottom lenticule incision having an optical zone, and a flat top bed incision. If an interruption occurs during the entry cut, the treatment plan is re-aligned with the partially formed entry cut and continued, or with a new entry cut placed at a different angular position. If an interruption occurs during the ring cut, the treatment plan is revised to define a larger ring cut concentric with the partially formed ring cut. If an interruption occurs during the bottom or top incision, the depth of the partially formed bottom or top incision is measured, and the treatment plan is revised to form a deeper bottom incision or a shallower top incision, respectively.