利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

227 条记录 (耗时 0.04 秒)

    Process for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives
    11.
    再颁专利
    Process for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives 有权

    公开(公告)号：USRE39333E1

    公开(公告)日：2006-10-10

    申请号：US10705665

    申请日：2000-06-02

    申请人： Akira Nishiyama ,  Kenji Inoue

    发明人： Akira Nishiyama ,  Kenji Inoue

    IPC分类号： C07C69/66 ,  C07C59/185

    CPC分类号： C12P7/62 ,  C07B2200/07 ,  C07C67/343 ,  C07C253/30 ,  C07D319/06 ,  C07C69/716 ,  C07C255/21 ,  C07C69/738

    摘要： This invention provides a process for producing a 5-hydroxy-3-oxopentanoic acid, a useful pharmaceutical intermediate, easily from a readily available, inexpensive starting material without using any extraordinary production equipment such as a very-low-temperature reactor.Thus, this invention provides a process for producing a 5-hydroxy-3-oxopentanoic acid which comprises permitting a lithium amide to act upon a mixture of an acetic acid ester and a 3-hydroxypropionic acid derivative at not below −20° C. Further, this invention also provides a process for producing a 5-hydroxy-3-oxopentanoic acid which comprises treating a mixture of an acetic acid ester and a 3-hydroxypropionic acid derivative with a Grignard reagent to prepare a mixture of a compound and an acetic acid ester of the above formula (I), and permitting a lithium amide to act upon the mixture at a temperature not below −20° C. This invention provides a process for producing a 5-hydroxy-3-oxopentanoic acid, a useful pharmaceutical intermediate, easily from a readily available, inexpensive starting material without using any extraordinary production equipment such as a very-low temperature reactor. Thus, this invention provides a process for producing a 5-hydroxy-3-oxopentanoic acid which comprises permitting a lithium amide to act upon a mixture of an acetic acid ester and a 3-hydroxypropionic acid derivative at not below −20° C. Further, this invention also provides a process for producing a 5-hydroxy-3-oxopentanoic acid which comprises treating a mixture of an acetic acid ester and a 3-hydroxypropionic acid derivative with a Grignard reagent to prepare a mixture of a compound and an acetic acid ester of the above formula (I), and permitting a lithium amide to act upon the mixture at a temperature not below −20° C.

    Processes for producing .alpha.-halo ketones, .alpha.-halohydrins and epoxides
    12.
    发明授权
    Processes for producing .alpha.-halo ketones, .alpha.-halohydrins and epoxides 失效
    制备α-卤代酮，α-卤代醇和环氧化物的方法

    公开(公告)号：US5929284A

    公开(公告)日：1999-07-27

    申请号：US722102

    申请日：1996-12-18

    申请人： Akira Nishiyama ,  Tadashi Sugawa ,  Hajime Manabe ,  Kenji Inoue ,  Noritaka Yoshida

    发明人： Akira Nishiyama ,  Tadashi Sugawa ,  Hajime Manabe ,  Kenji Inoue ,  Noritaka Yoshida

    IPC分类号： C07C29/143 ,  C07C45/48 ,  C07C269/06 ,  C07C319/20 ,  C07C323/43 ,  C07D303/36 ,  C07C45/00

    CPC分类号： C07D303/36 ,  C07C269/06 ,  C07C29/143 ,  C07C319/20 ,  C07C45/48

    摘要： Processes for efficiently producing .alpha.-halo ketones, .alpha.-halohydrins and epoxides on an industrial scale. The prosesses include one for producing an .alpha.-halo ketone of general formula (3) by decarboxylating a product of reaction between a carboxilic acid derivative of general formula (1) and a metal enolate prepared from an .alpha.-haloacetic acid of general formula (2) or an acceptable salt thereof, one for producing an by reducing the .alpha.-halo ketone (3), and one for producing an epoxide (13) by treating the .alpha.-halohydrin (11) with a base to effect ring closure. The above prosesses are particularly suitable for producing optically active .alpha.-halo ketones, .alpha.-halohydrins and epoxides from the corresponding .alpha.-amino acid derivatives. ##STR1##

    摘要翻译： PCT No.PCT / JP96 / 00212 Sec。 371日期：1996年12月18日 102（e）1996年12月18日日期PCT 1996年2月2日PCT PCT。 第WO96 / 23756号公报 日期1996年8月8日工业规模高效生产α-卤代酮，α-卤代醇和环氧化物的方法。 前药包括通过使通式（1）的羧酸衍生物与由通式（2）的α-卤代乙酸制备的金属烯醇化物脱羧的方法来制备通式（3）的α-卤代酮， ）或其可接受的盐，其中通过用碱来还原α-卤代酮（3）和通过用碱处理α-卤代醇（11）来制备环氧化物（13）来制备，以实现闭环。 上述产品特别适用于从相应的α-氨基酸衍生物制备光学活性的α-卤代酮，α-卤代醇和环氧化物。

    Process for production of 3-(3-pyridyl)-1-propanol derivatives
    13.
    发明授权
    Process for production of 3-(3-pyridyl)-1-propanol derivatives 失效
    3-（3-吡啶基）-1-丙醇衍生物的制备方法

    公开(公告)号：US06388086B1

    公开(公告)日：2002-05-14

    申请号：US09631678

    申请日：2000-08-02

    申请人： Akira Nishiyama ,  Kazumi Okuro ,  Kenji Inoue

    发明人： Akira Nishiyama ,  Kazumi Okuro ,  Kenji Inoue

    IPC分类号： C07D21330

    CPC分类号： C07D213/30

    摘要： A process for producing a 3-(3-pyridyl)-1-propanol derivative of use as a pharmaceutical intermediate expediently with an inexpensive material is provided. The process is concerned with a 3-(3-pyridyl)-1-propanol derivative (3): in the formula, R1 represents an alkyl group of 1 to 20 carbon atoms, aryl group of 6 to 20 carbon atoms or aralkyl group of 7 to 20 carbon atoms, which may be substituted, and comprises reacting a 3-methylpyridine with a strong base to prepare a 3-methylpyridine metal (1): in the formula, M represents lithium, sodium, potassium or a magnesium halide, where the halide is chloride or bromide, and then reacting said metal salt with an epoxy compound (2):

    摘要翻译： 提供了以便宜的材料制备用作药物中间体的3-（3-吡啶基）-1-丙醇衍生物的方法。 该方法涉及3-（3-吡啶基）-1-丙醇衍生物（3）：式中，R1表示碳原子数为1〜20的烷基，碳原子数为6〜20的芳基或芳烷基 可以被取代的7至20个碳原子，并且使3-甲基吡啶与强碱反应以制备3-甲基吡啶金属（1）：在该式中，M表示锂，钠，钾或卤化镁，其中 卤化物是氯化物或溴化物，然后使所述金属盐与环氧化合物（2）反应：

    Processes for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives
    16.
    发明授权
    Processes for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives 有权
    5-羟基-3-氧代戊酸衍生物的制备方法

    公开(公告)号：US06340767B1

    公开(公告)日：2002-01-22

    申请号：US09762215

    申请日：2001-04-05

    申请人： Akira Nishiyama ,  Kenji Inoue

    发明人： Akira Nishiyama ,  Kenji Inoue

    IPC分类号： C07C5100

    CPC分类号： C12P7/62 ,  C07B2200/07 ,  C07C67/343 ,  C07C253/30 ,  C07D319/06 ,  C07C69/716 ,  C07C255/21 ,  C07C69/738

    摘要： This invention provides a process for producing a 5-hydroxy-3-oxopentanoic acid, a useful pharmaceutical intermediate, easily from a readily available, inexpensive starting material without using any extraordinary production equipment such as a very-low-temperature reactor. Thus, this invention provides a process for producing a 5-hydroxy-3-oxopentanoic acid which comprises permitting a lithium amide to act upon a mixture of an acetic acid ester and a 3-hydroxypropionic acid derivative at not below −20° C. Further, this invention also provides a process for producing a 5-hydroxy-3-oxopentanoic acid which comprises treating a mixture of an acetic acid ester and a 3-hydroxypropionic acid derivative with a Grignard reagent to prepare a mixture of a compound and an acetic acid ester of the above formula (I), and permitting a lithium amide to act upon the mixture at a temperature not below −20° C.

    摘要翻译： 本发明提供一种生产5-羟基-3-氧代戊酸的方法，该方法是一种有用的药物中间体，容易从现成的廉价起始原料中生产，而不使用任何非常低的生产设备如极低温反应器。因此， 本发明提供了一种生产5-羟基-3-氧代戊酸的方法，其包括允许氨化锂在不低于-20℃下作用于乙酸酯和3-羟基丙酸衍生物的混合物。此外，本发明还 提供了一种生产5-羟基-3-氧代戊酸的方法，其包括用格氏试剂处理乙酸酯和3-羟基丙酸衍生物的混合物，以制备上式的化合物和乙酸酯的混合物 （I）化合物，并允许在不低于-20℃的温度下使氨基化锂作用于混合物。

    PROCESS BELT FOR PAPERMAKING AND METHOD FOR MAKING THE SAME
    17.
    发明申请
    PROCESS BELT FOR PAPERMAKING AND METHOD FOR MAKING THE SAME 有权
    造纸用工艺皮带及其制造方法

    公开(公告)号：US20110127000A1

    公开(公告)日：2011-06-02

    申请号：US12954792

    申请日：2010-11-26

    申请人： Takao Yazaki ,  Atsushi Ishino ,  Kenji Inoue ,  Ai Tamura

    发明人： Takao Yazaki ,  Atsushi Ishino ,  Kenji Inoue ,  Ai Tamura

    IPC分类号： D21G9/00 ,  B05D3/02

    CPC分类号： D21F3/0227 ,  Y10S162/901

    摘要： A process belt for papermaking with a long operational life comprises an integrated structure of a reinforcing fibrous base material 6 and a polyurethane layer, the reinforcing fibrous base material being embedded in the polyurethane, wherein an inorganic filler selected from calcined kaolin clay, fused silica and zeolite is homogeneously dispersed in the polyurethane.

    摘要翻译： 用于造纸的工艺带具有长的使用寿命，包括加强纤维基材6和聚氨酯层的整体结构，该增强纤维基材嵌入聚氨酯中，其中选自煅烧高岭土，熔融二氧化硅和 沸石均匀分散在聚氨酯中。

    Wet paper web transfer belt
    19.
    发明授权
    Wet paper web transfer belt 有权
    湿纸幅转印带

    公开(公告)号：US07285185B2

    公开(公告)日：2007-10-23

    申请号：US10966891

    申请日：2004-10-15

    申请人： Kenji Inoue ,  Hiroyuki Takamura

    发明人： Kenji Inoue ,  Hiroyuki Takamura

    IPC分类号： D21F2/00 ,  B32B5/28 ,  B32B5/30 ,  B32B27/04

    CPC分类号： D21F7/086 ,  D21F7/083 ,  Y10S162/901 ,  Y10T428/24372 ,  Y10T442/2131 ,  Y10T442/2164 ,  Y10T442/2484 ,  Y10T442/3374

    摘要： A wet paper web transfer belt comprises a base body, a wet paper web side layer, and a machine side layer. The wet paper web side layer is formed of a high molecular weight elastic section, and fibers and filler particles are exposed at its surface. The fibers and filler particles are exposed in the form of an island-sea structure comprising islands section where the fibers are exposed, and a sea section where the filler particles are exposed. The fibers and the filler particles, both exposed at the wet paper web side layer, hold water at different times in the papermaking process as the wet paper web moves out of the press part of the papermaking machine.

    摘要翻译： 湿纸幅转印带包括基体，湿纸幅侧层和机器侧层。 湿纸幅侧层由高分子量弹性部分形成，纤维和填料颗粒在其表面露出。 纤维和填料颗粒以海绵结构的形式暴露，其中包括岛部分，其中纤维被暴露，以及填充颗粒暴露的海洋部分。 在湿纸幅侧层露出的纤维和填料颗粒在造纸过程中随着湿纸幅移出造纸机的压榨部分而在不同时间保持水分。

    Image forming apparatus
    20.
    发明申请
    Image forming apparatus 审中-公开
    图像形成装置

    公开(公告)号：US20070092289A1

    公开(公告)日：2007-04-26

    申请号：US11476790

    申请日：2006-06-29

    申请人： Yuki Nagamori ,  Kenji Inoue ,  Yusuke Kitagawa ,  Masato Serizawa

    发明人： Yuki Nagamori ,  Kenji Inoue ,  Yusuke Kitagawa ,  Masato Serizawa

    IPC分类号： G03G15/02

    CPC分类号： G03G15/0225 ,  G03G15/0233

    摘要： An image forming apparatus includes a charge roll which charges a body to be charged by contact charge, and a roll-like sponge member which is supported such that it comes into contact with a surface of the charge roll and which is rotated together with the charge roll. The roll-like sponge member and the charge roll have physical characteristics such that a surface of the charge roll is scraped away by contact with the roll-like sponge member.

    摘要翻译： 图像形成装置包括：充电辊，其通过接触电荷对被充电的体进行充电;以及辊状海绵构件，其被支撑成使其与充电辊的表面接触并与电荷一起旋转 滚。 辊状海绵构件和充电辊具有物理特性，使得充电辊的表面通过与辊状海绵构件接触而刮掉。