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11.发明授权公开(公告)号：US07601810B2
公开(公告)日：2009-10-13
申请号：US11677632
申请日：2007-02-22
申请人： Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janet A. Rice , Clement W. K. Waine
发明人： Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janet A. Rice , Clement W. K. Waine
CPC分类号： C07K14/415 , C12N15/8286 , Y02A40/162
摘要： The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
摘要翻译： 本发明涉及编码植物环肽的分离的核酸。 本发明还涉及在正义或反义方向上构建编码全部或部分植物环肽的嵌合基因，其中嵌合基因的表达导致在转化的宿主细胞中产生改变水平的植物环磷酰胺。
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12.发明授权公开(公告)号：US07211658B2
公开(公告)日：2007-05-01
申请号：US11236922
申请日：2005-09-28
申请人： Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janet A. Rice , Clement W. K. Waine
发明人： Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janet A. Rice , Clement W. K. Waine
CPC分类号： C07K14/415 , C12N15/8286 , Y02A40/162
摘要： The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
摘要翻译： 本发明涉及编码植物环肽的分离的核酸。 本发明还涉及在正义或反义方向上构建编码全部或部分植物环肽的嵌合基因，其中嵌合基因的表达导致在转化的宿主细胞中产生改变水平的植物环磷酰胺。
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公开(公告)号：US07202214B2
公开(公告)日：2007-04-10
申请号：US11092429
申请日：2005-03-29
申请人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
发明人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
IPC分类号： A61K38/17 , C07K14/435
CPC分类号： C12N15/8282 , C07K14/43563 , Y10S530/858
摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include polypeptides that possess antimicrobial properties, particularly fungicidal properties, and the encoding nucleic acid molecules. The polypeptides of the invention are isolated from the hemolymph and fat bodies of insect larvae induced by injection of plant pathogenic fungi. Further provided are plant cells, plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.
摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括具有抗微生物特性，特别是杀真菌性质和编码核酸分子的多肽。 通过注射植物致病真菌诱导的昆虫幼虫的血淋巴和脂肪体分离本发明的多肽。 进一步提供了用本发明的核酸分子转化的植物细胞，植物和种子，以赋予植物抗病性。
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14.发明授权Nucleic acid encoding the FUS6 antimicrobial polypeptide of Agrotis ipsilon and its use to enhance disease resistance in a plant 失效编码Agrotis ipsilon的FUS6抗微生物多肽的核酸及其在植物中增强抗病性的用途公开(公告)号：US06891085B2
公开(公告)日：2005-05-10
申请号：US10125258
申请日：2002-04-18
申请人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
发明人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
IPC分类号： C07K14/435 , C12N1/15 , C12N1/19 , C12N1/21 , C12N7/01 , C12N15/12 , C12N15/82 , A10H5/00 , C12N15/11 , C12N15/63 , A10H5/10
CPC分类号： C12N15/8282 , C07K14/43563 , Y10S530/858
摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include nucleic acid molecules encoding Fus6 polypeptides derived from Agrotis ipsilon that possess antimicrobial properties, particularly fungicidal properties. Further provided are plant cells plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.
摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括编码具有抗微生物性质，特别是杀真菌性质的源自Agrotis ipsilon的Fus6多肽的核酸分子。 还提供了用本发明的核酸分子转化的植物细胞植物及其种子，以赋予植物抗病性。
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15.发明授权公开(公告)号：US07589177B2
公开(公告)日：2009-09-15
申请号：US11736633
申请日：2007-04-18
IPC分类号： A61K35/78
CPC分类号： C12N15/8285 , C07K14/415 , C12N15/8282 , Y02A40/164
摘要： The present invention relates to isolated nucleic acids encoding plant cyclotides. The invention also relates to the construction of a chimeric gene encoding all or a portion of the plant cyclotides, in sense or antisense orientation, wherein expression of the chimeric gene results in the production of altered levels of plant cyclotides in a transformed host cell.
摘要翻译： 本发明涉及编码植物环肽的分离的核酸。 本发明还涉及在正义或反义方向上构建编码全部或部分植物环肽的嵌合基因，其中嵌合基因的表达导致在转化的宿主细胞中产生改变水平的植物环磷酰胺。
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16.发明授权Isolated nucleic acid molecules encoding orally active androctonus amoreuxi pesticidal biopeptides 有权分离编码口服活性的芦荟杀虫生物肽的核酸分子公开(公告)号：US07414173B1
公开(公告)日：2008-08-19
申请号：US10617978
申请日：2003-07-11
IPC分类号： A01H5/00 , A01H5/10 , C12N15/82 , C12N15/12 , C07K14/435
CPC分类号： C12N15/8286 , C07K14/43522 , Y02A40/162
摘要： The present invention provides compositions and methods for isolated nucleic acid molecules encoding orally active Androctonus amoreuxi pesticidal polypeptides. Compositions include novel nucleotide sequences encoding Androctonus amoreuxi pesticidal polypeptides, and biologically active variants thereof. Further provided are methods for modulating the pesticide resistance of plants using the nucleotide sequences disclosed herein. One method comprises stably transforming into the genome of a plant cell a nucleotide sequence of the present invention operably linked to a heterologous promoter and regenerating a stably transformed plant that expresses the nucleotide sequence. An additional method comprises incorporating a nucleotide sequence of the present invention operably linked to a heterologous promoter into a microorganism and applying said microorganism to the environment of a plant.
摘要翻译： 本发明提供了编码口服活性黄芪杀虫多肽的分离的核酸分子的组合物和方法。 组合物包括编码Androctonus amoreuxi杀虫多肽的新型核苷酸序列及其生物活性变体。 还提供了使用本文公开的核苷酸序列调节植物的农药抗性的方法。 一种方法包括稳定地转化到植物细胞的基因组中，本发明的核苷酸序列与异源启动子可操作地连接并再生表达核苷酸序列的稳定转化的植物。 另外的方法包括将可操作地连接到异源启动子的本发明的核苷酸序列并入微生物并将所述微生物施用于植物的环境。
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17.发明授权FUS6 nucleic acid molecules and methods of their use in enhancing disease resistance in plants 失效FUS6核酸分子及其用于增强植物抗病性的方法公开(公告)号：US07262342B2
公开(公告)日：2007-08-28
申请号：US11092027
申请日：2005-03-29
申请人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
发明人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
CPC分类号： C12N15/8282 , C07K14/43563 , Y10S530/858
摘要： The present invention is directed to nucleic acid molecules that encode Fus6 defensive polypeptides and methods of their use in enhancing disease resistance of a plant to a fungal pathogen. Vectors, expression cassettes, viruses, cells, and plants comprising a nucleotide sequence of the invention are further provided.
摘要翻译： 本发明涉及编码Fus6防御多肽的核酸分子及其用于增强植物对真菌病原体的抗病性的方法。 进一步提供载体，表达盒，病毒，细胞和包含本发明的核苷酸序列的植物。
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公开(公告)号：US07064184B2
公开(公告)日：2006-06-20
申请号：US11093225
申请日：2005-03-29
申请人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F.H. Wong
发明人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F.H. Wong
CPC分类号： C12N15/8282 , C07K14/43563 , Y10S530/858
摘要： The methods and compositions of the present invention find use in impacting microbial pathogens and in enhancing disease resistance to pathogens, particularly by plants. The compositions of the invention include polypeptides that possess antimicrobial properties, particularly fungicidal properties, and the encoding nucleic acid molecules. The polypeptides of the invention are isolated from the hemolymph and fat bodies of insect larvae induced by injection of plant pathogenic fungi. Further provided are plant cells, plants, and seed thereof, transformed with the nucleic acid molecules of the invention so as to confer disease resistance on the plant.
摘要翻译： 本发明的方法和组合物用于影响微生物病原体并增强对病原体的抗病性，特别是植物的抗病性。 本发明的组合物包括具有抗微生物特性，特别是杀真菌性质和编码核酸分子的多肽。 通过注射植物致病真菌诱导的昆虫幼虫的血淋巴和脂肪体分离本发明的多肽。 进一步提供了用本发明的核酸分子转化的植物细胞，植物和种子，以赋予植物抗病性。
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公开(公告)号：US20090011999A1
公开(公告)日：2009-01-08
申请号：US12171822
申请日：2008-07-11
CPC分类号： C12N15/8286 , C07K14/43522 , Y02A40/162
摘要： The present invention provides compositions and methods for orally active Androctonus amoreuxi pesticidal polypeptides. Compositions include novel Androctonus amoreuxi pesticidal polypeptides and biologically active variants thereof. Further provided are methods for modulating the pesticide resistance of plants by expressing the sequences disclosed herein. One method comprises stably transforming into the genome of a plant cell a nucleotide sequence of the present invention operably linked to a heterologous promoter and regenerating a stably transformed plant that expresses the nucleotide sequence. An additional method comprises incorporating a nucleotide sequence of the present invention operably linked to a heterologous promoter into a microorganism and applying said microorganism to the environment of a plant.
摘要翻译： 本发明提供了口服活性黄芪杀虫多肽的组合物和方法。 组合物包括新颖的安德龙（Amroctonus amoreuxi）杀虫多肽及其生物活性变体。 还提供了通过表达本文公开的序列调节植物的农药抗性的方法。 一种方法包括稳定地转化到植物细胞的基因组中，本发明的核苷酸序列与异源启动子可操作地连接并再生表达核苷酸序列的稳定转化的植物。 另外的方法包括将可操作地连接到异源启动子的本发明的核苷酸序列并入微生物并将所述微生物施用于植物的环境。
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公开(公告)号：US07323623B2
公开(公告)日：2008-01-29
申请号：US11093088
申请日：2005-03-29
申请人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
发明人： Daniel J. Altier , Rafael Herrmann , Albert L. Lu , Billy F. McCutchen , James K. Presnail , Janine L. Weaver , James F. H. Wong
CPC分类号： C12N15/8282 , C07K14/43563 , Y10S530/858
摘要： The present invention is directed to nucleic acid molecules tat encode defensive polypeptides and methods of their use in enhancing disease resistance of a plant to a fungal pathogen. Vectors, expression cassettes, viruses, cells, and plants comprising a nucleotide sequence of the invention are farther provided.
摘要翻译： 本发明涉及编码防御性多肽的核酸分子及其用于增强植物对真菌病原体的抗病性的方法。 提供了包含本发明的核苷酸序列的载体，表达盒，病毒，细胞和植物。
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