公开(公告)号：US10772512B2

公开(公告)日：2020-09-15

申请号：US15680931

申请日：2017-08-18

Applicant: Apple Inc.

Inventor： Erno H. Klaassen ,  Wren Nancy Dougherty ,  Richard C. Kimoto ,  Ravi Narasimhan ,  Thomas J. Sullivan ,  Stephen J. Waydo ,  Todd K. Whitehurst ,  Santiago Quijano ,  Derek Park-Shing Young ,  Zijing Zeng

IPC: A61B5/021 ,  A61B5/00 ,  A61B5/11 ,  A61B5/1455 ,  G06F19/00

Abstract: The present invention provides non-invasive devices, methods, and systems for determining a pressure of blood within a cardiovascular system of a user, the cardiovascular system including a heart and the user having a wrist covered by skin. More particularly, the present invention discloses a variety of wrist-worn devices having a variety of sensors configured to non-invasively engage the skin on the wrist of the user for sensing a variety of user signals from the cardiovascular system of the user. Generally, approaches disclosed herein may passively track blood pressure values without any interaction required on the part of the user or may allow for on demand or point measurements of blood pressure values by having a user actively interact with the sensors of the wrist-worn device. Approaches disclosed herein further allow for absolute blood pressure values to be determined directly without the requirement for any periodic calibrations or for relative blood pressure values to be tracked so as to provide relative blood pressure indices.

公开(公告)号：US11478193B2

公开(公告)日：2022-10-25

申请号：US16565090

申请日：2019-09-09

Applicant: Apple Inc.

Inventor： Chad A. Bossetti ,  Thomas J. Sullivan ,  Xiaoyu Guo ,  Paras Samsukha ,  Anirban Chatterjee

IPC: A61B5/00 ,  A61B5/30 ,  A61B5/304 ,  A61B5/24

Abstract: Detecting user contact with one or more electrodes of a physiological signal sensor can be used to ensure physiological signals measured by the physiological signal sensor meet waveform characteristics (e.g., of a clinically accurate physiological signal). In some examples, a mobile and/or wearable device can comprise sensing circuitry, stimulation circuitry, and processing circuitry. The stimulation circuit can drive one or more stimulation signals on one or more electrodes, the resulting signal(s) can be measured (e.g., by the sensing circuitry), and the processing circuitry can determine whether a user is in contact with the electrode(s). Additionally or alternatively, in some examples, mobile and/or wearable device can comprise saturation detection circuitry, and the processing circuitry can determine whether the sensing circuitry is saturated.

公开(公告)号：US20200367760A1

公开(公告)日：2020-11-26

申请号：US16987851

申请日：2020-08-07

Applicant: Apple Inc.

Inventor： Erno H. Klaassen ,  Wren Nancy Dougherty ,  Richard C. Kimoto ,  Ravi K. Narasimhan ,  Thomas J. Sullivan ,  Stephen J. Waydo ,  Todd K. Whitehurst ,  Santiago Quijano ,  Derek Park-Shing Young ,  Zijing Zeng

IPC: A61B5/021 ,  A61B5/00 ,  A61B5/11

Abstract: Methods and devices for obtaining a blood pressure measurement of a subject measure a transit time of a blood pulse of the subject. A method includes sensing, with a pulse ejection sensor of a wrist-worn device, ejection of blood from the left ventricle. Arrival of a resulting blood pressure pulse at the wrist is sensed via a pulse arrival sensor of the wrist-worn device. A transit time of the blood pressure pulse from the left ventricle to the wrist is determined. A relative blood pressure value of the subject is determined based on the transit time. A reference absolute blood pressure value associated with the relative blood pressure value is received. An absolute blood pressure value for the relative blood pressure value is determined based on the reference absolute blood pressure value and the relative blood pressure value.

公开(公告)号：US10779738B2

公开(公告)日：2020-09-22

申请号：US15681024

申请日：2017-08-18

Applicant: Apple Inc.

Inventor： Thomas J. Sullivan ,  Wren Nancy Dougherty ,  Richard C. Kimoto ,  Erno Klaassen ,  Ravi Narasimhan ,  Stephen J. Waydo ,  Todd K. Whitehurst ,  Derek Park-Shing Young ,  Santiago Quijano ,  Zijing Zeng

IPC: A61B5/021 ,  A61B5/0408 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/024 ,  A61B5/053

Abstract: Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device include a wrist-worn elongate band, at least four EKG or ICG electrodes coupled to the wrist-worn device for detecting a ventricular ejection of a heart, a photo-plethysmogram (PPG) sensor coupled to the wrist-worn device for detecting arrival of a blood pressure pulse at the user's wrist, and a controller configured to calculate a pulse transit time (PTT) for the blood pressure pulse. The controller calculates one or more blood pressure values for the user based on the PTT.

公开(公告)号：US10517489B2

公开(公告)日：2019-12-31

申请号：US15507607

申请日：2015-09-08

Applicant: Apple Inc.

Inventor： Ravi Narasimhan ,  Richard C. Kimoto ,  Thomas J. Sullivan ,  Todd K. Whitehurst ,  Derek Park-shing Young ,  Zijing Zeng ,  Erno Klaassen

IPC: A61B5/021 ,  A61B5/11 ,  A61B5/00 ,  A61B5/024

Abstract: Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device includes an accelerometer, a photo-lethysmogram (PPG) or a pulse pressure sensor, and a controller. The PPG or the pulse pressure sensor coupled to the wrist-worn device for detecting an arrival of a blood pressure pulse at the user's wrist. The controller is configured to process output signals from the accelerometer to detect when the blood pressure pulse is propagated from the left ventricle of the user's heart, process a signal from the PPG or the pulse pressure sensor to detect when the blood pressure pulse arrives at the wrist, calculate a pulse transit time (PTT) for propagation of the blood pressure pulse from the left ventricle to the wrist, and generate one or more blood pressure values for the user based on the PTT.

公开(公告)号：US20170340209A1

公开(公告)日：2017-11-30

申请号：US15680931

申请日：2017-08-18

Applicant: Apple, Inc.

Inventor： Erno H. Klaassen ,  Wren Nancy Dougherty ,  Richard C. Kimoto ,  Ravi Narasimhan ,  Thomas J. Sullivan ,  Stephen J. Waydo ,  Todd K. Whitehurst ,  Santiago Quijano ,  Derek Park-Shing Young ,  Zijing Zeng

IPC: A61B5/021 ,  A61B5/00 ,  G06F19/00

Abstract: The present invention provides non-invasive devices, methods, and systems for determining a pressure of blood within a cardiovascular system of a user, the cardiovascular system including a heart and the user having a wrist covered by skin. More particularly, the present invention discloses a variety of wrist-worn devices having a variety of sensors configured to non-invasively engage the skin on the wrist of the user for sensing a variety of user signals from the cardiovascular system of the user. Generally, approaches disclosed herein may passively track blood pressure values without any interaction required on the part of the user or may allow for on demand or point measurements of blood pressure values by having a user actively interact with the sensors of the wrist-worn device. Approaches disclosed herein further allow for absolute blood pressure values to be determined directly without the requirement for any periodic calibrations or for relative blood pressure values to be tracked so as to provide relative blood pressure indices.