公开(公告)号：US3657445A

公开(公告)日：1972-04-18

申请号：US3657445D

申请日：1970-05-11

Applicant: BAYER AG

Inventor： BUCHEL KARL H ,  REGEL ERIK ,  PLEMPEL MANFRED

IPC: C07D233/62 ,  C07D235/06 ,  C07D235/08 ,  C07D235/18 ,  C07D521/00 ,  A61K27/00

CPC classification number: C07D249/08 ,  C07D231/12 ,  C07D233/56 ,  C07D235/06 ,  C07D235/08 ,  C07D235/18

Abstract: N-TRITYL-IMIDAZOLES AND SALTS THEREOF OF THE FORMULA:

1-(((X)N-PHENYL)-C(-(PHENYLENE)-(X")N")(-(PHENYLENE)-

(X'')N'')-),2-R,4-R'',5-R2-IMIDAZOLE

WHEREIN R, R1 AND R2 ARE HYDROGEN, LOWER ALKLY OR PHENYL, OR R1 AND R2 TOGETHER FORM AN ANELLATED BENZENE RING, X, X'' AND X" ARE ALKYL OF 1 TO 12 CARBON ATOMS OR AN ELECTRO-NEGATIVE MOIETY, AND N, N'' AND N" ARE AN INTEGER FROM 0 TO 2, OR PHARMACEUTICALLY ACCEPTABLE ACID SALTS THEREOF MAY BE PRODUCED BY REACTING A SILVER SALT OR ALKALI METAL SALT OF AN IMIDAZOLE OF THE FORMULA:

2-R,4-R1,5-R2-IMIDAZOLE

WITH A TRITYL HALIDE OF THE FORMULA:

(X)N,(((X'')N''-PHENYL)-C(-HAL)(-(PHENYLENE)-(X")N")-)-

BENZENE

WHEREIN THE SUBSTITUENTS ARE AS ABOVE DEFINED AND HAL IS HALOGEN. THESE COMPOUNDS ARE USEFUL AS ANTIMYCOTICS.

公开(公告)号：US3705930A

公开(公告)日：1972-12-12

申请号：US3705930D

申请日：1970-04-22

Applicant: BAYER AG

Inventor： SCHLOR HANSHELMUT ,  HOFFMANN HELLMUT ,  REGEL ERIK ,  SCHEINPFLUG HANS

IPC: C07F9/18 ,  A01N9/36 ,  C07F9/16

CPC classification number: C07F9/18

Abstract: S-MONOALKYL-S,S-DIPHENYL- OR S,S-DIALKYL-S-PHENYL-TRITHIOLPHOSPHORIC ACID ESTERS IN WHICH EACH ALKYL GROUP HAS FROM 1 TO 4 CARBON ATOMS, E.G., S-METHYL (OR -THYL, -PROYL, -BUTYL)-S,S-DIPHENYLTRITHIOLPHOSPHORIC ACID ESTER, S,S,-DIMETHYL (OR -DIETHYL, -DI-PROPYL, DI-BTYL-)PHENYLTRITHIOLPHOSPHORIC ACID ESTER, HAVE EXCEPTIONAL FUNGICIDAL ACTIVITY, ESPECIALLY AGAINST RICE PATHOGENS, AND FURTHER EXHIBIT INSECTICIDAL AND ACARICIDAL EFFECTIVENESS.

公开(公告)号：US3691192A

公开(公告)日：1972-09-12

申请号：US3691192D

申请日：1970-05-15

Applicant: BAYER AG

Inventor： BUCHEL KARL-HEINZ ,  REGEL ERIK ,  GREWE FERDINAND ,  SCHEINPFLUG HANS ,  KASPERS HELMUT

IPC: C07D233/56 ,  A01N43/50 ,  A01P3/00 ,  C07D233/62 ,  C07D521/00 ,  C07D49/36

CPC classification number: C07D231/12 ,  A01N43/50 ,  C07D233/56 ,  C07D249/08

Abstract: N-trityl-imidazoles of the formula:

IN WHICH R is selected from the group consisting of halo, nitro, cyano, alkyl of one to three carbon atoms, alkoxy of one to three carbon atoms alkylmercapto of one to three carbon atoms and fluoro-substituted alkyl of one to two carbon atoms, are effective against fungi pathogenic to plants.

公开(公告)号：US3665078A

公开(公告)日：1972-05-23

申请号：US3665078D

申请日：1970-09-02

Applicant: BAYER AG

Inventor： BUCHEL KARL-HEINZ ,  REGEL ERIK ,  GREWE FERDINAND ,  SCHEINPFLUG HANS ,  KASPERS HELMUT

IPC: C07D233/56 ,  A01N43/50 ,  A01P3/00 ,  C07D233/62 ,  C07D521/00 ,  A01N9/22

CPC classification number: C07D231/12 ,  A01N43/50 ,  C07D233/56 ,  C07D249/08

Abstract: Plant fungicidal compositions are produced which comprise an amount of a compound of the formula:

WHEREIN R is nitro, sufficient to be effective for killing, combatting or controlling plant fungi, in combination with a solid or liquid diluent or carrier. Methods for killing, combatting or controlling fungal diseases in plants comprise applying to the fungi or to the plant to be protected an effective or toxic amount of the above compound.

公开(公告)号：US3657442A

公开(公告)日：1972-04-18

申请号：US3657442D

申请日：1970-05-11

Applicant: BAYER AG

Inventor： BUCHEL KARL H ,  REGEL ERIK ,  PLEMPEL MANFRED

IPC: C07D233/62 ,  C07D235/06 ,  C07D235/08 ,  C07D235/18 ,  C07D521/00 ,  A61K27/00

CPC classification number: C07D249/08 ,  C07D231/12 ,  C07D233/56 ,  C07D235/06 ,  C07D235/08 ,  C07D235/18

Abstract: N-TRITYL-IMIDAZOLES AND SALTS THEREOF OF THE FORMULA:
WHEREIN R, R1 AND R2 ARE HYDROGEN, LOWER ALKYL OR PHENYL, OR R1 AND R2 TOGETHER FORM AN ANNULATED BENZENE RING, X,X'' AND X" ARE ALKYL OF 1 TO 12 CARBON ATOMS OR AN ELECTRO-NEGATIVE MOIETY, AND N, N'' ARE AN INTEGER FROM 0 TO 2, OR PHARMACEUTICALLY ACCEPTABLE A ACID SALTS THEREOF MAY BE PRODUCED BY REACTING A SILVER SALT OR ALKALI METAL SALT OF AN IMIDAZOLE OF THE FORMULA:

2-R,4-R'',5-R2-IMIDAZOLE

WITH A TRITYL HALIDE OF THE FORMULA:

(X)N,(((X'')N-PHENYL)-C(-HAL)(-(PHENYLENE)-(X")N")-)BENZENE

WHEREIN THE SUBSTITUENTS ARE AS ABOVE DEFINED AND HAL IS HALOGEN. THESE COMPOUNDS ARE USEFUL AS ANTIMYCOTICS.

1-(((X)N-PHENYL)-C(-(PHENYLENE)-(X")N")(-(PHENYLENE)-

(X'')N'')-),2-R,4-R1,5-R2-IMIDAZOLE