公开(公告)号：US20170247385A1

公开(公告)日：2017-08-31

申请号：US15500110

申请日：2015-08-04

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Tao Wang ,  Kyle J. Eastman ,  Zhongxing Zhang ,  Kyle E. Parcella ,  John F. Kadow

IPC: C07D491/048 ,  C07B59/00

CPC classification number: C07D491/048 ,  C07B59/002 ,  C07B2200/05

Abstract: Compounds of formula I, including their salts, as well as compositions and methods of using the compounds are set forth. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

公开(公告)号：US09738653B2

公开(公告)日：2017-08-22

申请号：US14773123

申请日：2014-03-12

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Kap-Sun Yeung ,  Kyle J. Eastman ,  Kyle E. Parcella

IPC: C07D491/048 ,  C07D491/04 ,  C07D307/84

CPC classification number: C07D491/048 ,  C07D307/84 ,  C07D491/04

Abstract: The disclosure provides compounds of formula I or II, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

公开(公告)号：US20130197012A1

公开(公告)日：2013-08-01

申请号：US13798286

申请日：2013-03-13

Applicant: Bristol-Myers Squibb Company

Inventor： Kap-Sun Yeung ,  Kyle E. Parcella ,  John A. Bender ,  Brett R. Beno ,  Katharine A. Grant-Young ,  Ying Han ,  Piyasena Hewawasam ,  John F. Kadow ,  Andrew Nickel

IPC: A61K31/506 ,  A61K45/06

CPC classification number: A61K31/506 ,  A61K45/06 ,  C07D307/84 ,  C07D405/04 ,  C07D405/10 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  C07D413/10 ,  C07D413/12 ,  C07D417/10 ,  C07D417/12 ,  C07D453/00 ,  C07D491/10

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract translation: 本公开提供式I化合物，包括其盐，以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。