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Patent Agency Ranking
公开(公告)号：US08889712B2
公开(公告)日：2014-11-18
申请号：US13921467
申请日：2013-06-19
Applicant: Bristol-Myers Squibb Company
Inventor： Robert M. Borzilleri , Heidi L. Perez , Erik M. Stang , Kyoung S. Kim
IPC: A61K31/47 , C07D401/12 , C07D401/14 , C07K7/02 , A61K38/08 , C07D413/14 , A61K45/06 , C07D401/04
CPC classification number: A61K38/08 , A61K45/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D413/14 , C07K7/02
Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Abstract translation: 公开了利用本发明化合物调节凋亡抑制剂（IAP）的活性的化合物，含有所述化合物的药物组合物和治疗增殖性疾病和失调性细胞凋亡障碍的疾病的方法。
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公开(公告)号：US09783573B2
公开(公告)日：2017-10-10
申请号：US14428688
申请日：2013-09-17
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Robert M. Borzilleri , Kyoung S. Kim , Heidi L. Perez , Erik M. Stang , David K. Williams , Liping Zhang
IPC: C07K5/08 , C07K5/083 , A61K38/06 , A61K45/06 , C07D401/14 , C07D413/14 , C07D401/06 , C07D401/10 , C07D401/12 , C07D417/14 , C07D487/04
CPC classification number: C07K5/0806 , A61K38/06 , A61K45/06 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
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公开(公告)号：US09603889B2
公开(公告)日：2017-03-28
申请号：US14432517
申请日：2013-10-01
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Kyoung S. Kim , Liping Zhang , Donna D. Wei
CPC classification number: A61K38/08 , A61K38/00 , A61K45/06 , C07K5/0806 , C07K7/06
Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
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公开(公告)号：US20150322111A1
公开(公告)日：2015-11-12
申请号：US14428688
申请日：2013-09-17
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Robert M. Borzilleri , Kyoung S. Kim , Heidi L. Perez , Erik M. Stang , David K. Williams , Liping Zhang
CPC classification number: C07K5/0806 , A61K38/06 , A61K45/06 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Abstract translation: 公开了利用本发明化合物调节凋亡抑制剂（IAP）的活性的式（I）化合物，含有所述化合物的药物组合物和治疗增殖性疾病的方法和失调性细胞凋亡障碍（例如癌症）的化合物。
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公开(公告)号：US20150225452A1
公开(公告)日：2015-08-13
申请号：US14419975
申请日：2013-08-06
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Robert M. Borzilleri , Heidi L. Perez , Donna D. Wei , Kyoung S. Kim
CPC classification number: C07K5/0815 , A61K38/06 , A61K45/06 , C07D207/16 , C07D401/12 , C07K5/06026 , C07K5/0806
Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing said compounds.
Abstract translation: 公开了利用所述化合物调节凋亡抑制剂（IAP）的活性的式（I）化合物，含有所述化合物的药物组合物和治疗增殖性疾病的方法和失调性凋亡障碍（例如癌症）的化合物。
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