公开(公告)号：US09845312B2

公开(公告)日：2017-12-19

申请号：US15037402

申请日：2014-11-25

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Norbert Lui

IPC: C07D403/04 ,  C07D231/14 ,  C07D231/16

CPC classification number: C07D403/04 ,  C07D231/14 ,  C07D231/16

Abstract: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein comprising reacting an olefin with an hydrazine.

公开(公告)号：US09512081B2

公开(公告)日：2016-12-06

申请号：US14892291

申请日：2014-05-19

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Norbert Lui ,  Arnd Neeff ,  Winfried Etzel ,  Jean-Pierre Vors ,  Frederic R. Leroux ,  Gregory Landelle ,  Mark James Ford

IPC: C07D231/14 ,  C07D231/12 ,  A01N43/56

CPC classification number: C07D231/12 ,  A01N43/56 ,  C07D231/14

Abstract: The present invention relates to a novel process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from α,α-dihaloamines.

Abstract translation: 本发明涉及从α，α-二卤代胺制备3,5-双（氟代烷基）吡唑衍生物的新方法。

公开(公告)号：US10556867B2

公开(公告)日：2020-02-11

申请号：US16335138

申请日：2017-09-18

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

Inventor： Sergii Pazenok ,  Jean-Pierre Vors ,  Frédéric R. LeRoux ,  Etienne Schmitt

IPC: C07D231/14 ,  C07C251/08 ,  C07C249/02 ,  C07D401/04

Abstract: The present invention relates to a novel process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates from ketimines and oxalic acid derivatives which can be further transformed into 3-fluoroalkyl-5-pyrazolecarboxylic acids.

公开(公告)号：US10189800B2

公开(公告)日：2019-01-29

申请号：US15763181

申请日：2016-09-23

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Christian Funke ,  Arnd Neeff ,  Sergii Pazenok ,  Norbert Lui

IPC: C07D271/113

Abstract: A method for preparing N-(1,3,4-oxadiazol-2-yl)arylcarboxamides of formula (I) is described. The substituents therein are radicals such as hydrogen, alkyl, haloalkyl or aryl.

公开(公告)号：US09765033B2

公开(公告)日：2017-09-19

申请号：US14892280

申请日：2014-05-19

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Norbert Lui

IPC: C07D231/12 ,  C07D231/14 ,  C07C251/80 ,  C07C251/88

CPC classification number: C07D231/12 ,  C07C251/80 ,  C07C251/88 ,  C07D231/14

Abstract: The present invention describes a novel method for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives.

公开(公告)号：US09725415B2

公开(公告)日：2017-08-08

申请号：US15037564

申请日：2014-11-25

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Norbert Lui ,  Christian Funke ,  Arnd Neeff ,  Vadim Mikhailovich Timoshenko ,  Elena Ivanovna Kaminskaya ,  Yuriy Grigorievich Shermolovich

IPC: C07D231/16 ,  C07D403/04 ,  C07D231/14 ,  C07D231/38

CPC classification number: C07D231/16 ,  C07D231/14 ,  C07D231/38 ,  C07D403/04

Abstract: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein, resulting from the reaction of an olefin with hydrazine in the presence of water and a base.

公开(公告)号：US09656966B2

公开(公告)日：2017-05-23

申请号：US15113377

申请日：2015-01-22

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Norbert Lui ,  Sergii Pazenok

IPC: C07D231/16

CPC classification number: C07D231/16

Abstract: The present invention relates to a novel method for preparing 1-alkyl-3-difluoromethyl-5-fluor-1H-pyrazole-4-carbaldehydes or esters thereof of formula (I) by means of reductive dehalogenation, starting from 1-alkyl-3-chlorodifluoromethyl-5-fluoro-1H-pyrazole-4-carbaldehydes or esters thereof Formula (I)

公开(公告)号：US09630898B2

公开(公告)日：2017-04-25

申请号：US15029594

申请日：2014-10-20

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Christian Funke

IPC: C07C45/00 ,  C07C45/67 ,  C07C49/167

CPC classification number: C07C45/676 ,  C07C49/167 ,  C07C49/16

Abstract: The present invention describes a novel method for producing haloketones.

公开(公告)号：US10125103B2

公开(公告)日：2018-11-13

申请号：US15569681

申请日：2016-04-28

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Sergii Pazenok ,  Hans Martin Thomas ,  Frank Volz

IPC: C07D231/16

Abstract: The present invention relates to a novel method for preparing 5-fluoro-1H-pyrazole-4-carbonyl fluorides by halogen exchange reaction of 5-chloro-1H-pyrazole-4-carbonyl chlorides with alkali metal fluorides, using non-polar solvents.

公开(公告)号：US09856222B2

公开(公告)日：2018-01-02

申请号：US15317921

申请日：2015-06-08

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Sergii Pazenok ,  Norbert Lui

IPC: C07D231/12

CPC classification number: C07D231/12 ,  C07D231/14

Abstract: Process for preparing 3,5-bis(haloalkyl)pyrazole derivatives of the formula (I), via acylation of Hydrazones.