公开(公告)号：US10435352B2

公开(公告)日：2019-10-08

申请号：US15769765

申请日：2016-10-21

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Christian Funke ,  Thomas Himmler ,  Sergii Pazenok ,  Christoph Schotes ,  Matthias Beller ,  Thomas Schareina ,  Alexander Zapf

IPC: C07C253/14 ,  C07C255/50 ,  C07C315/02 ,  C07C319/14 ,  C07C319/20 ,  C07C323/62 ,  C07C25/13 ,  C07C323/36

Abstract: A process for preparing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids of the formula (I) is described. Here, the substituents are radicals such as alkyl and substituted phenyl.

公开(公告)号：US10266494B2

公开(公告)日：2019-04-23

申请号：US16070561

申请日：2017-01-13

Applicant: Bayer CropScience Aktiengesellschaft ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Sergii Pazenok ,  Jean-Pierre Vors ,  Frédéric R Leroux ,  Fallia Aribi ,  Etienne Schmitt ,  Armen Panossian

IPC: C07D215/18 ,  C07D215/12 ,  C07D215/26 ,  C07D215/36 ,  C07D215/38

Abstract: The invention relates to a novel process for preparing polyfluoroalkylated quinolines from ketimines in the presence of fluoroalkylamino reagents.

公开(公告)号：US09957256B2

公开(公告)日：2018-05-01

申请号：US15313343

申请日：2015-05-26

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Norbert Lui ,  Christian Funke

IPC: C07D403/04 ,  C07D231/16 ,  C07D231/14 ,  C07C21/18 ,  C07D401/14 ,  C07D231/38

CPC classification number: C07D403/04 ,  C07C21/18 ,  C07D231/14 ,  C07D231/16 ,  C07D231/38 ,  C07D401/14

Abstract: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein and further reactions with this compound.

公开(公告)号：US09656965B2

公开(公告)日：2017-05-23

申请号：US14916496

申请日：2014-09-04

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Peter Bruchner ,  Sergii Pazenok

IPC: C07D231/14 ,  C07D231/16

CPC classification number: C07D231/14 ,  C07D231/16

Abstract: A new one-step process for the preparation of pyrazole carboxamide derivatives of the general formula (I) by reaction of 3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carbaldehyde with an amine or its salt.

公开(公告)号：US09951023B2

公开(公告)日：2018-04-24

申请号：US15022901

申请日：2014-09-04

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Norbert Lui ,  Sergii Pazenok

IPC: C07D231/16 ,  C07D231/14

CPC classification number: C07D231/16 ,  C07D231/14

Abstract: A method for the preparation of compounds of formula (I), for example, N-methyl-3-difluoromethyl-5-fluorpyrazole aldehyde, starting from compounds of formula (II), for example, N-methyl-3-haloalkyl-5 chloropyrazole aldehyde, comprising simultaneous fluorination (one step process) of haloalkyl group in position 3 and replacing haloatom in position 5 by fluorine.

公开(公告)号：US09701640B2

公开(公告)日：2017-07-11

申请号：US15127908

申请日：2015-03-20

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok ,  Norbert Lui ,  Christian Funke ,  Winfried Etzel ,  Arnd Neeff

IPC: C07D231/12 ,  C07C251/08 ,  C07F5/02 ,  C07D231/14

CPC classification number: C07D231/12 ,  C07C251/08 ,  C07D231/14 ,  C07F5/022

Abstract: The present invention relates to a novel process for preparing 3,5-bis(haloalkyl)pyrazole derivatives from α,α-dihaloamines and ketimines.

公开(公告)号：US10906893B2

公开(公告)日：2021-02-02

申请号：US16486516

申请日：2018-02-15

Applicant: Bayer CropScience Aktiengesellschaft ,  Bayer Aktiengesellschaft

Inventor： Sergii Pazenok ,  Christian Funke ,  Friedrich August Muehlthau ,  Mark James Ford ,  Arnd Neeff ,  Klaus-Ulrich Schiffer

IPC: C07D409/12

Abstract: The invention relates to a method for preparing methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylate from 4-methoxycarbonyl-2-methylthiophene-3-sulfonyl chloride in the presence of an imidazole base substituted in the 1-position or in the presence of a mixture of bases comprising an imidazole base substituted in the 1-position (N-alkylimidazole).

公开(公告)号：US10273215B2

公开(公告)日：2019-04-30

申请号：US15738470

申请日：2016-06-21

Applicant: Bayer CropScience Aktiengesellschaft ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Sergii Pazenok ,  Jean-Pierre Vors ,  Frédéric R. Leroux ,  Etienne Schmitt

IPC: C07D231/16 ,  C07C251/08 ,  C07C251/12 ,  C07C251/30 ,  C07C251/26

Abstract: The present invention relates to a novel process for preparing 3,5-bis substituted pyrazoles containing haloalkoxy- and haloalkylthio groups.

公开(公告)号：US10059673B2

公开(公告)日：2018-08-28

申请号：US15504294

申请日：2015-08-14

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Sergii Pazenok

IPC: C07D231/16 ,  C07D231/38 ,  C07D403/04 ,  C07C17/358 ,  C07C17/26

CPC classification number: C07D231/16 ,  C07C17/26 ,  C07C17/358 ,  C07D231/12 ,  C07D231/38 ,  C07D403/04

Abstract: A new process for the preparation of 5-fluoro-1H-pyrazoles of the general formula (I) as described herein and further reactions with this compound.

公开(公告)号：US09914704B2

公开(公告)日：2018-03-13

申请号：US15317927

申请日：2015-06-08

Applicant: Bayer CropScience Aktiengesellschaft

Inventor： Sergii Pazenok ,  Norbert Lui

IPC: C07D231/12 ,  A01N43/56

CPC classification number: C07D231/12 ,  A01N43/56 ,  C07D231/14

Abstract: The present invention relates to a novel process for preparing 3,5-bis(haloalkyl)pyrazole derivatives of the formula (Ia) and (Ib), via acylation of ketimines.