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Patent Agency Ranking
公开(公告)号：US20140134597A1
公开(公告)日：2014-05-15
申请号：US14062351
申请日：2013-10-24
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Alireza Ebrahim , Karl De Vore , Christopher Spates
IPC: C12N5/078
CPC classification number: G01N33/721 , G01N33/5094
Abstract: Intact erythrocytes with selected and often elevated levels of hemoglobin A1c (HbA1c) for use as quality controls for HbA1c assays and assay instruments are prepared by hypotonic dialysis of erythrocytes from a healthy mammal to permeabilize the erythrocyte membranes, infusion of the permeabilized erythrocytes with hemoglobin A1c, and de-permeabilization of the infused erythrocytes. Quality controls of essentially any level of HbA1c can be prepared in this manner and once prepared will be useful for monitoring the entire assay procedure, including the lysis of the erythrocytes in a typical sample.
Abstract translation: 通过对来自健康哺乳动物的红细胞进行低渗透析以透过红细胞膜，用血红蛋白A1c输注透化的红细胞，制备具有选定且经常升高的血红蛋白A1c（HbA1c）水平的完整红细胞，用于HbA1c测定和测定仪器的质量控制 ，以及输注红细胞的不透性化。 可以以这种方式制备基本上任何水平的HbA1c的质量控制，一旦制备将用于监测整个测定程序，包括典型样品中红细胞的裂解。
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公开(公告)号：US09909959B2
公开(公告)日：2018-03-06
申请号：US15296901
申请日：2016-10-18
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Alireza Ebrahim , Christopher Spates , Karl De Vore
CPC classification number: G01N1/28 , C12Q1/32 , G01N21/91 , G01N33/96 , G01N2001/2893 , G01N2333/765 , G01N2496/00 , G01N2496/80
Abstract: Solid beads each containing a selected quantity of analyte are combined and a liquid base matrix that contains attributes of a biological fluid that is to be assayed, together constitute a kit from which a laboratory technician can, at the point of use, prepare a liquid control for a particular analyte, and preferably a series of such controls at different levels of the same analyte customized for a particular assay.
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公开(公告)号：US09506939B2
公开(公告)日：2016-11-29
申请号：US14270701
申请日：2014-05-06
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Alireza Ebrahim , Karl De Vore , Christopher Spates
CPC classification number: G01N33/96 , F26B5/06 , G01N2496/80
Abstract: Provided herein are assay control materials comprising stable analytes and lyophilized unstable analytes, and methods of making and using the same.
Abstract translation: 本文提供了包含稳定分析物和冻干不稳定分析物的测定对照材料及其制备和使用方法。
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公开(公告)号：US20160061694A1
公开(公告)日：2016-03-03
申请号：US14938780
申请日：2015-11-11
Applicant: Bio-Rad Laboratories, Inc. QSD
Inventor： Alireza Ebrahim , Christopher Spates , Karl De Vore
CPC classification number: G01N1/28 , C12Q1/32 , G01N21/91 , G01N33/96 , G01N2001/2893 , G01N2333/765 , G01N2496/00 , G01N2496/80
Abstract: Solid beads each containing a selected quantity of analyte are combined and a liquid base matrix that contains attributes of a biological fluid that is to be assayed, together constitute a kit from which a laboratory technician can, at the point of use, prepare a liquid control for a particular analyte, and preferably a series of such controls at different levels of the same analyte customized for a particular assay.
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公开(公告)号：US20140329263A1
公开(公告)日：2014-11-06
申请号：US14270701
申请日：2014-05-06
Applicant: Bio-Rad Laboratories, Inc.
Inventor： Alireza Ebrahim , Karl De Vore , Christopher Spates
CPC classification number: G01N33/96 , F26B5/06 , G01N2496/80
Abstract: Provided herein are assay control materials comprising stable analytes and lyophilized unstable analytes, and methods of making and using the same.
Abstract translation: 本文提供了包含稳定分析物和冻干不稳定分析物的测定对照材料及其制备和使用方法。
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